Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/PRKAB1> ?p ?o }
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- PRKAB1 abstract "5'-AMP-activated protein kinase subunit beta-1 is an enzyme that in humans is encoded by the PRKAB1 gene.The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.".
- PRKAB1 entrezgene "5564".
- PRKAB1 symbol "AMPKBI".
- PRKAB1 wikiPageID "14754244".
- PRKAB1 wikiPageLength "16239".
- PRKAB1 wikiPageOutDegree "36".
- PRKAB1 wikiPageRevisionID "699375120".
- PRKAB1 wikiPageWikiLink Antibody.
- PRKAB1 wikiPageWikiLink Auditory_brainstem_response.
- PRKAB1 wikiPageWikiLink Bilirubin.
- PRKAB1 wikiPageWikiLink Blood_plasma.
- PRKAB1 wikiPageWikiLink Category:EC_2.7.11.
- PRKAB1 wikiPageWikiLink Category:Genes_mutated_in_mice.
- PRKAB1 wikiPageWikiLink Citrobacter.
- PRKAB1 wikiPageWikiLink Clinical_chemistry.
- PRKAB1 wikiPageWikiLink Dominance_(genetics).
- PRKAB1 wikiPageWikiLink Dual-energy_X-ray_absorptiometry.
- PRKAB1 wikiPageWikiLink Enzyme.
- PRKAB1 wikiPageWikiLink Gene.
- PRKAB1 wikiPageWikiLink Glucose_tolerance_test.
- PRKAB1 wikiPageWikiLink Hematology.
- PRKAB1 wikiPageWikiLink Homology_(biology).
- PRKAB1 wikiPageWikiLink Hot_plate_test.
- PRKAB1 wikiPageWikiLink Impaired_glucose_tolerance.
- PRKAB1 wikiPageWikiLink Indirect_calorimetry.
- PRKAB1 wikiPageWikiLink International_Knockout_Mouse_Consortium.
- PRKAB1 wikiPageWikiLink Knockout_mouse.
- PRKAB1 wikiPageWikiLink Micronucleus_test.
- PRKAB1 wikiPageWikiLink Model_organism.
- PRKAB1 wikiPageWikiLink Multiprotein_complex.
- PRKAB1 wikiPageWikiLink Mutant.
- PRKAB1 wikiPageWikiLink Open_Field_(animal_test).
- PRKAB1 wikiPageWikiLink PRKAG1.
- PRKAB1 wikiPageWikiLink PRKAG2.
- PRKAB1 wikiPageWikiLink Peripheral_blood_lymphocyte.
- PRKAB1 wikiPageWikiLink Phenotypic_screening.
- PRKAB1 wikiPageWikiLink Protein–protein_interaction.
- PRKAB1 wikiPageWikiLink Radiography.
- PRKAB1 wikiPageWikiLink Saccharomyces_cerevisiae.
- PRKAB1 wikiPageWikiLink Salmonella.
- PRKAB1 wikiPageWikiLink Teratology.
- PRKAB1 wikiPageWikiLink Zygosity.
- PRKAB1 wikiPageWikiLinkText "PRKAB1".
- PRKAB1 caption "crystal structure of the adenylate sensor from amp-activated protein kinase complexed with atp".
- PRKAB1 interpro "IPR006828".
- PRKAB1 name "AMPKBI".
- PRKAB1 pfam "PF04739".
- PRKAB1 requireManualInspection "no".
- PRKAB1 summaryText "The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase and beta-hydroxy beta-methylglutaryl-CoA reductase , key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.".
- PRKAB1 symbol "AMPKBI".
- PRKAB1 updateCitations "yes".
- PRKAB1 updatePage "yes".
- PRKAB1 updateProteinBox "yes".
- PRKAB1 updateSummary "yes".
- PRKAB1 wikiPageUsesTemplate Template:Cite_journal.
- PRKAB1 wikiPageUsesTemplate Template:Enzymes.
- PRKAB1 wikiPageUsesTemplate Template:Infobox_protein_family.
- PRKAB1 wikiPageUsesTemplate Template:InterPro_content.
- PRKAB1 wikiPageUsesTemplate Template:PBB.
- PRKAB1 wikiPageUsesTemplate Template:PBB_Controls.
- PRKAB1 wikiPageUsesTemplate Template:PBB_Further_reading.
- PRKAB1 wikiPageUsesTemplate Template:PBB_Summary.
- PRKAB1 wikiPageUsesTemplate Template:PDB_Gallery.
- PRKAB1 wikiPageUsesTemplate Template:Portal_bar.
- PRKAB1 wikiPageUsesTemplate Template:Refbegin.
- PRKAB1 wikiPageUsesTemplate Template:Refend.
- PRKAB1 wikiPageUsesTemplate Template:Reflist.
- PRKAB1 wikiPageUsesTemplate threonine-specific_protein_kinases.
- PRKAB1 subject Category:EC_2.7.11.
- PRKAB1 subject Category:Genes_mutated_in_mice.
- PRKAB1 hypernym Enzyme.
- PRKAB1 type Biomolecule.
- PRKAB1 type Protein.
- PRKAB1 type Redirect.
- PRKAB1 type Thing.
- PRKAB1 type Q206229.
- PRKAB1 type Q8054.
- PRKAB1 comment "5'-AMP-activated protein kinase subunit beta-1 is an enzyme that in humans is encoded by the PRKAB1 gene.The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status.".
- PRKAB1 label "PRKAB1".
- PRKAB1 sameAs Q18030758.
- PRKAB1 sameAs m.03gwqm5.
- PRKAB1 sameAs Q18030758.
- PRKAB1 wasDerivedFrom PRKAB1?oldid=699375120.
- PRKAB1 isPrimaryTopicOf PRKAB1.