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- Polyglutamine_tract abstract "A polyglutamine tract or polyQ tract is a portion of a protein consisting of a sequence of several glutamine units. A tract typically consists of about 10 to a few hundred such units. A multitude of genes, in various eukaryotic species (including humans), contain a number of repetitions of the nucleotide triplet CAG or CAA. When the gene is translated into a protein, each of these triplets gives rise to a glutamine unit, resulting in a polyglutamine tract. Different alleles of such a gene often have different numbers of triplets since the highly repetitive sequence is prone to contraction and expansion. Several inheritable neurodegenerative disorders, the polyglutamine diseases, occur if a mutation causes a polyglutamine tract in a specific gene to become too long. Important examples of polyglutamine diseases are spinocerebellar ataxia and Huntington's disease. It is believed that cells cannot properly dispose of proteins with overlong polyglutamine tracts, which over time leads to damage in nerve cells. The longer the polyglutamine tract, the earlier in life these diseases tend to appear.".
- Polyglutamine_tract wikiPageID "20895673".
- Polyglutamine_tract wikiPageLength "1555".
- Polyglutamine_tract wikiPageOutDegree "19".
- Polyglutamine_tract wikiPageRevisionID "696383191".
- Polyglutamine_tract wikiPageWikiLink Adenosine.
- Polyglutamine_tract wikiPageWikiLink Allele.
- Polyglutamine_tract wikiPageWikiLink Category:Peptides.
- Polyglutamine_tract wikiPageWikiLink Cytidine.
- Polyglutamine_tract wikiPageWikiLink Gene.
- Polyglutamine_tract wikiPageWikiLink Glutamine.
- Polyglutamine_tract wikiPageWikiLink Guanosine.
- Polyglutamine_tract wikiPageWikiLink Huntingtons_disease.
- Polyglutamine_tract wikiPageWikiLink Mutation.
- Polyglutamine_tract wikiPageWikiLink Neurodegeneration.
- Polyglutamine_tract wikiPageWikiLink Neuron.
- Polyglutamine_tract wikiPageWikiLink Nucleotide.
- Polyglutamine_tract wikiPageWikiLink Protein.
- Polyglutamine_tract wikiPageWikiLink Spinocerebellar_ataxia.
- Polyglutamine_tract wikiPageWikiLink Translation_(biology).
- Polyglutamine_tract wikiPageWikiLink Trinucleotide_repeat_disorder.
- Polyglutamine_tract wikiPageWikiLinkText "Excessive repeats".
- Polyglutamine_tract wikiPageWikiLinkText "Polyglutamine tract".
- Polyglutamine_tract wikiPageWikiLinkText "poly-glutamine repeats".
- Polyglutamine_tract wikiPageWikiLinkText "polyglutamine (polyQ) tract".
- Polyglutamine_tract wikiPageWikiLinkText "polyglutamine regions".
- Polyglutamine_tract wikiPageWikiLinkText "polyglutamine sequence".
- Polyglutamine_tract wikiPageWikiLinkText "polyglutamine tract".
- Polyglutamine_tract wikiPageWikiLinkText "polyglutamine".
- Polyglutamine_tract wikiPageUsesTemplate Template:Reflist.
- Polyglutamine_tract subject Category:Peptides.
- Polyglutamine_tract hypernym Portion.
- Polyglutamine_tract type AnatomicalStructure.
- Polyglutamine_tract type Biomolecule.
- Polyglutamine_tract type Biomolecule.
- Polyglutamine_tract type Peptide.
- Polyglutamine_tract comment "A polyglutamine tract or polyQ tract is a portion of a protein consisting of a sequence of several glutamine units. A tract typically consists of about 10 to a few hundred such units. A multitude of genes, in various eukaryotic species (including humans), contain a number of repetitions of the nucleotide triplet CAG or CAA. When the gene is translated into a protein, each of these triplets gives rise to a glutamine unit, resulting in a polyglutamine tract.".
- Polyglutamine_tract label "Polyglutamine tract".
- Polyglutamine_tract sameAs Q7226416.
- Polyglutamine_tract sameAs m.05b026z.
- Polyglutamine_tract sameAs Q7226416.
- Polyglutamine_tract wasDerivedFrom Polyglutamine_tract?oldid=696383191.
- Polyglutamine_tract isPrimaryTopicOf Polyglutamine_tract.