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- Pyr1 abstract "Pyr1 (LIMINIB) is an organic compound composed of carbon, hydrogen, oxygen and nitrogen that inhibits the enzyme LIM kinase.It was recently discovered by the Cure and Inserm Institute, CNRS and CEA, in collaboration with British and Australian investigators. The studies in vitro and with animals, published in Cancer Research, prove that this molecule has a completely new mechanism of action that could be used against chemotherapy resistant cells, providing a new alternative treatment to cancer that does not have major side effects.Pyr1 reversibly stabilizes microtubules, blocks actin microfilament dynamics and inhibits cell motility in vitro. These characteristics confer not only anticancer properties but also the capacity to prevent metastasis to the molecule.".
- Pyr1 iupacName "5,11-Dimethyl-1-oxo-2,6-dihydro-1H-pyrido[4,3-b]carbazol-9-yl benzoate".
- Pyr1 thumbnail Pyr1.svg?width=300.
- Pyr1 wikiPageExternalLink L_Lafanechere.pdf.
- Pyr1 wikiPageID "37652035".
- Pyr1 wikiPageLength "6083".
- Pyr1 wikiPageOutDegree "25".
- Pyr1 wikiPageRevisionID "670421703".
- Pyr1 wikiPageWikiLink Actin.
- Pyr1 wikiPageWikiLink Apoptosis.
- Pyr1 wikiPageWikiLink Benzene.
- Pyr1 wikiPageWikiLink Bone_marrow_suppression.
- Pyr1 wikiPageWikiLink Cancer_Research_(journal).
- Pyr1 wikiPageWikiLink Category:Carbazoles.
- Pyr1 wikiPageWikiLink Cell_migration.
- Pyr1 wikiPageWikiLink Chromosome.
- Pyr1 wikiPageWikiLink Cofilin.
- Pyr1 wikiPageWikiLink Enzyme.
- Pyr1 wikiPageWikiLink Enzyme_inhibitor.
- Pyr1 wikiPageWikiLink Ketone.
- Pyr1 wikiPageWikiLink LIMK1.
- Pyr1 wikiPageWikiLink Metastasis.
- Pyr1 wikiPageWikiLink Methyl_group.
- Pyr1 wikiPageWikiLink Microtubule.
- Pyr1 wikiPageWikiLink Mitosis.
- Pyr1 wikiPageWikiLink Neurotoxicity.
- Pyr1 wikiPageWikiLink Organic_compound.
- Pyr1 wikiPageWikiLink Phosphorylation.
- Pyr1 wikiPageWikiLink Spindle_apparatus.
- Pyr1 wikiPageWikiLink Tubulin.
- Pyr1 wikiPageWikiLink Xenotransplantation.
- Pyr1 wikiPageWikiLink File:ESQUEMA1.JPG.
- Pyr1 wikiPageWikiLink File:ESQUEMA2.JPG.
- Pyr1 wikiPageWikiLinkText "Pyr1".
- Pyr1 imagefile "Pyr1.svg".
- Pyr1 imagesize "200".
- Pyr1 iupacname "511".
- Pyr1 othernames "LIMINIB".
- Pyr1 wikiPageUsesTemplate Template:Cascite.
- Pyr1 wikiPageUsesTemplate Template:Chembox.
- Pyr1 wikiPageUsesTemplate Template:Chembox_Hazards.
- Pyr1 wikiPageUsesTemplate Template:Chembox_Identifiers.
- Pyr1 wikiPageUsesTemplate Template:Chembox_Properties.
- Pyr1 wikiPageUsesTemplate Template:Orphan.
- Pyr1 wikiPageUsesTemplate Template:Reflist.
- Pyr1 subject Category:Carbazoles.
- Pyr1 hypernym Compound.
- Pyr1 type ChemicalCompound.
- Pyr1 type ChemicalSubstance.
- Pyr1 type Chemical.
- Pyr1 type Heterocycle.
- Pyr1 type ChemicalObject.
- Pyr1 type Thing.
- Pyr1 type Q11173.
- Pyr1 comment "Pyr1 (LIMINIB) is an organic compound composed of carbon, hydrogen, oxygen and nitrogen that inhibits the enzyme LIM kinase.It was recently discovered by the Cure and Inserm Institute, CNRS and CEA, in collaboration with British and Australian investigators.".
- Pyr1 label "Pyr1".
- Pyr1 sameAs Q7263194.
- Pyr1 sameAs Pyr1.
- Pyr1 sameAs m.0ndhq01.
- Pyr1 sameAs Pir1.
- Pyr1 sameAs Pir1.
- Pyr1 sameAs Q7263194.
- Pyr1 wasDerivedFrom Pyr1?oldid=670421703.
- Pyr1 depiction Pyr1.svg.
- Pyr1 isPrimaryTopicOf Pyr1.