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- P7C3 abstract "P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and similar neurodegenerative disorders. The precise mechanism of action through which these effects are exerted remains unclear as of 2010, but the pharmacological effects of P7C3 in vitro resemble those of endogenous proneurogenic peptides such as fibroblast growth factor 1, and the proneurogenic activity of P7C3 was around thirty times that of dimebon when they were compared side by side in mice. P7C3 was chosen for further animal studies on the basis of favourable pharmacokinetic factors, such as its high oral bioavailability and long duration of action, but several other related compounds showed similar activity such as the more potent fluorinated analogue P7C3A20 which is up to ten times stronger again, and the methoxy analogue P7C3-OMe, for which it was determined that the (R) enantiomer is the active form.".
- P7C3 iupacName "1-anilino-3-(3,6-dibromocarbazol-9-yl)propan-2-ol".
- P7C3 pubchem "2836187".
- P7C3 thumbnail P7C3_structure.png?width=300.
- P7C3 wikiPageID "28020089".
- P7C3 wikiPageLength "3424".
- P7C3 wikiPageOutDegree "13".
- P7C3 wikiPageRevisionID "666400744".
- P7C3 wikiPageWikiLink Alzheimers_disease.
- P7C3 wikiPageWikiLink Bioavailability.
- P7C3 wikiPageWikiLink Category:Alcohols.
- P7C3 wikiPageWikiLink Category:Bromoarenes.
- P7C3 wikiPageWikiLink Category:Carbazoles.
- P7C3 wikiPageWikiLink Category:Nootropics.
- P7C3 wikiPageWikiLink Enantiomer.
- P7C3 wikiPageWikiLink FGF1.
- P7C3 wikiPageWikiLink Latrepirdine.
- P7C3 wikiPageWikiLink Neurogenesis.
- P7C3 wikiPageWikiLink Neuroprotection.
- P7C3 wikiPageWikiLink Pharmacokinetics.
- P7C3 wikiPageWikiLink File:P7C3_derivatives.png.
- P7C3 wikiPageWikiLinkText "P7C3".
- P7C3 br "2".
- P7C3 c "21".
- P7C3 chembl "2442630".
- P7C3 chemspiderid "2113543".
- P7C3 h "18".
- P7C3 inchi "1".
- P7C3 inchikey "FZHHRERIIVOATI-UHFFFAOYAJ".
- P7C3 iupacName "1".
- P7C3 molecularWeight "474.188".
- P7C3 n "2".
- P7C3 o "1".
- P7C3 pubchem "2836187".
- P7C3 smiles "c4ccccc4NCCCn2c1ccccc1cc2ccc3Br".
- P7C3 stdinchi "1".
- P7C3 stdinchikey "FZHHRERIIVOATI-UHFFFAOYSA-N".
- P7C3 verifiedfields "changed".
- P7C3 verifiedrevid "451562732".
- P7C3 width "240".
- P7C3 wikiPageUsesTemplate Template:Chemspidercite.
- P7C3 wikiPageUsesTemplate Template:Clear-left.
- P7C3 wikiPageUsesTemplate Template:Drugbankcite.
- P7C3 wikiPageUsesTemplate Template:Drugbox.
- P7C3 wikiPageUsesTemplate Template:Ebicite.
- P7C3 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- P7C3 wikiPageUsesTemplate Template:Nootropics.
- P7C3 wikiPageUsesTemplate Template:Reflist.
- P7C3 wikiPageUsesTemplate Template:Stdinchicite.
- P7C3 wikiPageUsesTemplate Template:Tricyclics.
- P7C3 subject Category:Alcohols.
- P7C3 subject Category:Bromoarenes.
- P7C3 subject Category:Carbazoles.
- P7C3 subject Category:Nootropics.
- P7C3 hypernym Drug.
- P7C3 type ChemicalSubstance.
- P7C3 type Drug.
- P7C3 type Alcohol.
- P7C3 type Chemical.
- P7C3 type Drug.
- P7C3 type Heterocycle.
- P7C3 type Nootropic.
- P7C3 type Organohalide.
- P7C3 type Psychoanaleptic.
- P7C3 type Organohalide.
- P7C3 type ChemicalObject.
- P7C3 type Thing.
- P7C3 type Q8386.
- P7C3 comment "P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and similar neurodegenerative disorders.".
- P7C3 label "P7C3".
- P7C3 sameAs Q7117948.
- P7C3 sameAs m.0ch5nb3.
- P7C3 sameAs P7C3.
- P7C3 sameAs P7C3.
- P7C3 sameAs P7C3.
- P7C3 sameAs Q7117948.
- P7C3 wasDerivedFrom P7C3?oldid=666400744.
- P7C3 depiction P7C3_structure.png.
- P7C3 isPrimaryTopicOf P7C3.