Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Protein_design> ?p ?o }
- Protein_design abstract "This article refers to rational protein design. For the broader engineering of proteins see protein engineering.Protein design is the rational design of new protein molecules to fold to a target protein structure, with the ultimate goal of designing novel function and/or behavior. Proteins can be designed from scratch (de novo design) or by making calculated variations on a known protein structure and its sequence (known as protein redesign). Rational protein design approaches make protein-sequence predictions that will fold to specific structures. These predicted sequences can then be validated experimentally through methods such as peptide synthesis, site-directed mutagenesis, or artificial gene synthesis.Rational protein design dates back to the mid-1970s, although initial protein design approaches were based mostly on sequence composition and did not account for specific interactions between side-chains at the atomic level. Recently, however, improvements in molecular force fields, protein design algorithms, and structural bioinformatics, such as libraries of amino acid conformations, have enabled the development of advanced computational protein design tools. These computational tools can make complex calculations on protein energetics and flexibility, and perform searches over enormous configuration spaces, which would be unfeasible to perform manually. Thanks to the development of computational protein design programs and important successes in the field (e.g., see examples below), rational protein design has become one of the most important tools in protein engineering.".
- Protein_design wikiPageExternalLink rosettadesign.med.unc.edu.
- Protein_design wikiPageExternalLink abstract.
- Protein_design wikiPageExternalLink protdes.html.
- Protein_design wikiPageExternalLink osprey.php.
- Protein_design wikiPageExternalLink www.dezyme.com.
- Protein_design wikiPageExternalLink www.proteinwisdom.org.
- Protein_design wikiPageExternalLink www.sharp-n.com.
- Protein_design wikiPageID "1581752".
- Protein_design wikiPageLength "72285".
- Protein_design wikiPageOutDegree "123".
- Protein_design wikiPageRevisionID "706018515".
- Protein_design wikiPageWikiLink A*_search_algorithm.
- Protein_design wikiPageWikiLink AMBER.
- Protein_design wikiPageWikiLink Abalone_(molecular_mechanics).
- Protein_design wikiPageWikiLink Aldol_reaction.
- Protein_design wikiPageWikiLink Alzheimers_disease.
- Protein_design wikiPageWikiLink Amino_acid.
- Protein_design wikiPageWikiLink Artificial_gene_synthesis.
- Protein_design wikiPageWikiLink BZIP_domain.
- Protein_design wikiPageWikiLink Barrier_function.
- Protein_design wikiPageWikiLink Belief_propagation.
- Protein_design wikiPageWikiLink Bioinformatics.
- Protein_design wikiPageWikiLink Biological_engineering.
- Protein_design wikiPageWikiLink Biomedicine.
- Protein_design wikiPageWikiLink Biosensor.
- Protein_design wikiPageWikiLink Boltzmann_constant.
- Protein_design wikiPageWikiLink Branch_and_bound.
- Protein_design wikiPageWikiLink Branch_and_cut.
- Protein_design wikiPageWikiLink Bruce_Donald.
- Protein_design wikiPageWikiLink CHARMM.
- Protein_design wikiPageWikiLink CPLEX.
- Protein_design wikiPageWikiLink Category:Protein_engineering.
- Protein_design wikiPageWikiLink Category:Protein_structure.
- Protein_design wikiPageWikiLink Cofactor_(biochemistry).
- Protein_design wikiPageWikiLink Coiled_coil.
- Protein_design wikiPageWikiLink Collagen.
- Protein_design wikiPageWikiLink Configuration_space.
- Protein_design wikiPageWikiLink Conformational_isomerism.
- Protein_design wikiPageWikiLink Cystic_fibrosis.
- Protein_design wikiPageWikiLink DDT.
- Protein_design wikiPageWikiLink David_Baker_(biochemist).
- Protein_design wikiPageWikiLink Dead-end_elimination.
- Protein_design wikiPageWikiLink Diels–Alder_reaction.
- Protein_design wikiPageWikiLink Dihedral_angle.
- Protein_design wikiPageWikiLink Directed_evolution.
- Protein_design wikiPageWikiLink Duality_(optimization).
- Protein_design wikiPageWikiLink Elastin.
- Protein_design wikiPageWikiLink Electrostatics.
- Protein_design wikiPageWikiLink Enzyme.
- Protein_design wikiPageWikiLink Enzyme_catalysis.
- Protein_design wikiPageWikiLink Folding_funnel.
- Protein_design wikiPageWikiLink Force_field_(chemistry).
- Protein_design wikiPageWikiLink Globular_protein.
- Protein_design wikiPageWikiLink Gramicidin_S.
- Protein_design wikiPageWikiLink HIV.
- Protein_design wikiPageWikiLink Heuristic_(computer_science).
- Protein_design wikiPageWikiLink In_vivo.
- Protein_design wikiPageWikiLink John_Lennard-Jones.
- Protein_design wikiPageWikiLink Linear_programming.
- Protein_design wikiPageWikiLink Linear_programming_relaxation.
- Protein_design wikiPageWikiLink List_of_protein_structure_prediction_software.
- Protein_design wikiPageWikiLink List_of_software_for_molecular_mechanics_modeling.
- Protein_design wikiPageWikiLink Membrane_protein.
- Protein_design wikiPageWikiLink Molecular_design_software.
- Protein_design wikiPageWikiLink Molecular_dynamics.
- Protein_design wikiPageWikiLink Molecular_mechanics.
- Protein_design wikiPageWikiLink Mutation.
- Protein_design wikiPageWikiLink NP-hardness.
- Protein_design wikiPageWikiLink Native_state.
- Protein_design wikiPageWikiLink Nicotinamide_adenine_dinucleotide.
- Protein_design wikiPageWikiLink Nicotinamide_adenine_dinucleotide_phosphate.
- Protein_design wikiPageWikiLink Nonribosomal_peptide.
- Protein_design wikiPageWikiLink Nuclear_magnetic_resonance.
- Protein_design wikiPageWikiLink OPLS.
- Protein_design wikiPageWikiLink P21-activated_kinases.
- Protein_design wikiPageWikiLink P53.
- Protein_design wikiPageWikiLink Peptide_synthesis.
- Protein_design wikiPageWikiLink Peter_S._Kim.
- Protein_design wikiPageWikiLink Phenylalanine.
- Protein_design wikiPageWikiLink Protein.
- Protein_design wikiPageWikiLink Protein_design.
- Protein_design wikiPageWikiLink Protein_domain.
- Protein_design wikiPageWikiLink Protein_engineering.
- Protein_design wikiPageWikiLink Protein_folding.
- Protein_design wikiPageWikiLink Protein_primary_structure.
- Protein_design wikiPageWikiLink Protein_structure.
- Protein_design wikiPageWikiLink Protein_structure_prediction.
- Protein_design wikiPageWikiLink Protein_tertiary_structure.
- Protein_design wikiPageWikiLink Protein–protein_interaction.
- Protein_design wikiPageWikiLink Rational_design.
- Protein_design wikiPageWikiLink Run_time_(program_lifecycle_phase).
- Protein_design wikiPageWikiLink Scleroprotein.
- Protein_design wikiPageWikiLink Sequence_space_(evolution).
- Protein_design wikiPageWikiLink Simplex_algorithm.
- Protein_design wikiPageWikiLink Simulated_annealing.
- Protein_design wikiPageWikiLink Site-directed_mutagenesis.
- Protein_design wikiPageWikiLink Statistical_potential.
- Protein_design wikiPageWikiLink Structural_bioinformatics.
- Protein_design wikiPageWikiLink Structural_flexibility.