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- Roskamp_Institute abstract "The Roskamp Institute, founded by the Robert Roskamp Foundation in Sarasota, Florida in 2003, is a non-profit biomedical research center with an emphasis on Alzheimer's disease. It also operates a memory clinic and clinical research offices in Tampa, Florida. The institute is focused on finding the causes and treatments for neuropsychiatric and neurodegenerative diseases, particularly the Alzheimer's disease. The Institute's lead researchers, Dr. Michael Mullan and Dr. Fiona Crawford were members of a team of scientists who discovered in the early 1990s that the onset of Alzheimer’s disease was directly related to the accumulation of the β-amyloid protein. Drs. Mike Mullan and Fiona Crawford jointly found Swedish mutation in APP gene in the familial form of the disease. Currently Swedish Mutation is widely used in Tg2573 transgenic mouse model of Alzheimer's Disease.In September 2006, the Roskamp Institute tied up with the Institute of Neuroscience of Trinity College, Dublin to launch a clinical trial study to determine if the drug Nilvadipine might be useful in the cure of Alzheimer's disease. The study has been funded by the Roskamp Institute. The aim of the study is to determine if Nilvadipine can alter β-amyloid protein. Nilvadipine is currently used to treat high blood pressure and is available in Ireland on prescription.On May 2011, an international research consortium led by Trinity College Dublin (Ireland) announced the selection for funding of a large-scale European clinical trial of Nilvadipine, an Alzheimer’s disease drug developed at the Roskamp Institute in Sarasota. More than 500 Alzheimer’s patients will participate in the multicenter Phase III clinical trial designed to study the effectiveness of Nilvadipine. Press release regarding this can be found here Roskamp Institute Press ReleaseThe institute is currently housed in a 41,000 sq ft (3,800 m2) scientific research facility (formerly used by Bausch & Lomb) in Sarasota, Florida. The institute facility contains proteomics, genomics, mass spectrometry, pathology, and chemistry labs. Led by Drs. Michael Mullan and Fiona Crawford, the organization employs more than 50 scientists, technicians, and other research staff.Roskamp Institute Scientists are actively involved in Gulf War Syndrome research. They are studying effects of gulf war agents on biological pathways and identifying targets that may help identifying therapy.".
- Roskamp_Institute wikiPageExternalLink www.mullanalzheimer.info.
- Roskamp_Institute wikiPageExternalLink www.rfdn.org.
- Roskamp_Institute wikiPageExternalLink news_release_052511.html.
- Roskamp_Institute wikiPageExternalLink www.roskampgulfwar.org.
- Roskamp_Institute wikiPageExternalLink Neuroscience.
- Roskamp_Institute wikiPageID "9371968".
- Roskamp_Institute wikiPageLength "4444".
- Roskamp_Institute wikiPageOutDegree "21".
- Roskamp_Institute wikiPageRevisionID "679036804".
- Roskamp_Institute wikiPageWikiLink Alzheimers_disease.
- Roskamp_Institute wikiPageWikiLink Amyloid_beta.
- Roskamp_Institute wikiPageWikiLink Bausch_&_Lomb.
- Roskamp_Institute wikiPageWikiLink Category:Biomedical_research_foundations.
- Roskamp_Institute wikiPageWikiLink Chemistry.
- Roskamp_Institute wikiPageWikiLink Clinical_trial.
- Roskamp_Institute wikiPageWikiLink Florida.
- Roskamp_Institute wikiPageWikiLink Genomics.
- Roskamp_Institute wikiPageWikiLink Mass_spectrometry.
- Roskamp_Institute wikiPageWikiLink Medical_research.
- Roskamp_Institute wikiPageWikiLink Memory_clinic.
- Roskamp_Institute wikiPageWikiLink Michael_Mullan.
- Roskamp_Institute wikiPageWikiLink Nilvadipine.
- Roskamp_Institute wikiPageWikiLink Pathology.
- Roskamp_Institute wikiPageWikiLink Proteomics.
- Roskamp_Institute wikiPageWikiLink Robert_Roskamp.
- Roskamp_Institute wikiPageWikiLink Sarasota,_Florida.
- Roskamp_Institute wikiPageWikiLink Swedish_mutation.
- Roskamp_Institute wikiPageWikiLink Tampa,_Florida.
- Roskamp_Institute wikiPageWikiLink Trinity_College,_Dublin.
- Roskamp_Institute wikiPageWikiLinkText "Roskamp Institute".
- Roskamp_Institute wikiPageUsesTemplate Template:Convert.
- Roskamp_Institute wikiPageUsesTemplate Template:Reflist.
- Roskamp_Institute subject Category:Biomedical_research_foundations.
- Roskamp_Institute hypernym Center.
- Roskamp_Institute type Building.
- Roskamp_Institute type Institute.
- Roskamp_Institute type Organization.
- Roskamp_Institute type Organization.
- Roskamp_Institute comment "The Roskamp Institute, founded by the Robert Roskamp Foundation in Sarasota, Florida in 2003, is a non-profit biomedical research center with an emphasis on Alzheimer's disease. It also operates a memory clinic and clinical research offices in Tampa, Florida. The institute is focused on finding the causes and treatments for neuropsychiatric and neurodegenerative diseases, particularly the Alzheimer's disease. The Institute's lead researchers, Dr. Michael Mullan and Dr.".
- Roskamp_Institute label "Roskamp Institute".
- Roskamp_Institute sameAs Q7369000.
- Roskamp_Institute sameAs m.028698x.
- Roskamp_Institute sameAs Q7369000.
- Roskamp_Institute wasDerivedFrom Roskamp_Institute?oldid=679036804.
- Roskamp_Institute isPrimaryTopicOf Roskamp_Institute.