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- RNase_MRP abstract "RNase MRP (also called RMRP) is an enzymatically active ribonucleoprotein with two distinct roles in eukaryotes. RNAse MRP stands for RNAse for mitochondrial RNA processing. In mitochondria it plays a direct role in the initiation of mitochondrial DNA replication. In the nucleus it is involved in precursor rRNA processing, where it cleaves the internal transcribed spacer 1 between 18S and 5.8S rRNAs. Despite distinct functions, RNase MRP has been shown to be evolutionarily related to RNase P. Like eukaryotic RNase P, RNase MRP is not catalytically active without associated protein subunits.Mutations in the RNA component of RNase MRP cause cartilage-hair hypoplasia, a pleiotropic human disease. Responsible for this disease is a mutation in the RNase MRP RNA gene (RMRP), a non-coding RNA gene. RMRP was the first non-coding nuclear RNA gene found to cause disease.".
- RNase_MRP thumbnail RF00030.jpg?width=300.
- RNase_MRP wikiPageID "11243833".
- RNase_MRP wikiPageLength "15146".
- RNase_MRP wikiPageOutDegree "74".
- RNase_MRP wikiPageRevisionID "697709498".
- RNase_MRP wikiPageWikiLink 5-3_exoribonuclease_1.
- RNase_MRP wikiPageWikiLink Active_site.
- RNase_MRP wikiPageWikiLink Biomolecular_structure.
- RNase_MRP wikiPageWikiLink Bond_cleavage.
- RNase_MRP wikiPageWikiLink Cartilage–hair_hypoplasia.
- RNase_MRP wikiPageWikiLink Catalysis.
- RNase_MRP wikiPageWikiLink Category:RNA_splicing.
- RNase_MRP wikiPageWikiLink Category:Ribozymes.
- RNase_MRP wikiPageWikiLink Cell_nucleus.
- RNase_MRP wikiPageWikiLink Conserved_sequence.
- RNase_MRP wikiPageWikiLink Cyclin_B2.
- RNase_MRP wikiPageWikiLink D-loop_replication.
- RNase_MRP wikiPageWikiLink Dominance_(genetics).
- RNase_MRP wikiPageWikiLink Dwarfism.
- RNase_MRP wikiPageWikiLink Dysplasia.
- RNase_MRP wikiPageWikiLink Enzyme_catalysis.
- RNase_MRP wikiPageWikiLink Eosinophilia.
- RNase_MRP wikiPageWikiLink Erythroderma.
- RNase_MRP wikiPageWikiLink Eukaryote.
- RNase_MRP wikiPageWikiLink Exoribonuclease.
- RNase_MRP wikiPageWikiLink Gene.
- RNase_MRP wikiPageWikiLink Gene_duplication.
- RNase_MRP wikiPageWikiLink Hypotrichosis.
- RNase_MRP wikiPageWikiLink Immunodeficiency.
- RNase_MRP wikiPageWikiLink Insertion_(genetics).
- RNase_MRP wikiPageWikiLink Internal_transcribed_spacer.
- RNase_MRP wikiPageWikiLink Metaphyseal_dysplasia.
- RNase_MRP wikiPageWikiLink Metaphysis.
- RNase_MRP wikiPageWikiLink Minimal_change_disease.
- RNase_MRP wikiPageWikiLink Mitochondrion.
- RNase_MRP wikiPageWikiLink Mitosis.
- RNase_MRP wikiPageWikiLink Mutant.
- RNase_MRP wikiPageWikiLink Mutation.
- RNase_MRP wikiPageWikiLink Nucleic_acid_tertiary_structure.
- RNase_MRP wikiPageWikiLink Omenn_syndrome.
- RNase_MRP wikiPageWikiLink Phylogenetic_tree.
- RNase_MRP wikiPageWikiLink Plasmid.
- RNase_MRP wikiPageWikiLink Pleiotropy.
- RNase_MRP wikiPageWikiLink Post-transcriptional_modification.
- RNase_MRP wikiPageWikiLink Preribosomal_RNA.
- RNase_MRP wikiPageWikiLink Prokaryote.
- RNase_MRP wikiPageWikiLink Promoter_(genetics).
- RNase_MRP wikiPageWikiLink Protein_secondary_structure.
- RNase_MRP wikiPageWikiLink Protein_subunit.
- RNase_MRP wikiPageWikiLink RMRP.
- RNase_MRP wikiPageWikiLink RNA.
- RNase_MRP wikiPageWikiLink Reaction_intermediate.
- RNase_MRP wikiPageWikiLink Reduplication.
- RNase_MRP wikiPageWikiLink Ribonuclease.
- RNase_MRP wikiPageWikiLink Ribonuclease_P.
- RNase_MRP wikiPageWikiLink Ribonucleoprotein.
- RNase_MRP wikiPageWikiLink Ribosomal_RNA.
- RNase_MRP wikiPageWikiLink Ribozyme.
- RNase_MRP wikiPageWikiLink TATA_box.
- RNase_MRP wikiPageWikiLink Transfer_RNA.
- RNase_MRP wikiPageWikiLink File:RNA_MRP_Regulation_of_Cell_Cycle.png.
- RNase_MRP wikiPageWikiLink File:RNase_MRP_Cleavage_Role_in_Diagram_of_pre-rRNA_Processing_Pathway.png.
- RNase_MRP wikiPageWikiLink File:RNase_MRP_RNA_-_Secondary_AA_(structure).png.
- RNase_MRP wikiPageWikiLinkText "RNase MRP".
- RNase_MRP wikiPageWikiLinkText "Ribonuclease MRP".
- RNase_MRP caption "Predicted secondary structure and sequence conservation of RNase_MRP".
- RNase_MRP id "RF00030".
- RNase_MRP name "RNase MRP".
- RNase_MRP rfam "RF00030".
- RNase_MRP rnaType Gene.
- RNase_MRP rnaType Ribozyme.
- RNase_MRP symbol "RNase_MRP".
- RNase_MRP taxDomain Eukaryote.
- RNase_MRP wikiPageUsesTemplate Template:Esterases.
- RNase_MRP wikiPageUsesTemplate Template:GO.
- RNase_MRP wikiPageUsesTemplate Template:Infobox_rfam.
- RNase_MRP wikiPageUsesTemplate Template:MeshName.
- RNase_MRP wikiPageUsesTemplate Template:Reflist.
- RNase_MRP wikiPageUsesTemplate Template:Rfam.
- RNase_MRP wikiPageUsesTemplate Template:SO.
- RNase_MRP subject Category:RNA_splicing.
- RNase_MRP subject Category:Ribozymes.
- RNase_MRP comment "RNase MRP (also called RMRP) is an enzymatically active ribonucleoprotein with two distinct roles in eukaryotes. RNAse MRP stands for RNAse for mitochondrial RNA processing. In mitochondria it plays a direct role in the initiation of mitochondrial DNA replication. In the nucleus it is involved in precursor rRNA processing, where it cleaves the internal transcribed spacer 1 between 18S and 5.8S rRNAs. Despite distinct functions, RNase MRP has been shown to be evolutionarily related to RNase P.".
- RNase_MRP label "RNase MRP".
- RNase_MRP sameAs Q7277299.
- RNase_MRP sameAs m.02r4x2s.
- RNase_MRP sameAs Q7277299.
- RNase_MRP wasDerivedFrom RNase_MRP?oldid=697709498.
- RNase_MRP depiction RF00030.jpg.
- RNase_MRP isPrimaryTopicOf RNase_MRP.