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- P70S6_kinase abstract "p70S6 kinase or p70S6K is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. As the name suggests, its target substrate is the S6 ribosomal protein. Phosphorylation of S6 induces protein synthesis at the ribosome.The phosphorylation of P70S6K at threonine 389 has been used as a hallmark of activation by mTOR and correlated with autophagy inhibition in various situations. However, several recent studies suggest that the activity of P70S6K plays a more positive role in the increase of autophagy.".
- P70S6_kinase wikiPageID "4410801".
- P70S6_kinase wikiPageLength "3493".
- P70S6_kinase wikiPageOutDegree "23".
- P70S6_kinase wikiPageRevisionID "699090627".
- P70S6_kinase wikiPageWikiLink Amino_acid.
- P70S6_kinase wikiPageWikiLink Category:EC_2.7.11.
- P70S6_kinase wikiPageWikiLink Category:Protein_kinases.
- P70S6_kinase wikiPageWikiLink Growth_factor.
- P70S6_kinase wikiPageWikiLink Insulin-like_growth_factor_1.
- P70S6_kinase wikiPageWikiLink Kinase.
- P70S6_kinase wikiPageWikiLink Leucine.
- P70S6_kinase wikiPageWikiLink Mechanistic_target_of_rapamycin.
- P70S6_kinase wikiPageWikiLink Muscle.
- P70S6_kinase wikiPageWikiLink Phosphatidylinositol_(3,4,5)-trisphosphate.
- P70S6_kinase wikiPageWikiLink Phosphoinositide-dependent_kinase-1.
- P70S6_kinase wikiPageWikiLink Phosphoinositide_3-kinase.
- P70S6_kinase wikiPageWikiLink Phosphorylation.
- P70S6_kinase wikiPageWikiLink Physical_exercise.
- P70S6_kinase wikiPageWikiLink Protein.
- P70S6_kinase wikiPageWikiLink Protein_kinase_B.
- P70S6_kinase wikiPageWikiLink Ribosomal_protein.
- P70S6_kinase wikiPageWikiLink Ribosomal_protein_s6.
- P70S6_kinase wikiPageWikiLink threonine-specific_protein_kinase.
- P70S6_kinase wikiPageWikiLink Signal_transduction.
- P70S6_kinase wikiPageWikiLink Sirolimus.
- P70S6_kinase wikiPageWikiLink Substrate_(chemistry).
- P70S6_kinase wikiPageWikiLinkText "P70S6 kinase".
- P70S6_kinase wikiPageWikiLinkText "P70S6_kinase".
- P70S6_kinase wikiPageWikiLinkText "p70S6k".
- P70S6_kinase wikiPageUsesTemplate Template:Enzymes.
- P70S6_kinase wikiPageUsesTemplate Template:Merge_to.
- P70S6_kinase wikiPageUsesTemplate Template:Portal_bar.
- P70S6_kinase wikiPageUsesTemplate Template:Reflist.
- P70S6_kinase wikiPageUsesTemplate threonine-specific_protein_kinases.
- P70S6_kinase subject Category:EC_2.7.11.
- P70S6_kinase subject Category:Protein_kinases.
- P70S6_kinase hypernym Kinase.
- P70S6_kinase type Protein.
- P70S6_kinase type Redirect.
- P70S6_kinase comment "p70S6 kinase or p70S6K is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. As the name suggests, its target substrate is the S6 ribosomal protein. Phosphorylation of S6 induces protein synthesis at the ribosome.The phosphorylation of P70S6K at threonine 389 has been used as a hallmark of activation by mTOR and correlated with autophagy inhibition in various situations.".
- P70S6_kinase label "P70S6 kinase".
- P70S6_kinase sameAs Q7117944.
- P70S6_kinase sameAs m.0c0t1v.
- P70S6_kinase sameAs Q7117944.
- P70S6_kinase wasDerivedFrom P70S6_kinase?oldid=699090627.
- P70S6_kinase isPrimaryTopicOf P70S6_kinase.