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- topiramate abstract "The combination of the drugs phentermine and topiramate extended-release (ER) (trade name Qsymia kyoo-sim-EE-uh) is a medication used for weight loss. In clinical trials, phentermine/topiramate ER was associated with modest but statistically significant weight loss when compared with placebo. This weight loss was associated with improvements in weight-related comorbidities such as improved glycemia, decreased blood pressure, and improved cholesterol.Phentermine/topiramate ER was developed by Vivus, Inc., a California pharmaceutical company. Phentermine is a sympathomimetic amine which acts as an appetite suppressant and stimulant. Topiramate is an anticonvulsant that has weight loss side effects. The exact mechanism of action for both drugs is unknown.In 2012 the U.S. Food and Drug Administration approved phentermine/topiramate ER as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of at least 30 kg/m², or at least 27 kg/m² (overweight) in the presence of at least one weight-related comorbidity such as hypertension, type 2 diabetes mellitus, or dyslipidemia. Phentermine/topiramate ER is available in certified retail pharmacies nationwide and also available through a certified mail-order pharmacy network. Approval was denied by European regulatory authorities, who cited potential risk to the heart and blood vessels, psychiatric side effects, and cognitive side effects in explaining their decision.".
- topiramate atcPrefix "none".
- topiramate pubchem "56842108".
- topiramate thumbnail Phentermine_and_topiramate.svg?width=300.
- topiramate wikiPageID "25720535".
- topiramate wikiPageLength "9016".
- topiramate wikiPageOutDegree "26".
- topiramate wikiPageRevisionID "702106343".
- topiramate wikiPageWikiLink Amphetamine.
- topiramate wikiPageWikiLink Anorectic.
- topiramate wikiPageWikiLink Anticonvulsant.
- topiramate wikiPageWikiLink Body_mass_index.
- topiramate wikiPageWikiLink Category:Anorectics.
- topiramate wikiPageWikiLink Category:Antiobesity_drugs.
- topiramate wikiPageWikiLink Category:Combination_drugs.
- topiramate wikiPageWikiLink Constipation.
- topiramate wikiPageWikiLink Dysgeusia.
- topiramate wikiPageWikiLink Food_and_Drug_Administration.
- topiramate wikiPageWikiLink Insomnia.
- topiramate wikiPageWikiLink New_drug_application.
- topiramate wikiPageWikiLink Pharmaceutical_drug.
- topiramate wikiPageWikiLink Phenethylamine.
- topiramate wikiPageWikiLink Phentermine.
- topiramate wikiPageWikiLink Placebo.
- topiramate wikiPageWikiLink Stimulant.
- topiramate wikiPageWikiLink Sympathomimetic_drug.
- topiramate wikiPageWikiLink Topiramate.
- topiramate wikiPageWikiLink Vivus.
- topiramate wikiPageWikiLink Xerostomia.
- topiramate wikiPageWikiLinkText "Phentermine/topiramate".
- topiramate wikiPageWikiLinkText "Qsymia".
- topiramate wikiPageWikiLinkText "phentermine and topiramate".
- topiramate wikiPageWikiLinkText "phentermine/topiramate".
- topiramate atcPrefix "none".
- topiramate class Anticonvulsant.
- topiramate class "Appetite suppressant/stimulant of the amphetamine and phenethylamine class".
- topiramate component "Phentermine".
- topiramate component "Topiramate".
- topiramate legalStatus "Rx only".
- topiramate legalUs "Schedule IV".
- topiramate pregnancyUs "X".
- topiramate pubchem "56842108".
- topiramate routesOfAdministration "Oral".
- topiramate tradename "Qsymia".
- topiramate type "combo".
- topiramate verifiedrevid "451550560".
- topiramate watchedfields "changed".
- topiramate width "175".
- topiramate wikiPageUsesTemplate Template:Antiobesity_preparations.
- topiramate wikiPageUsesTemplate Template:Drugbankcite.
- topiramate wikiPageUsesTemplate Template:Drugbox.
- topiramate wikiPageUsesTemplate Template:Reflist.
- topiramate wikiPageUsesTemplate Template:Respell.
- topiramate subject Category:Anorectics.
- topiramate subject Category:Antiobesity_drugs.
- topiramate subject Category:Combination_drugs.
- topiramate hypernym Medication.
- topiramate type ChemicalSubstance.
- topiramate type Drug.
- topiramate type Chemical.
- topiramate type Drug.
- topiramate type Redirect.
- topiramate type ChemicalObject.
- topiramate type Thing.
- topiramate type Q8386.
- topiramate comment "The combination of the drugs phentermine and topiramate extended-release (ER) (trade name Qsymia kyoo-sim-EE-uh) is a medication used for weight loss. In clinical trials, phentermine/topiramate ER was associated with modest but statistically significant weight loss when compared with placebo.".
- topiramate label "Phentermine/topiramate".
- topiramate sameAs Q3378713.
- topiramate sameAs توبيراميت).
- topiramate sameAs _topiramate.
- topiramate sameAs topiramato.
- topiramate sameAs m.09v965n.
- topiramate sameAs topiramat.
- topiramate sameAs topiramat.
- topiramate sameAs Q3378713.
- topiramate wasDerivedFrom topiramate?oldid=702106343.
- topiramate depiction Phentermine_and_topiramate.svg.
- topiramate isPrimaryTopicOf topiramate.