Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/PRMT4_pathway> ?p ?o }
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- PRMT4_pathway abstract "Protein arginine N-methyltransferase-4 (PRMT4/CARM1) methylation of arginine residues within proteins plays a critical key role in transcriptional regulation (see the PRMT4 pathway on the left). PRMT4 binds to the classes of transcriptional activators known as p160 and CBP/p300. The modified forms of these proteins are involved in stimulation of gene expression via steroid hormone receptors. Significantly, PRMT4 methylates core histones H3 and H4, which are also targets of the histone acetylase activity of CBP/p300 coactivators. PRMT4 recruitment of chromatin by binding to coactivators increases histone methylation and enhances the accessibility of promoter regions for transcription. Methylation of the transcriptional coactivator CBP by PRMT4 inhibits binding to CREB and thereby partitions the limited cellular pool of CBP for steroid hormone receptor interaction.".
- PRMT4_pathway thumbnail PRMTpathway.jpg?width=300.
- PRMT4_pathway wikiPageID "11007779".
- PRMT4_pathway wikiPageLength "1803".
- PRMT4_pathway wikiPageOutDegree "28".
- PRMT4_pathway wikiPageRevisionID "442954892".
- PRMT4_pathway wikiPageWikiLink Arginine.
- PRMT4_pathway wikiPageWikiLink Category:Gene_expression.
- PRMT4_pathway wikiPageWikiLink Chromatin.
- PRMT4_pathway wikiPageWikiLink DNA_methyltransferase.
- PRMT4_pathway wikiPageWikiLink Diet_and_cancer.
- PRMT4_pathway wikiPageWikiLink File:PRMTpathway.jpg.
- PRMT4_pathway wikiPageWikiLink Gene_expression.
- PRMT4_pathway wikiPageWikiLink Histone.
- PRMT4_pathway wikiPageWikiLink Histone-modifying_enzymes.
- PRMT4_pathway wikiPageWikiLink Hormone_receptor.
- PRMT4_pathway wikiPageWikiLink Methylation.
- PRMT4_pathway wikiPageWikiLink Methyltransferase.
- PRMT4_pathway wikiPageWikiLink Nucleosome.
- PRMT4_pathway wikiPageWikiLink Promoter_(genetics).
- PRMT4_pathway wikiPageWikiLink Protein.
- PRMT4_pathway wikiPageWikiLink Steroid_hormone.
- PRMT4_pathway wikiPageWikiLink Transcription_(genetics).
- PRMT4_pathway wikiPageWikiLinkText "PRMT4 pathway".
- PRMT4_pathway wikiPageUsesTemplate Template:Reflist.
- PRMT4_pathway subject Category:Gene_expression.
- PRMT4_pathway type Process.
- PRMT4_pathway comment "Protein arginine N-methyltransferase-4 (PRMT4/CARM1) methylation of arginine residues within proteins plays a critical key role in transcriptional regulation (see the PRMT4 pathway on the left). PRMT4 binds to the classes of transcriptional activators known as p160 and CBP/p300. The modified forms of these proteins are involved in stimulation of gene expression via steroid hormone receptors.".
- PRMT4_pathway label "PRMT4 pathway".
- PRMT4_pathway sameAs Q7120364.
- PRMT4_pathway sameAs m.02qxytk.
- PRMT4_pathway sameAs Q7120364.
- PRMT4_pathway wasDerivedFrom PRMT4_pathway?oldid=442954892.
- PRMT4_pathway depiction PRMTpathway.jpg.
- PRMT4_pathway isPrimaryTopicOf PRMT4_pathway.