Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Protectin_D1> ?p ?o }
- Protectin_D1 abstract "Protectin D1 also known as neuroprotectin D1 (when it acts in the nervous system) and abbreviated most commonly as PD1 or NPD1 is an organic biomolecule with strong anti-inflammatory, anti-apoptotic and neuroprotective activity. PD1 is an aliphatic acyclic alkene with two hydroxyl groups at the 10 and 17 carbon positions and one carboxylic acid group at the one carbon position.Specifically, PD1 is an endogenous stereoselective lipid mediator classified as an autocoid protectin. Autacoids are enzymatically derived chemical mediators with distinct biological activities and molecular structures. Protectins are signaling molecules that are produced enzymatically from unsaturated fatty acids. Their molecular structure is characterized by the presence of a conjugated system of double bonds. PD1, like other protectins, is produced by the oxygenation of the ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) and it is found in many tissues, such as the retina, the lungs and the nervous system.PD1 has a significant role as an anti-inflammatory, anti-apoptotic and neuroprotective molecule. Studies in Alzheimer's disease animal models, in stroke patients and in human retina pigment epithelial cells (RPE) have shown that PD1 can potentially reduce inflammation induced by oxidative stress and inhibit the pro-apoptotic signal, thereby preventing cellular degeneration. Finally, recent studies examining the pathogenicity of influenza viruses, including the avian flu (H5N1), have suggested that PD1 can potentially halt the proliferation of the virus, thus protecting respiratory cells from lethal viral infections.".
- Protectin_D1 iupacName "(4Z,7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid".
- Protectin_D1 thumbnail Protectin_D1.svg?width=300.
- Protectin_D1 wikiPageExternalLink FDB023215.
- Protectin_D1 wikiPageExternalLink summary.cgi?cid=16042541.
- Protectin_D1 wikiPageExternalLink Chemical-Structure.13171083.html?rid=c365736b-0463-4d5a-8faa-2b40f8f6eb98.
- Protectin_D1 wikiPageExternalLink HMDB03689.
- Protectin_D1 wikiPageExternalLink LMSDRecord.php?LMID=LMFA04000011.
- Protectin_D1 wikiPageID "42777505".
- Protectin_D1 wikiPageLength "18840".
- Protectin_D1 wikiPageOutDegree "78".
- Protectin_D1 wikiPageRevisionID "701500066".
- Protectin_D1 wikiPageWikiLink Acetylene.
- Protectin_D1 wikiPageWikiLink Aliphatic_compound.
- Protectin_D1 wikiPageWikiLink Alkene.
- Protectin_D1 wikiPageWikiLink Alkyne.
- Protectin_D1 wikiPageWikiLink Alzheimers_disease.
- Protectin_D1 wikiPageWikiLink Amyloid_beta.
- Protectin_D1 wikiPageWikiLink Amyloid_precursor_protein.
- Protectin_D1 wikiPageWikiLink Apoptosis.
- Protectin_D1 wikiPageWikiLink Apoptosome.
- Protectin_D1 wikiPageWikiLink Autacoid.
- Protectin_D1 wikiPageWikiLink Bcl-2.
- Protectin_D1 wikiPageWikiLink C-terminus.
- Protectin_D1 wikiPageWikiLink Caspase_3.
- Protectin_D1 wikiPageWikiLink Category:Alkenes.
- Protectin_D1 wikiPageWikiLink Category:Docosanoids.
- Protectin_D1 wikiPageWikiLink Category:Fatty_acids.
- Protectin_D1 wikiPageWikiLink Category:Lipids.
- Protectin_D1 wikiPageWikiLink Conjugated_system.
- Protectin_D1 wikiPageWikiLink Convergent_synthesis.
- Protectin_D1 wikiPageWikiLink Cytochrome_c.
- Protectin_D1 wikiPageWikiLink Cytosol.
- Protectin_D1 wikiPageWikiLink Dephosphorylation.
- Protectin_D1 wikiPageWikiLink Diethylamine.
- Protectin_D1 wikiPageWikiLink Diol.
- Protectin_D1 wikiPageWikiLink Dioxygenase.
- Protectin_D1 wikiPageWikiLink Docosahexaenoic_acid.
- Protectin_D1 wikiPageWikiLink Enzymatic_hydrolysis.
- Protectin_D1 wikiPageWikiLink Ester.
- Protectin_D1 wikiPageWikiLink Heme.
- Protectin_D1 wikiPageWikiLink Hydroboration.
