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- Replication_protein_A abstract "Replication protein A (RPA) is a protein that binds to single-stranded DNA in eukaryotic cells. During DNA replication, RPA prevents single-stranded DNA (ssDNA) from winding back on itself or from forming secondary structures. This keeps DNA unwound for the polymerase to replicate it. RPA also binds to ssDNA during the initial phase of homologous recombination, an important process in DNA repair and prophase I of meiosis. Hypersensitivity to DNA damaging agents can be caused by mutations in the RPA gene. Like its role in DNA replication, this keeps ssDNA from binding to itself (self-complementizing) so that the resulting nucleoprotein filament can then be bound by Rad51 and its cofactors.RPA also binds to DNA during the Nucleotide Excision Repair process. This binding stabilizes the repair complex during the repair process.A bacterial homolog is called single-strand binding protein (SSB).".
- Replication_protein_A symbol "RPA_C".
- Replication_protein_A wikiPageID "14664948".
- Replication_protein_A wikiPageLength "2517".
- Replication_protein_A wikiPageOutDegree "12".
- Replication_protein_A wikiPageRevisionID "703038697".
- Replication_protein_A wikiPageWikiLink Category:Genetics.
- Replication_protein_A wikiPageWikiLink DNA.
- Replication_protein_A wikiPageWikiLink DNA_repair.
- Replication_protein_A wikiPageWikiLink DNA_replication.
- Replication_protein_A wikiPageWikiLink Eukaryote.
- Replication_protein_A wikiPageWikiLink Homologous_recombination.
- Replication_protein_A wikiPageWikiLink Meiosis.
- Replication_protein_A wikiPageWikiLink Nucleoprotein.
- Replication_protein_A wikiPageWikiLink Protein.
- Replication_protein_A wikiPageWikiLink RAD51.
- Replication_protein_A wikiPageWikiLink Single-stranded_binding_protein.
- Replication_protein_A wikiPageWikiLinkText "RPA".
- Replication_protein_A wikiPageWikiLinkText "Replication Protein A".
- Replication_protein_A wikiPageWikiLinkText "Replication protein A".
- Replication_protein_A wikiPageWikiLinkText "replication protein A (RPA)".
- Replication_protein_A wikiPageWikiLinkText "replication protein A".
- Replication_protein_A interpro "IPR014892".
- Replication_protein_A name "Replication protein A C terminal".
- Replication_protein_A pfam "PF08784".
- Replication_protein_A symbol "RPA_C".
- Replication_protein_A wikiPageUsesTemplate Template:DNA_repair.
- Replication_protein_A wikiPageUsesTemplate Template:DNA_replication.
- Replication_protein_A wikiPageUsesTemplate Template:Genetics-stub.
- Replication_protein_A wikiPageUsesTemplate Template:PDB.
- Replication_protein_A wikiPageUsesTemplate Template:Pfam_box.
- Replication_protein_A wikiPageUsesTemplate Template:Reflist.
- Replication_protein_A subject Category:Genetics.
- Replication_protein_A hypernym Protein.
- Replication_protein_A type Biomolecule.
- Replication_protein_A type Protein.
- Replication_protein_A type Thing.
- Replication_protein_A type Q206229.
- Replication_protein_A type Q8054.
- Replication_protein_A comment "Replication protein A (RPA) is a protein that binds to single-stranded DNA in eukaryotic cells. During DNA replication, RPA prevents single-stranded DNA (ssDNA) from winding back on itself or from forming secondary structures. This keeps DNA unwound for the polymerase to replicate it. RPA also binds to ssDNA during the initial phase of homologous recombination, an important process in DNA repair and prophase I of meiosis.".
- Replication_protein_A label "Replication protein A".
- Replication_protein_A sameAs Q2565234.
- Replication_protein_A sameAs Proteína_de_replicación_A.
- Replication_protein_A sameAs Protéine_de_Réplication_A.
- Replication_protein_A sameAs m.03gscpp.
- Replication_protein_A sameAs Репликативный_белок_А.
- Replication_protein_A sameAs Replikacioni_protein_A.
- Replication_protein_A sameAs RPA.
- Replication_protein_A sameAs Q2565234.
- Replication_protein_A wasDerivedFrom Replication_protein_A?oldid=703038697.
- Replication_protein_A isPrimaryTopicOf Replication_protein_A.