Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Ro4938581> ?p ?o }
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- Ro4938581 abstract "Ro4938581 is a nootropic drug invented in 2009 by a team working for Hoffmann-La Roche, which acts as a subtype-selective inverse agonist at the α5 subtype of the benzodiazepine binding site on the GABAA receptor. It has good selectivity for the α5 subtype and did not produce convulsant or anxiogenic effects in animal studies, making it a promising potential nootropic. Ro4938581 and a related derivative basmisanil (RG-1662, RO5186582) have subsequently been investigated for the alleviation of cognitive dysfunction in Down syndrome.".
- Ro4938581 iupacName "3-bromo-10-(difluoromethyl)-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]diazepine".
- Ro4938581 pubchem "11624499".
- Ro4938581 thumbnail Ro4938581.svg?width=300.
- Ro4938581 wikiPageID "39673186".
- Ro4938581 wikiPageLength "5515".
- Ro4938581 wikiPageOutDegree "20".
- Ro4938581 wikiPageRevisionID "693481363".
- Ro4938581 wikiPageWikiLink Anxiogenic.
- Ro4938581 wikiPageWikiLink Basmisanil.
- Ro4938581 wikiPageWikiLink Benzodiazepine.
- Ro4938581 wikiPageWikiLink Category:Benzodiazepines.
- Ro4938581 wikiPageWikiLink Category:GABAA_receptor_negative_allosteric_modulators.
- Ro4938581 wikiPageWikiLink Category:Nootropics.
- Ro4938581 wikiPageWikiLink Cognitive_deficit.
- Ro4938581 wikiPageWikiLink Convulsant.
- Ro4938581 wikiPageWikiLink Down_syndrome.
- Ro4938581 wikiPageWikiLink Drug.
- Ro4938581 wikiPageWikiLink GABAA_receptor.
- Ro4938581 wikiPageWikiLink GABRA5.
- Ro4938581 wikiPageWikiLink Hoffmann-La_Roche.
- Ro4938581 wikiPageWikiLink Inverse_agonist.
- Ro4938581 wikiPageWikiLink L-655,708.
- Ro4938581 wikiPageWikiLink Nootropic.
- Ro4938581 wikiPageWikiLink PWZ-029.
- Ro4938581 wikiPageWikiLink Receptor_(biochemistry).
- Ro4938581 wikiPageWikiLink TB-21007.
- Ro4938581 wikiPageWikiLink Α5IA.
- Ro4938581 wikiPageWikiLinkText "Ro4938581".
- Ro4938581 br "1".
- Ro4938581 c "13".
- Ro4938581 f "2".
- Ro4938581 h "8".
- Ro4938581 iupacName "3".
- Ro4938581 iupharLigand "4299".
- Ro4938581 molecularWeight "352.14".
- Ro4938581 n "5".
- Ro4938581 pubchem "11624499".
- Ro4938581 smiles "FCC=CCN4C3=NC=N4".
- Ro4938581 width "222".
- Ro4938581 wikiPageUsesTemplate Template:Benzodiazepines.
- Ro4938581 wikiPageUsesTemplate Template:Cascite.
- Ro4938581 wikiPageUsesTemplate Template:Drugbankcite.
- Ro4938581 wikiPageUsesTemplate Template:Drugbox.
- Ro4938581 wikiPageUsesTemplate Template:GABAergics.
- Ro4938581 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Ro4938581 wikiPageUsesTemplate Template:Nootropics.
- Ro4938581 wikiPageUsesTemplate Template:Reflist.
- Ro4938581 subject Category:Benzodiazepines.
- Ro4938581 subject Category:GABAA_receptor_negative_allosteric_modulators.
- Ro4938581 subject Category:Nootropics.
- Ro4938581 hypernym Drug.
- Ro4938581 type ChemicalSubstance.
- Ro4938581 type Drug.
- Ro4938581 type ChemicalObject.
- Ro4938581 type Thing.
- Ro4938581 type Q8386.
- Ro4938581 comment "Ro4938581 is a nootropic drug invented in 2009 by a team working for Hoffmann-La Roche, which acts as a subtype-selective inverse agonist at the α5 subtype of the benzodiazepine binding site on the GABAA receptor. It has good selectivity for the α5 subtype and did not produce convulsant or anxiogenic effects in animal studies, making it a promising potential nootropic.".
- Ro4938581 label "Ro4938581".
- Ro4938581 sameAs Q15410190.
- Ro4938581 sameAs m.0w1cm9j.
- Ro4938581 sameAs Ro4938581.
- Ro4938581 sameAs Ro4938581.
- Ro4938581 sameAs Q15410190.
- Ro4938581 wasDerivedFrom Ro4938581?oldid=693481363.
- Ro4938581 depiction Ro4938581.svg.
- Ro4938581 isPrimaryTopicOf Ro4938581.