Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/PRKCH> ?p ?o }
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- PRKCH abstract "Protein kinase C eta type is an enzyme that in humans is encoded by the PRKCH gene.Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.".
- PRKCH entrezgene "5583".
- PRKCH wikiPageID "14753872".
- PRKCH wikiPageLength "8624".
- PRKCH wikiPageOutDegree "5".
- PRKCH wikiPageRevisionID "704366803".
- PRKCH wikiPageWikiLink Calcium.
- PRKCH wikiPageWikiLink Category:EC_2.7.11.
- PRKCH wikiPageWikiLink Enzyme.
- PRKCH wikiPageWikiLink Gene.
- PRKCH wikiPageWikiLink Protein.
- PRKCH wikiPageWikiLinkText "PKC-η".
- PRKCH wikiPageWikiLinkText "PRKCH".
- PRKCH requireManualInspection "no".
- PRKCH summaryText "Protein kinase C is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 -activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha . It is also found to mediate the transcription activation of the transglutaminase 1 gene.".
- PRKCH updateCitations "yes".
- PRKCH updatePage "yes".
- PRKCH updateProteinBox "yes".
- PRKCH updateSummary "yes".
- PRKCH wikiPageUsesTemplate Template:Cite_journal.
- PRKCH wikiPageUsesTemplate Template:Enzymes.
- PRKCH wikiPageUsesTemplate Template:Gene-14-stub.
- PRKCH wikiPageUsesTemplate Template:PBB.
- PRKCH wikiPageUsesTemplate Template:PBB_Controls.
- PRKCH wikiPageUsesTemplate Template:PBB_Further_reading.
- PRKCH wikiPageUsesTemplate Template:PBB_Summary.
- PRKCH wikiPageUsesTemplate Template:PDB_Gallery.
- PRKCH wikiPageUsesTemplate Template:Portal_bar.
- PRKCH wikiPageUsesTemplate Template:Refbegin.
- PRKCH wikiPageUsesTemplate Template:Refend.
- PRKCH wikiPageUsesTemplate Template:Reflist.
- PRKCH wikiPageUsesTemplate threonine-specific_protein_kinases.
- PRKCH subject Category:EC_2.7.11.
- PRKCH hypernym Enzyme.
- PRKCH type Biomolecule.
- PRKCH type Protein.
- PRKCH type Thing.
- PRKCH type Q206229.
- PRKCH type Q8054.
- PRKCH comment "Protein kinase C eta type is an enzyme that in humans is encoded by the PRKCH gene.Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters.".
- PRKCH label "PRKCH".
- PRKCH sameAs Q18030775.
- PRKCH sameAs m.03gwpqz.
- PRKCH sameAs Q18030775.
- PRKCH wasDerivedFrom PRKCH?oldid=704366803.
- PRKCH isPrimaryTopicOf PRKCH.