- Protectin_D1 wikiPageWikiLink Inflammation.
- Protectin_D1 wikiPageWikiLink Influenza.
- Protectin_D1 wikiPageWikiLink Interleukin_4.
- Protectin_D1 wikiPageWikiLink Lindlar_catalyst.
- Protectin_D1 wikiPageWikiLink Lipoxygenase.
- Protectin_D1 wikiPageWikiLink Lithium_hydroxide.
- Protectin_D1 wikiPageWikiLink Methanol.
- Protectin_D1 wikiPageWikiLink NF-κB.
- Protectin_D1 wikiPageWikiLink NXF1.
- Protectin_D1 wikiPageWikiLink Neuroglia.
- Protectin_D1 wikiPageWikiLink Neuroprotectin.
- Protectin_D1 wikiPageWikiLink Nuclear_pore.
- Protectin_D1 wikiPageWikiLink Nuclear_transport.
- Protectin_D1 wikiPageWikiLink Nucleoporin.
- Protectin_D1 wikiPageWikiLink Omega-3_fatty_acid.
- Protectin_D1 wikiPageWikiLink Organoboron_chemistry.
- Protectin_D1 wikiPageWikiLink Oxidative_stress.
- Protectin_D1 wikiPageWikiLink Peripheral_blood_mononuclear_cell.
- Protectin_D1 wikiPageWikiLink Peroxisome_proliferator-activated_receptor_gamma.
- Protectin_D1 wikiPageWikiLink Phagocytosis.
- Protectin_D1 wikiPageWikiLink Phospholipase_A2.
- Protectin_D1 wikiPageWikiLink Photoreceptor_cell.
- Protectin_D1 wikiPageWikiLink Prostaglandin.
- Protectin_D1 wikiPageWikiLink Prostaglandin-endoperoxide_synthase_2.
- Protectin_D1 wikiPageWikiLink Protein_dimer.
- Protectin_D1 wikiPageWikiLink Protein_phosphatase_2.
- Protectin_D1 wikiPageWikiLink RNA.
- Protectin_D1 wikiPageWikiLink Retinal_pigment_epithelium.
- Protectin_D1 wikiPageWikiLink Saponification.
- Protectin_D1 wikiPageWikiLink Senile_plaques.
- Protectin_D1 wikiPageWikiLink Serine.
- Protectin_D1 wikiPageWikiLink Silyl_ether.
- Protectin_D1 wikiPageWikiLink Sodium_hydroxide.
- Protectin_D1 wikiPageWikiLink Sonogashira_coupling.
- Protectin_D1 wikiPageWikiLink Stereoselectivity.
- Protectin_D1 wikiPageWikiLink Stereospecificity.
- Protectin_D1 wikiPageWikiLink Substrate_(chemistry).
- Protectin_D1 wikiPageWikiLink T_helper_cell.
- Protectin_D1 wikiPageWikiLink Tetra-n-butylammonium_fluoride.
- Protectin_D1 wikiPageWikiLink Tetrahydrofuran.
- Protectin_D1 wikiPageWikiLink Transcription_factor.
- Protectin_D1 wikiPageWikiLink Ubiquitin.
- Protectin_D1 wikiPageWikiLink Work-up_(chemistry).
- Protectin_D1 wikiPageWikiLink File:Convergent_Stereoselective_Synthesis_of_PD1.jpg.
- Protectin_D1 wikiPageWikiLink File:Laboratory_synthesis_of_Protectin_D1_(PD1).jpg.
- Protectin_D1 wikiPageWikiLink File:Protectin_D1_(PD1)_Biosynthesis.jpg.
- Protectin_D1 wikiPageWikiLinkText "Protectin D1".
- Protectin_D1 wikiPageWikiLinkText "Protectin D1##Functions of PD1".
- Protectin_D1 wikiPageWikiLinkText "protectin D1".
- Protectin_D1 imagefile "Protectin D1.svg".
- Protectin_D1 imagesize "350".
- Protectin_D1 iupacname "-1017".
- Protectin_D1 name "Protectin D1".
- Protectin_D1 othernames "10".
- Protectin_D1 wikiPageUsesTemplate Template:Cascite.
- Protectin_D1 wikiPageUsesTemplate Template:Chembox.
- Protectin_D1 wikiPageUsesTemplate Template:Chembox_Identifiers.
- Protectin_D1 wikiPageUsesTemplate Template:Chembox_Properties.