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- Osmotic_nephrosis abstract "Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to the formation of large vacuoles in the cytoplasm. These vacuoles occur in the presence of large amounts of certain solutes circulating in the tubules. However, despite the condition's name, the solutes do not cause change through osmotic forces but through pinocytosis. Once inside the cytoplasm, pinocytic vacuoles combine with each other and with lysosomes to form large vacuoles that appear transparent under microscopic examination.There may be no symptomatic presentation with this condition, or it may confused with other nephrotic conditions such as Tubular calcineurin-inhibitor toxicity. Affected cells of the proximal tubule may be passed in the urine, but a kidney biopsy is the only sure way to make a diagnosis.Responsible exogenous solutes include sucrose-containing IVIg, mannitol, dextran, contrast dye, and hydroxyethyl starch. Prevention includes standard preventions for iatrogenic kidney damage. Osmotic nephrosis is usually reversible but can lead to chronic renal failure.".
- Osmotic_nephrosis wikiPageExternalLink 5001737f1.html.
- Osmotic_nephrosis wikiPageID "16208645".
- Osmotic_nephrosis wikiPageLength "1750".
- Osmotic_nephrosis wikiPageOutDegree "20".
- Osmotic_nephrosis wikiPageRevisionID "532039607".
- Osmotic_nephrosis wikiPageWikiLink Biopsy.
- Osmotic_nephrosis wikiPageWikiLink Calcineurin.
- Osmotic_nephrosis wikiPageWikiLink Category:Nephrology.
- Osmotic_nephrosis wikiPageWikiLink Cell_(biology).
- Osmotic_nephrosis wikiPageWikiLink Cytoplasm.
- Osmotic_nephrosis wikiPageWikiLink Dextran.
- Osmotic_nephrosis wikiPageWikiLink Hydroxyethyl_starch.
- Osmotic_nephrosis wikiPageWikiLink Iatrogenesis.
- Osmotic_nephrosis wikiPageWikiLink Kidney.
- Osmotic_nephrosis wikiPageWikiLink Lysosome.
- Osmotic_nephrosis wikiPageWikiLink Mannitol.
- Osmotic_nephrosis wikiPageWikiLink Nephrosis.
- Osmotic_nephrosis wikiPageWikiLink Osmosis.
- Osmotic_nephrosis wikiPageWikiLink Pinocytosis.
- Osmotic_nephrosis wikiPageWikiLink Renal_failure.
- Osmotic_nephrosis wikiPageWikiLink Solution.
- Osmotic_nephrosis wikiPageWikiLink Sucrose.
- Osmotic_nephrosis wikiPageWikiLink Tubule.
- Osmotic_nephrosis wikiPageWikiLink Urine.
- Osmotic_nephrosis wikiPageWikiLink Vacuole.
- Osmotic_nephrosis wikiPageWikiLinkText "osmotic nephrosis".
- Osmotic_nephrosis subject Category:Nephrology.
- Osmotic_nephrosis type Specialty.
- Osmotic_nephrosis comment "Osmotic nephrosis refers to structural changes that occur at the cellular level in the human kidney. Cells, primarily of the straight proximal tubule, swell due to the formation of large vacuoles in the cytoplasm. These vacuoles occur in the presence of large amounts of certain solutes circulating in the tubules. However, despite the condition's name, the solutes do not cause change through osmotic forces but through pinocytosis.".
- Osmotic_nephrosis label "Osmotic nephrosis".
- Osmotic_nephrosis sameAs Q7107235.
- Osmotic_nephrosis sameAs m.03wc_0c.
- Osmotic_nephrosis sameAs Q7107235.
- Osmotic_nephrosis wasDerivedFrom Osmotic_nephrosis?oldid=532039607.
- Osmotic_nephrosis isPrimaryTopicOf Osmotic_nephrosis.