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- Rel_homology_domain abstract "The Rel homology domain (RHD) is a protein domain found in a family of eukaryotic transcription factors, which includes NF-κB, NFAT, among others. Some of these transcription factors appear to form multi-protein DNA-bound complexes. Phosphorylation of the RHD appears to play a role in the regulation of some of these transcription factors, acting to modulate the expression of their target genes. The RHD is composed of two immunoglobulin-like beta barrel subdomains that grip the DNA in the major groove. The N-terminal specificity domain resembles the core domain of the p53 transcription factor, and contains a recognition loop that interacts with DNA bases. The C-terminal dimerization domain contains the site for interaction with I-kappaB.".
- Rel_homology_domain symbol "RHD".
- Rel_homology_domain thumbnail 1SVC.png?width=300.
- Rel_homology_domain wikiPageID "20780554".
- Rel_homology_domain wikiPageLength "2706".
- Rel_homology_domain wikiPageOutDegree "14".
- Rel_homology_domain wikiPageRevisionID "689086436".
- Rel_homology_domain wikiPageWikiLink Antibody.
- Rel_homology_domain wikiPageWikiLink Beta_barrel.
- Rel_homology_domain wikiPageWikiLink C-terminus.
- Rel_homology_domain wikiPageWikiLink Category:Protein_domains.
- Rel_homology_domain wikiPageWikiLink DNA.
- Rel_homology_domain wikiPageWikiLink IκBα.
- Rel_homology_domain wikiPageWikiLink N-terminus.
- Rel_homology_domain wikiPageWikiLink NF-κB.
- Rel_homology_domain wikiPageWikiLink NFAT.
- Rel_homology_domain wikiPageWikiLink NFKB1.
- Rel_homology_domain wikiPageWikiLink P53.
- Rel_homology_domain wikiPageWikiLink Phosphorylation.
- Rel_homology_domain wikiPageWikiLink Protein_domain.
- Rel_homology_domain wikiPageWikiLink Transcription_factor.
- Rel_homology_domain wikiPageWikiLinkText "RHD".
- Rel_homology_domain wikiPageWikiLinkText "Rel homology domain".
- Rel_homology_domain wikiPageWikiLinkText "Rel homology region".
- Rel_homology_domain caption "Top view of the crystallographic structure of a homodimer of the NFKB1 protein bound to DNA .".
- Rel_homology_domain cdd "cd07827".
- Rel_homology_domain interpro "IPR011539".
- Rel_homology_domain name "Rel homology domain".
- Rel_homology_domain pdb ", , , , , , , , , , ,, , , , , , , , , , ,, ,".
- Rel_homology_domain pfam "PF00554".
- Rel_homology_domain prosite "PDOC00924".
- Rel_homology_domain scop "1".
- Rel_homology_domain symbol "RHD".
- Rel_homology_domain wikiPageUsesTemplate Template:InterPro_content.
- Rel_homology_domain wikiPageUsesTemplate Template:PDB2.
- Rel_homology_domain wikiPageUsesTemplate Template:Pfam_box.
- Rel_homology_domain wikiPageUsesTemplate Template:Protein-stub.
- Rel_homology_domain wikiPageUsesTemplate Template:Reflist.
- Rel_homology_domain wikiPageUsesTemplate Template:Transcription_factors.
- Rel_homology_domain subject Category:Protein_domains.
- Rel_homology_domain hypernym Domain.
- Rel_homology_domain type Biomolecule.
- Rel_homology_domain type Protein.
- Rel_homology_domain type Chemical.
- Rel_homology_domain type Domain.
- Rel_homology_domain type Thing.
- Rel_homology_domain type Q206229.
- Rel_homology_domain type Q8054.
- Rel_homology_domain comment "The Rel homology domain (RHD) is a protein domain found in a family of eukaryotic transcription factors, which includes NF-κB, NFAT, among others. Some of these transcription factors appear to form multi-protein DNA-bound complexes. Phosphorylation of the RHD appears to play a role in the regulation of some of these transcription factors, acting to modulate the expression of their target genes.".
- Rel_homology_domain label "Rel homology domain".
- Rel_homology_domain sameAs Q7310674.
- Rel_homology_domain sameAs m.056jq4n.
- Rel_homology_domain sameAs Q7310674.
- Rel_homology_domain wasDerivedFrom Rel_homology_domain?oldid=689086436.
- Rel_homology_domain depiction 1SVC.png.
- Rel_homology_domain isPrimaryTopicOf Rel_homology_domain.