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- PCDHA12 abstract "Protocadherin alpha-12 is a protein that in humans is encoded by the PCDHA12 gene.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.".
- PCDHA12 entrezgene "56137".
- PCDHA12 wikiPageID "15220926".
- PCDHA12 wikiPageLength "6260".
- PCDHA12 wikiPageOutDegree "8".
- PCDHA12 wikiPageRevisionID "685030483".
- PCDHA12 wikiPageWikiLink B_cell.
- PCDHA12 wikiPageWikiLink Cadherin.
- PCDHA12 wikiPageWikiLink Chromosome.
- PCDHA12 wikiPageWikiLink Exon.
- PCDHA12 wikiPageWikiLink Gene.
- PCDHA12 wikiPageWikiLink Protein.
- PCDHA12 wikiPageWikiLink T_cell.
- PCDHA12 wikiPageWikiLinkText "PCDHA12".
- PCDHA12 requireManualInspection "no".
- PCDHA12 summaryText "This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.".
- PCDHA12 updateCitations "yes".
- PCDHA12 updatePage "yes".
- PCDHA12 updateProteinBox "yes".
- PCDHA12 updateSummary "yes".
- PCDHA12 wikiPageUsesTemplate Template:Cite_journal.
- PCDHA12 wikiPageUsesTemplate Template:PBB.
- PCDHA12 wikiPageUsesTemplate Template:PBB_Controls.
- PCDHA12 wikiPageUsesTemplate Template:PBB_Further_reading.
- PCDHA12 wikiPageUsesTemplate Template:PBB_Summary.
- PCDHA12 wikiPageUsesTemplate Template:Protein-stub.
- PCDHA12 wikiPageUsesTemplate Template:Refbegin.
- PCDHA12 wikiPageUsesTemplate Template:Refend.
- PCDHA12 wikiPageUsesTemplate Template:Reflist.
- PCDHA12 hypernym Protein.
- PCDHA12 type Biomolecule.
- PCDHA12 type Protein.
- PCDHA12 type Thing.
- PCDHA12 type Q206229.
- PCDHA12 type Q8054.
- PCDHA12 comment "Protocadherin alpha-12 is a protein that in humans is encoded by the PCDHA12 gene.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.".
- PCDHA12 label "PCDHA12".
- PCDHA12 sameAs Q18042284.
- PCDHA12 sameAs m.03hmbhj.
- PCDHA12 sameAs Q18042284.
- PCDHA12 wasDerivedFrom PCDHA12?oldid=685030483.
- PCDHA12 isPrimaryTopicOf PCDHA12.