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- Proinflammatory_cytokine abstract "Proinflammatory cytokines are a specific category of cytokines that are important in cell signaling and promotes systemic inflammation. They are produced predominantly by activated macrophages and are involved in the up-regulation of inflammatory reactions. In contrast to anti-inflammatory cytokines, which promote healing and reduce inflammation, proinflammatory cytokines act to make a disease worse. Functions include neutralizing antibodies, serving as soluble receptors and receptor antagonists, and inhibiting proteases. Proinflammatory cytokines arise from genes that code for the translation of small mediator molecules that induce a response after upregulation. For example, chemokines are a class of genes that are proinflammatory. IL-1, TNF alpha, and chemokines are examples of proinflammatory cytokines.Proinflammatory cytokines work with other important molecules from the immune system, such as neutrophils and leukocytes, in generating an immune response. This proinflammatory cytokine-mediated inflammation generates a collection of gene products in response to a trigger that notices a foreign body. However, excessive amounts of proinflammatory cytokines have been shown to cause detrimental effects, causing chronic systemic elevations in the body. A lack of regulation in the release of these cytokines has been linked to different diseases, such as atherosclerosis and cancers. There are further implications that misregulation of proinflammatory cytokines is also linked to depression and other neurologically related effects to the body[3]. Aging and exercise also play a role in the amount of inflammation produced through the release of proinflammatory cytokines such as tumor necrosis factor alpha (TNF-α). Recent therapies blocking proinflammatory cytokines in order to prevent the attack of these cytokines against our own bodies.It is important that the regulation between proinflammatory and anti-inflammatory cytokines stay balanced, as that could alter one's susceptibility to a disease.".
- Proinflammatory_cytokine wikiPageID "20345288".
- Proinflammatory_cytokine wikiPageLength "10397".
- Proinflammatory_cytokine wikiPageOutDegree "22".
- Proinflammatory_cytokine wikiPageRevisionID "707971750".
- Proinflammatory_cytokine wikiPageWikiLink Atherosclerosis.
- Proinflammatory_cytokine wikiPageWikiLink Category:Cytokines.
- Proinflammatory_cytokine wikiPageWikiLink Cystic_fibrosis.
- Proinflammatory_cytokine wikiPageWikiLink Death.
- Proinflammatory_cytokine wikiPageWikiLink Fever.
- Proinflammatory_cytokine wikiPageWikiLink Graft-versus-host_disease.
- Proinflammatory_cytokine wikiPageWikiLink Histone_deacetylase_inhibitor.
- Proinflammatory_cytokine wikiPageWikiLink IL1B.
- Proinflammatory_cytokine wikiPageWikiLink Inflammation.
- Proinflammatory_cytokine wikiPageWikiLink Inflammatory_bowel_disease.
- Proinflammatory_cytokine wikiPageWikiLink Interleukin_10.
- Proinflammatory_cytokine wikiPageWikiLink Interleukin_6.
- Proinflammatory_cytokine wikiPageWikiLink Nephron.
- Proinflammatory_cytokine wikiPageWikiLink Neutrophil_granulocyte.
- Proinflammatory_cytokine wikiPageWikiLink Potassium.
- Proinflammatory_cytokine wikiPageWikiLink Renal_fibrosis.
- Proinflammatory_cytokine wikiPageWikiLink STAT.
- Proinflammatory_cytokine wikiPageWikiLink Shock_(circulatory).
- Proinflammatory_cytokine wikiPageWikiLink Tumor_necrosis_factor_alpha.
- Proinflammatory_cytokine wikiPageWikiLink White_blood_cell.
- Proinflammatory_cytokine wikiPageWikiLinkText "Proinflammatory cytokine".
- Proinflammatory_cytokine wikiPageWikiLinkText "inflammatory cytokines".
- Proinflammatory_cytokine wikiPageWikiLinkText "pro-inflammatory cytokine".
- Proinflammatory_cytokine wikiPageWikiLinkText "pro-inflammatory".
- Proinflammatory_cytokine wikiPageWikiLinkText "proinflammatory cytokine".
- Proinflammatory_cytokine wikiPageWikiLinkText "proinflammatory".
- Proinflammatory_cytokine wikiPageUsesTemplate Template:Cytokines.
- Proinflammatory_cytokine wikiPageUsesTemplate Template:Immunology-stub.
- Proinflammatory_cytokine wikiPageUsesTemplate Template:Reflist.
- Proinflammatory_cytokine subject Category:Cytokines.
- Proinflammatory_cytokine hypernym Category.
- Proinflammatory_cytokine type TelevisionStation.
- Proinflammatory_cytokine comment "Proinflammatory cytokines are a specific category of cytokines that are important in cell signaling and promotes systemic inflammation. They are produced predominantly by activated macrophages and are involved in the up-regulation of inflammatory reactions. In contrast to anti-inflammatory cytokines, which promote healing and reduce inflammation, proinflammatory cytokines act to make a disease worse.".
- Proinflammatory_cytokine label "Proinflammatory cytokine".
- Proinflammatory_cytokine sameAs Q3491837.
- Proinflammatory_cytokine sameAs سيتوكينات_منشطة_للالتهاب.
- Proinflammatory_cytokine sameAs Cytokiny_prozapalne.
- Proinflammatory_cytokine sameAs m.04_11t2.
- Proinflammatory_cytokine sameAs Proinflamatorni_citokin.
- Proinflammatory_cytokine sameAs Proinflamatorni_citokin.
- Proinflammatory_cytokine sameAs Прозапальні_цитокіни.
- Proinflammatory_cytokine sameAs Q3491837.
- Proinflammatory_cytokine sameAs 促炎性细胞因子.
- Proinflammatory_cytokine wasDerivedFrom Proinflammatory_cytokine?oldid=707971750.
- Proinflammatory_cytokine isPrimaryTopicOf Proinflammatory_cytokine.