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- Retinal_precursor_cells abstract "Retinal precursor cells are biological cells that differentiate into the various cell types of the retina during development. In the vertebrate, these retinal cells differentiate into seven cell types, including retinal ganglion cells, amacrine cells, bipolar cells, horizontal cells, rod photoreceptors, cone photoreceptors, and Müller glia cells. During embryogenesis, retinal cells originate from the anterior portion of the neural plate termed the eye field. Eye field cells with a retinal fate express several transcription factor markers including Rx1, Pax6, and Lhx2. The eye field gives rise to the optic vesicle and then to the optic cup. The retina is generated from the precursor cells within the inner layer of the optic cup, as opposed to the retinal pigment epithelium that originate from the outer layer of the optic cup. In general, the developing retina is organized so that the least-committed precursor cells are located in the periphery of the retina, while the committed cells are located in the center of the retina. The differentiation of retinal precursor cells into the mature cell types found in the retina is coordinated in time and space by factors within the cell as well as factors in the environment of the cell. One example of an intrinsic regulator of this process is the transcription factor Ath5. Ath5 expression in retinal progenitor cells biases their differentiation into a retinal ganglion cell fate. An example of an environmental factor is the morphogen sonic hedge hog (Shh). Shh has been shown to repress the differentiation of precursor cells into retinal ganglion cells.".
- Retinal_precursor_cells thumbnail Human_eye_cross-sectional_view_grayscale.png?width=300.
- Retinal_precursor_cells wikiPageID "38663170".
- Retinal_precursor_cells wikiPageLength "4821".
- Retinal_precursor_cells wikiPageOutDegree "18".
- Retinal_precursor_cells wikiPageRevisionID "691062047".
- Retinal_precursor_cells wikiPageWikiLink Amacrine_cell.
- Retinal_precursor_cells wikiPageWikiLink Bipolar_neuron.
- Retinal_precursor_cells wikiPageWikiLink Category:Human_cells.
- Retinal_precursor_cells wikiPageWikiLink Category:Human_eye_anatomy.
- Retinal_precursor_cells wikiPageWikiLink Cone_cell.
- Retinal_precursor_cells wikiPageWikiLink Frizzled.
- Retinal_precursor_cells wikiPageWikiLink Muller_glia.
- Retinal_precursor_cells wikiPageWikiLink Optic_cup_(anatomical).
- Retinal_precursor_cells wikiPageWikiLink Optic_vesicle.
- Retinal_precursor_cells wikiPageWikiLink PAX6.
- Retinal_precursor_cells wikiPageWikiLink Retina.
- Retinal_precursor_cells wikiPageWikiLink Retina_horizontal_cell.
- Retinal_precursor_cells wikiPageWikiLink Retinal_ganglion_cell.
- Retinal_precursor_cells wikiPageWikiLink Retinal_pigment_epithelium.
- Retinal_precursor_cells wikiPageWikiLink Rod_cell.
- Retinal_precursor_cells wikiPageWikiLink Sonic_hedgehog.
- Retinal_precursor_cells wikiPageWikiLink Wnt_signaling_pathway.
- Retinal_precursor_cells wikiPageWikiLink File:Human_eye_cross-sectional_view_grayscale.png.
- Retinal_precursor_cells wikiPageUsesTemplate Template:Reflist.
- Retinal_precursor_cells subject Category:Human_cells.
- Retinal_precursor_cells subject Category:Human_eye_anatomy.
- Retinal_precursor_cells hypernym Cells.
- Retinal_precursor_cells type AnatomicalStructure.
- Retinal_precursor_cells type Line.
- Retinal_precursor_cells comment "Retinal precursor cells are biological cells that differentiate into the various cell types of the retina during development. In the vertebrate, these retinal cells differentiate into seven cell types, including retinal ganglion cells, amacrine cells, bipolar cells, horizontal cells, rod photoreceptors, cone photoreceptors, and Müller glia cells. During embryogenesis, retinal cells originate from the anterior portion of the neural plate termed the eye field.".
- Retinal_precursor_cells label "Retinal precursor cells".
- Retinal_precursor_cells sameAs Q7316768.
- Retinal_precursor_cells sameAs m.0r8npc5.
- Retinal_precursor_cells sameAs Q7316768.
- Retinal_precursor_cells wasDerivedFrom Retinal_precursor_cells?oldid=691062047.
- Retinal_precursor_cells depiction Human_eye_cross-sectional_view_grayscale.png.
- Retinal_precursor_cells isPrimaryTopicOf Retinal_precursor_cells.