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- Rolofylline abstract "Rolofylline (KW-3902) is an experimental diuretic which acts as a selective adenosine A1 receptor antagonist. It was discovered at NovaCardia, Inc. which was purchased by Merck & Co., Inc. in 2007.Development of rolofylline was terminated on September 1, 2009, after the results of a large clinical trial (PROTECT) showed the drug to be no better than placebo for patients with acute heart failure. Participants given rolofylline did show some improvement in shortness of breath, but the drug did not prevent kidney damage or have any significant effect on overall treatment success. Rolofylline was also associated with a higher incidence of seizures and stroke.".
- Rolofylline atcPrefix "C03".
- Rolofylline atcSuffix "BD".
- Rolofylline casNumber "136199-02-5".
- Rolofylline fdaUniiCode "7805S5HIHX".
- Rolofylline iupacName "8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione".
- Rolofylline pubchem "64627".
- Rolofylline thumbnail Rolofylline.svg?width=300.
- Rolofylline wikiPageID "17253604".
- Rolofylline wikiPageLength "3112".
- Rolofylline wikiPageOutDegree "16".
- Rolofylline wikiPageRevisionID "667232633".
- Rolofylline wikiPageWikiLink Adenosine_A1_receptor.
- Rolofylline wikiPageWikiLink Category:Adenosine_receptor_antagonists.
- Rolofylline wikiPageWikiLink Category:Diuretics.
- Rolofylline wikiPageWikiLink Category:Xanthines.
- Rolofylline wikiPageWikiLink Clinical_trial.
- Rolofylline wikiPageWikiLink Diuretic.
- Rolofylline wikiPageWikiLink Drug_development.
- Rolofylline wikiPageWikiLink Dyspnea.
- Rolofylline wikiPageWikiLink Epileptic_seizure.
- Rolofylline wikiPageWikiLink Incidence_(epidemiology).
- Rolofylline wikiPageWikiLink Merck_&_Co..
- Rolofylline wikiPageWikiLink NovaCardia,_Inc..
- Rolofylline wikiPageWikiLink Placebo.
- Rolofylline wikiPageWikiLink Receptor_antagonist.
- Rolofylline wikiPageWikiLink Statistical_significance.
- Rolofylline wikiPageWikiLink Stroke.
- Rolofylline wikiPageWikiLinkText "Rolofylline".
- Rolofylline atcPrefix "3.0".
- Rolofylline atcSuffix "BD".
- Rolofylline c "20".
- Rolofylline casNumber "136199".
- Rolofylline chemspiderid "58188".
- Rolofylline h "28".
- Rolofylline iupacName "8".
- Rolofylline iupharLigand "5604".
- Rolofylline legalUs "Rx-only".
- Rolofylline molecularWeight "356.46".
- Rolofylline n "4".
- Rolofylline o "2".
- Rolofylline pubchem "64627".
- Rolofylline unii "7805".
- Rolofylline width "220".
- Rolofylline wikiPageUsesTemplate Template:Adenosinergics.
- Rolofylline wikiPageUsesTemplate Template:Cardiovascular-drug-stub.
- Rolofylline wikiPageUsesTemplate Template:Drugbox.
- Rolofylline wikiPageUsesTemplate Template:Fdacite.
- Rolofylline wikiPageUsesTemplate Template:Reflist.
- Rolofylline subject Category:Adenosine_receptor_antagonists.
- Rolofylline subject Category:Diuretics.
- Rolofylline subject Category:Xanthines.
- Rolofylline type Agent.
- Rolofylline type ChemicalSubstance.
- Rolofylline type Drug.
- Rolofylline type Agent.
- Rolofylline type Alkaloid.
- Rolofylline type Antagonist.
- Rolofylline type Diuretic.
- Rolofylline type Drug.
- Rolofylline type ChemicalObject.
- Rolofylline type Thing.
- Rolofylline type Q8386.
- Rolofylline comment "Rolofylline (KW-3902) is an experimental diuretic which acts as a selective adenosine A1 receptor antagonist. It was discovered at NovaCardia, Inc. which was purchased by Merck & Co., Inc. in 2007.Development of rolofylline was terminated on September 1, 2009, after the results of a large clinical trial (PROTECT) showed the drug to be no better than placebo for patients with acute heart failure.".
- Rolofylline label "Rolofylline".
- Rolofylline sameAs Q7361410.
- Rolofylline sameAs ロロフィリン.
- Rolofylline sameAs Rolofilina.
- Rolofylline sameAs m.043shlw.
- Rolofylline sameAs Rolofilin.
- Rolofylline sameAs Rolofilin.
- Rolofylline sameAs Q7361410.
- Rolofylline wasDerivedFrom Rolofylline?oldid=667232633.
- Rolofylline depiction Rolofylline.svg.
- Rolofylline isPrimaryTopicOf Rolofylline.