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- Phylogenetic_footprinting abstract "Phylogenetic footprinting is a technique used to identify transcription factor binding sites (TFBS) within a non-coding region of DNA of interest by comparing it to the orthologous sequence in different species. When this technique is used with a large number of closely related species, this is called phylogenetic shadowing.Researchers have found that non-coding pieces of DNA contain binding sites for regulatory proteins that govern the spatiotemporal expression of genes. These transcription factor binding sites (TFBS), or regulatory motifs, have proven hard to identify, primarily because they are short in length, and can show sequence variation. The importance of understanding transcriptional regulation to many fields of biology has led researchers to develop strategies for predicting the presence of TFBS, many of which have led to publicly available databases. One such technique is Phylogenetic Footprinting.Phylogenetic footprinting relies upon two major concepts: The function and DNA binding preferences of transcription factors are well-conserved between diverse species. Important non-coding DNA sequences that are essential for regulating gene expression will show differential selective pressure. A slower rate of change occurs in TFBS than in other, less critical, parts of the non-coding genome.↑ ↑".
- Phylogenetic_footprinting thumbnail Example_of_the_obtained_Phylogenetic_Footprinting_result_looking_for_upstream_500bp_of_HOXA5_gene.PNG?width=300.
- Phylogenetic_footprinting wikiPageID "9676678".
- Phylogenetic_footprinting wikiPageLength "6956".
- Phylogenetic_footprinting wikiPageOutDegree "21".
- Phylogenetic_footprinting wikiPageRevisionID "590644355".
- Phylogenetic_footprinting wikiPageWikiLink Biology.
- Phylogenetic_footprinting wikiPageWikiLink Category:Phylogenetics.
- Phylogenetic_footprinting wikiPageWikiLink DNA.
- Phylogenetic_footprinting wikiPageWikiLink Deoxyribonuclease.
- Phylogenetic_footprinting wikiPageWikiLink Evolution.
- Phylogenetic_footprinting wikiPageWikiLink File:Example_of_the_obtained_Phylogenetic_Footprinting_result_looking_for_upstream_500bp_of_HOXA5_gene.PNG.
- Phylogenetic_footprinting wikiPageWikiLink File:Phylogenetic_Footprinting_technique_protocol.JPG.
- Phylogenetic_footprinting wikiPageWikiLink Footprinting.
- Phylogenetic_footprinting wikiPageWikiLink Gene.
- Phylogenetic_footprinting wikiPageWikiLink Globulin.
- Phylogenetic_footprinting wikiPageWikiLink Homology_(biology).
- Phylogenetic_footprinting wikiPageWikiLink Molecular_binding.
- Phylogenetic_footprinting wikiPageWikiLink Noncoding_DNA.
- Phylogenetic_footprinting wikiPageWikiLink Phylogenetics.
- Phylogenetic_footprinting wikiPageWikiLink Sequence.
- Phylogenetic_footprinting wikiPageWikiLink Species.
- Phylogenetic_footprinting wikiPageWikiLink Transcription_factor.
- Phylogenetic_footprinting wikiPageWikiLinkText "Phylogenetic footprinting".
- Phylogenetic_footprinting wikiPageWikiLinkText "phylogenetic footprinting".
- Phylogenetic_footprinting subject Category:Phylogenetics.
- Phylogenetic_footprinting hypernym Technique.
- Phylogenetic_footprinting type TopicalConcept.
- Phylogenetic_footprinting type Subfield.
- Phylogenetic_footprinting comment "Phylogenetic footprinting is a technique used to identify transcription factor binding sites (TFBS) within a non-coding region of DNA of interest by comparing it to the orthologous sequence in different species. When this technique is used with a large number of closely related species, this is called phylogenetic shadowing.Researchers have found that non-coding pieces of DNA contain binding sites for regulatory proteins that govern the spatiotemporal expression of genes.".
- Phylogenetic_footprinting label "Phylogenetic footprinting".
- Phylogenetic_footprinting sameAs Q7189437.
- Phylogenetic_footprinting sameAs Þróunarfræðileg_sporun.
- Phylogenetic_footprinting sameAs m.02pnvy2.
- Phylogenetic_footprinting sameAs Q7189437.
- Phylogenetic_footprinting wasDerivedFrom Phylogenetic_footprinting?oldid=590644355.
- Phylogenetic_footprinting depiction Example_of_the_obtained_Phylogenetic_Footprinting_result_looking_for_upstream_500bp_of_HOXA5_gene.PNG.
- Phylogenetic_footprinting isPrimaryTopicOf Phylogenetic_footprinting.