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- Oxidopamine abstract "Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain. 6-OHDA is thought to enter the neurons via the dopamine and noradrenaline (norepinephrine) reuptake transporters. Oxidopamine is often used in conjunction with a selective noradrenaline reuptake inhibitor (such as desipramine) to selectively destroy dopaminergic neurons.The main use for oxidopamine in scientific research is to induce Parkinsonism in laboratory animals such as mice, rats and monkeys, in order to develop and test new medicines and treatments for Parkinson's disease. In order to induce this condition in animals, around 70% of the dopaminergic neurons in the substantia nigra of the brain must be destroyed, and this is achieved either with oxidopamine or MPTP. Both these agents likely destroy neurons by generating reactive oxygen species such as superoxide radical. Oxidopamine toxicity in neonatal rodents is also used as an animal model for the Lesch-Nyhan syndrome.".
- Oxidopamine iupacName "5-(2-Aminoethyl)benzene-1,2,4-triol".
- Oxidopamine thumbnail 6-Hydroxydopamine.svg?width=300.
- Oxidopamine wikiPageID "18373244".
- Oxidopamine wikiPageLength "3121".
- Oxidopamine wikiPageOutDegree "21".
- Oxidopamine wikiPageRevisionID "646462502".
- Oxidopamine wikiPageWikiLink 5,7-Dihydroxytryptamine.
- Oxidopamine wikiPageWikiLink Category:Catecholamines.
- Oxidopamine wikiPageWikiLink Category:Neurotoxins.
- Oxidopamine wikiPageWikiLink DSP-4.
- Oxidopamine wikiPageWikiLink Desipramine.
- Oxidopamine wikiPageWikiLink Dopamine.
- Oxidopamine wikiPageWikiLink Dopaminergic.
- Oxidopamine wikiPageWikiLink Lesch–Nyhan_syndrome.
- Oxidopamine wikiPageWikiLink MPTP.
- Oxidopamine wikiPageWikiLink Monoamine_transporter.
- Oxidopamine wikiPageWikiLink Neurotoxin.
- Oxidopamine wikiPageWikiLink Norepinephrine.
- Oxidopamine wikiPageWikiLink Norsalsolinol.
- Oxidopamine wikiPageWikiLink Organic_compound.
- Oxidopamine wikiPageWikiLink Parkinsonism.
- Oxidopamine wikiPageWikiLink Parkinsons_disease.
- Oxidopamine wikiPageWikiLink Rotenone.
- Oxidopamine wikiPageWikiLink Substantia_nigra.
- Oxidopamine wikiPageWikiLink Superoxide.
- Oxidopamine wikiPageWikiLinkText "6-OHDA".
- Oxidopamine wikiPageWikiLinkText "6-hydroxydopamine model".
- Oxidopamine wikiPageWikiLinkText "Oxidopamine".
- Oxidopamine wikiPageWikiLinkText "oxidopamine".
- Oxidopamine imagefile "6".
- Oxidopamine imagefile "Oxidopamine-3D-balls.png".
- Oxidopamine imagesize "200".
- Oxidopamine iupacname "5".
- Oxidopamine verifiedfields "changed".
- Oxidopamine verifiedrevid "408784062".
- Oxidopamine wikiPageUsesTemplate Template:Adrenergics.
- Oxidopamine wikiPageUsesTemplate Template:Cascite.
- Oxidopamine wikiPageUsesTemplate Template:Chembox.
- Oxidopamine wikiPageUsesTemplate Template:Chembox_Hazards.
- Oxidopamine wikiPageUsesTemplate Template:Chembox_Identifiers.
- Oxidopamine wikiPageUsesTemplate Template:Chembox_Properties.
- Oxidopamine wikiPageUsesTemplate Template:Chemspidercite.
- Oxidopamine wikiPageUsesTemplate Template:Dopaminergics.
- Oxidopamine wikiPageUsesTemplate Template:Ebicite.
- Oxidopamine wikiPageUsesTemplate Template:Fdacite.
- Oxidopamine wikiPageUsesTemplate Template:Keggcite.
- Oxidopamine wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Oxidopamine wikiPageUsesTemplate Template:Neurotoxins.
- Oxidopamine wikiPageUsesTemplate Template:Phenethylamines.
- Oxidopamine wikiPageUsesTemplate Template:Reflist.
- Oxidopamine wikiPageUsesTemplate Template:Stdinchicite.
- Oxidopamine subject Category:Catecholamines.
- Oxidopamine subject Category:Neurotoxins.
- Oxidopamine hypernym Compound.
- Oxidopamine type ChemicalCompound.
- Oxidopamine type ChemicalSubstance.
- Oxidopamine type Drug.
- Oxidopamine type Catechol.
- Oxidopamine type Chemical.
- Oxidopamine type Drug.
- Oxidopamine type Hormone.
- Oxidopamine type Redirect.
- Oxidopamine type ChemicalObject.
- Oxidopamine type Thing.
- Oxidopamine type Q11173.
- Oxidopamine comment "Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain. 6-OHDA is thought to enter the neurons via the dopamine and noradrenaline (norepinephrine) reuptake transporters.".
- Oxidopamine label "Oxidopamine".
- Oxidopamine sameAs Q780181.
- Oxidopamine sameAs Oxidopamina.
- Oxidopamine sameAs ۶-هیدروکسیدوپامین.
- Oxidopamine sameAs 6-Hydroxydopamine.
- Oxidopamine sameAs Oxidopamin.
- Oxidopamine sameAs 6-ヒドロキシドーパミン.
- Oxidopamine sameAs m.04f1qsw.
- Oxidopamine sameAs Oksidopamin.
- Oxidopamine sameAs Oksidopamin.
- Oxidopamine sameAs Q780181.
- Oxidopamine wasDerivedFrom Oxidopamine?oldid=646462502.
- Oxidopamine depiction 6-Hydroxydopamine.svg.
- Oxidopamine isPrimaryTopicOf Oxidopamine.