Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/RB-64> ?p ?o }
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- RB-64 abstract "RB-64 or 22-thiocyanatosalvinorin A is a semi-synthetic salvonorin derivative and a κ-opioid receptor (KOR) agonist which is used in scientific research. Its most remarkable property is its biased activity in signal transduction in favour of G protein versus β-arrestin-2, a phenomenon which is called functional selectivity or biased agonism. RB-64 has a bias factor of 96 and is analgesic with fewer of the prototypical side-effects associated with unbiased KOR agonists. The analgesia-like effect is long-lasting. Compared with unbiased agonists RB-64 evokes considerably less receptor internalisation.".
- RB-64 atcPrefix "none".
- RB-64 iupacName "Methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-9-(2-thiocyanatoacetyl)oxy-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate".
- RB-64 pubchem "73347341".
- RB-64 thumbnail 22-Thiocyanatosalvinorin_A.png?width=300.
- RB-64 wikiPageID "44270518".
- RB-64 wikiPageLength "3158".
- RB-64 wikiPageOutDegree "18".
- RB-64 wikiPageRevisionID "699215346".
- RB-64 wikiPageWikiLink Agonist.
- RB-64 wikiPageWikiLink Analgesic.
- RB-64 wikiPageWikiLink Arrestin_beta_2.
- RB-64 wikiPageWikiLink Category:Biased_ligands.
- RB-64 wikiPageWikiLink Category:Kappa_agonists.
- RB-64 wikiPageWikiLink Category:Kappa_antagonists.
- RB-64 wikiPageWikiLink Category:Synthetic_opioids.
- RB-64 wikiPageWikiLink Endocytosis.
- RB-64 wikiPageWikiLink Functional_selectivity.
- RB-64 wikiPageWikiLink G_protein.
- RB-64 wikiPageWikiLink Herkinorin.
- RB-64 wikiPageWikiLink Nalfurafine.
- RB-64 wikiPageWikiLink Salvinorin_A.
- RB-64 wikiPageWikiLink Salvinorin_B_methoxymethyl_ether.
- RB-64 wikiPageWikiLink Signal_transduction.
- RB-64 wikiPageWikiLink Κ-opioid_receptor.
- RB-64 wikiPageWikiLinkText "RB-64".
- RB-64 atcPrefix "none".
- RB-64 c "24".
- RB-64 h "27".
- RB-64 iupacName "Methyl -2--6a,10b-dimethyl-4,10-dioxo-9-oxy-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate".
- RB-64 legalStatus "Legal/Uncontrolled".
- RB-64 molecularWeight "489.54".
- RB-64 n "1".
- RB-64 o "8".
- RB-64 pubchem "73347341".
- RB-64 s "1".
- RB-64 smiles "C[C@@]12CC[C@H]3CO[C@@H]C4=COC=C4".
- RB-64 stdinchi "1".
- RB-64 stdinchikey "AZPUAKGNQXURGA-ZWLNRFIDSA-N".
- RB-64 width "200".
- RB-64 wikiPageUsesTemplate Template:Chemspidercite.
- RB-64 wikiPageUsesTemplate Template:Cite_journal.
- RB-64 wikiPageUsesTemplate Template:Drugbox.
- RB-64 wikiPageUsesTemplate Template:Ebicite.
- RB-64 wikiPageUsesTemplate Template:Opioidergics.
- RB-64 wikiPageUsesTemplate Template:Pharmacology-stub.
- RB-64 wikiPageUsesTemplate Template:Stdinchicite.
- RB-64 subject Category:Biased_ligands.
- RB-64 subject Category:Kappa_agonists.
- RB-64 subject Category:Kappa_antagonists.
- RB-64 subject Category:Synthetic_opioids.
- RB-64 type ChemicalSubstance.
- RB-64 type Drug.
- RB-64 type ChemicalObject.
- RB-64 type Thing.
- RB-64 type Q8386.
- RB-64 comment "RB-64 or 22-thiocyanatosalvinorin A is a semi-synthetic salvonorin derivative and a κ-opioid receptor (KOR) agonist which is used in scientific research. Its most remarkable property is its biased activity in signal transduction in favour of G protein versus β-arrestin-2, a phenomenon which is called functional selectivity or biased agonism. RB-64 has a bias factor of 96 and is analgesic with fewer of the prototypical side-effects associated with unbiased KOR agonists.".
- RB-64 label "RB-64".
- RB-64 sameAs Q21098830.
- RB-64 sameAs m.0127fd2k.
- RB-64 sameAs Q21098830.
- RB-64 wasDerivedFrom RB-64?oldid=699215346.
- RB-64 depiction 22-Thiocyanatosalvinorin_A.png.
- RB-64 isPrimaryTopicOf RB-64.