Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Piromelatine> ?p ?o }
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- Piromelatine abstract "Piromelatine (Neu-P11) is a multimodal sleep drug under development by Neurim Pharmaceuticals. It is an agonist at melatonin MT1/MT2 and serotonin 5-HT1A/5-HT1D receptors. Nuerim is doing a phase II randomized, placebo controlled trial of cognitive and sleep effects in Alzheimer's disease.Results of a phase II trial on insomnia in 120 adults were announced in 2013, finding piromelatine 20/50 mg improved sleep over 4 weeks vs placebo. Phase 1A/1B studies in 2011, showed safe dose-dependent improvement in sleep. Pre-clinical studies showed antinociceptive antihypertensive and cognitive benefits in rat disease models of pain, hypertension, and Alzheimer's disease.".
- Piromelatine thumbnail Piromelatine.svg?width=300.
- Piromelatine wikiPageID "44203774".
- Piromelatine wikiPageLength "4692".
- Piromelatine wikiPageOutDegree "22".
- Piromelatine wikiPageRevisionID "707012151".
- Piromelatine wikiPageWikiLink 5-HT1A_receptor.
- Piromelatine wikiPageWikiLink 5-HT1D_receptor.
- Piromelatine wikiPageWikiLink Agomelatine.
- Piromelatine wikiPageWikiLink Agonist.
- Piromelatine wikiPageWikiLink Alzheimers_disease.
- Piromelatine wikiPageWikiLink Category:4-Pyrones.
- Piromelatine wikiPageWikiLink Category:5-HT1A_agonists.
- Piromelatine wikiPageWikiLink Category:5-HT1D_agonists.
- Piromelatine wikiPageWikiLink Category:Hypnotics.
- Piromelatine wikiPageWikiLink Category:Indoles.
- Piromelatine wikiPageWikiLink Category:Melatonin_receptor_agonists.
- Piromelatine wikiPageWikiLink Hypnotic.
- Piromelatine wikiPageWikiLink Insomnia.
- Piromelatine wikiPageWikiLink Melatonin.
- Piromelatine wikiPageWikiLink Melatonin_receptor_1A.
- Piromelatine wikiPageWikiLink Melatonin_receptor_1B.
- Piromelatine wikiPageWikiLink Neurim_Pharmaceuticals.
- Piromelatine wikiPageWikiLink Phases_of_clinical_research.
- Piromelatine wikiPageWikiLink Ramelteon.
- Piromelatine wikiPageWikiLink Serotonin.
- Piromelatine wikiPageWikiLink Tasimelteon.
- Piromelatine wikiPageWikiLinkText "Piromelatine".
- Piromelatine c "17".
- Piromelatine casNumber "946846".
- Piromelatine chemspiderid "32700981".
- Piromelatine h "16".
- Piromelatine inchi "1".
- Piromelatine inchikey "PNTNBIHOAPJYDB-UHFFFAOYAD".
- Piromelatine iupacName "N-[2-ethyl]-4-oxopyran-2-carboxamide".
- Piromelatine molecularWeight "312.32".
- Piromelatine n "2".
- Piromelatine o "4".
- Piromelatine pubchem "24815904".
- Piromelatine smiles "COC1=CC2=CNC=C2CCNCC3=CCC=CO3".
- Piromelatine stdinchi "1".
- Piromelatine stdinchikey "PNTNBIHOAPJYDB-UHFFFAOYSA-N".
- Piromelatine wikiPageUsesTemplate Template:Infobox_drug.
- Piromelatine wikiPageUsesTemplate Template:Melatonergics.
- Piromelatine wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Piromelatine wikiPageUsesTemplate Template:Reflist.
- Piromelatine wikiPageUsesTemplate Template:Serotonergics.
- Piromelatine subject Category:4-Pyrones.
- Piromelatine subject Category:5-HT1A_agonists.
- Piromelatine subject Category:5-HT1D_agonists.
- Piromelatine subject Category:Hypnotics.
- Piromelatine subject Category:Indoles.
- Piromelatine subject Category:Melatonin_receptor_agonists.
- Piromelatine hypernym Drug.
- Piromelatine type ChemicalSubstance.
- Piromelatine type Drug.
- Piromelatine type ChemicalObject.
- Piromelatine type Thing.
- Piromelatine type Q8386.
- Piromelatine comment "Piromelatine (Neu-P11) is a multimodal sleep drug under development by Neurim Pharmaceuticals. It is an agonist at melatonin MT1/MT2 and serotonin 5-HT1A/5-HT1D receptors. Nuerim is doing a phase II randomized, placebo controlled trial of cognitive and sleep effects in Alzheimer's disease.Results of a phase II trial on insomnia in 120 adults were announced in 2013, finding piromelatine 20/50 mg improved sleep over 4 weeks vs placebo.".
- Piromelatine label "Piromelatine".
- Piromelatine sameAs Q18388725.
- Piromelatine sameAs m.0125ykwh.
- Piromelatine sameAs Q18388725.
- Piromelatine wasDerivedFrom Piromelatine?oldid=707012151.
- Piromelatine depiction Piromelatine.svg.
- Piromelatine isPrimaryTopicOf Piromelatine.