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- PCDHY abstract "PCDH11Y is a gene unique to human males which competes with FOXP2 for the title of the \"language gene.\" PCDH11Y is the gene for making Protocadherin 11Y, a protein that guides the development of nerve cells. PCDH11X, located on the X chromosome, is common, in both sexes, to humans and our nearest relative, the chimpanzee; however, PCDH11Y, located on the Y chromosome, is unique to men.In terms of human evolution, it has been estimated that pcdh11x \"gene jumped\" from X to Y around three million years ago; coincident with increased human brain size and the first use of tools. Furthermore, around 120,000 to 200,000 years ago, the PCDH11Y gene was able to further transform, splitting in half and reversing its position.PCDH11X/Y are cadherin family genes. They make proteins, involved in signalling, that attach to the surface of nerve cells. PCDH11X and PCDH11Y, respond in different ways to Retinoic acid, a chemical involved in the development of embryos. The acid stimulates the activity of PCDH11Y but suppresses PCDH11X. This is likely one of the explanations for the differences between the brains of men and women.Psychiatrist, professor Tim Crow, also believes the gene explains lateralisation. Humans have \"lateralised\" brains, in which the different sides became specialised for particular jobs. For instance 90% of people will use their right hands for fiddly tasks. A chimpanzee is just as likely to use either hand. It also explains why, for right-handed people, linguistic functions are concentrated on the left side of the brain.".
- PCDHY wikiPageID "24889736".
- PCDHY wikiPageLength "2178".
- PCDHY wikiPageOutDegree "20".
- PCDHY wikiPageRevisionID "670740801".
- PCDHY wikiPageWikiLink Brain_size.
- PCDHY wikiPageWikiLink Cadherin.
- PCDHY wikiPageWikiLink Category:Genes_on_human_chromosome_Y.
- PCDHY wikiPageWikiLink Chimpanzee.
- PCDHY wikiPageWikiLink Embryo.
- PCDHY wikiPageWikiLink FOXP2.
- PCDHY wikiPageWikiLink Gene.
- PCDHY wikiPageWikiLink Handedness.
- PCDHY wikiPageWikiLink Lateralization_of_brain_function.
- PCDHY wikiPageWikiLink Neuron.
- PCDHY wikiPageWikiLink PCDH11X.
- PCDHY wikiPageWikiLink Protein.
- PCDHY wikiPageWikiLink Protocadherin.
- PCDHY wikiPageWikiLink Psychiatrist.
- PCDHY wikiPageWikiLink Retinoic_acid.
- PCDHY wikiPageWikiLink Tim_Crow.
- PCDHY wikiPageWikiLink Transmembrane_protein.
- PCDHY wikiPageWikiLink Transposable_element.
- PCDHY wikiPageWikiLink X_chromosome.
- PCDHY wikiPageWikiLink Y_chromosome.
- PCDHY wikiPageWikiLinkText "PCDH11Y".
- PCDHY wikiPageWikiLinkText "PCDHY".
- PCDHY wikiPageUsesTemplate Template:Gene-stub.
- PCDHY wikiPageUsesTemplate Template:Reflist.
- PCDHY subject Category:Genes_on_human_chromosome_Y.
- PCDHY hypernym Gene.
- PCDHY type Protein.
- PCDHY comment "PCDH11Y is a gene unique to human males which competes with FOXP2 for the title of the \"language gene.\" PCDH11Y is the gene for making Protocadherin 11Y, a protein that guides the development of nerve cells.".
- PCDHY label "PCDHY".
- PCDHY sameAs Q7118567.
- PCDHY sameAs m.09gbbb1.
- PCDHY sameAs Q7118567.
- PCDHY wasDerivedFrom PCDHY?oldid=670740801.
- PCDHY isPrimaryTopicOf PCDHY.