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- Organothiophosphate abstract "Organothiophosphates are a subclass of organophosphorus compounds. Many of these compounds are used as pesticides, some have medical applications, and some are used as oil additives. They generally have the chemical formula (RO)3PS, [(RO)2P(S)O]-, R(RO)2PS, etc.Oligonucleotide phosphorothioates (OPS) are modified oligonucleotides where one of the oxygen atoms in the phosphate moiety is replaced by sulfur. These compounds are the basis of antisense therapy, e.g., the drugs fomivirsen (Vitravene), Oblimersen, Alicaforsen, and Mipomersen (Kynamro).Further examples of these include: Diazinon Fenitrothion Fenthion ThioTEPAVariants with P=O double bonds were developed as insecticides because of their reduced mammalian toxicity. The phosphorothioate P=S bond is converted to the toxic P=O bond in the target insect. Similar oxidative conversion in mammals is slower, conferring lower toxicity in mammals.".
- Organothiophosphate thumbnail Echothiophate.svg?width=300.
- Organothiophosphate wikiPageID "5752235".
- Organothiophosphate wikiPageLength "2878".
- Organothiophosphate wikiPageOutDegree "24".
- Organothiophosphate wikiPageRevisionID "698055746".
- Organothiophosphate wikiPageWikiLink Alcohol.
- Organothiophosphate wikiPageWikiLink Alicaforsen.
- Organothiophosphate wikiPageWikiLink Amifostine.
- Organothiophosphate wikiPageWikiLink Antisense_therapy.
- Organothiophosphate wikiPageWikiLink Category:Phosphorothioates.
- Organothiophosphate wikiPageWikiLink Chemotherapy.
- Organothiophosphate wikiPageWikiLink Chlorpyrifos.
- Organothiophosphate wikiPageWikiLink Diazinon.
- Organothiophosphate wikiPageWikiLink Diethyl_dithiophosphoric_acid.
- Organothiophosphate wikiPageWikiLink Dimethyl_dithiophosphoric_acid.
- Organothiophosphate wikiPageWikiLink Echothiophate.
- Organothiophosphate wikiPageWikiLink Fenitrothion.
- Organothiophosphate wikiPageWikiLink Fenthion.
- Organothiophosphate wikiPageWikiLink Fomivirsen.
- Organothiophosphate wikiPageWikiLink Glaucoma.
- Organothiophosphate wikiPageWikiLink Insecticide.
- Organothiophosphate wikiPageWikiLink Malathion.
- Organothiophosphate wikiPageWikiLink Mipomersen.
- Organothiophosphate wikiPageWikiLink Oblimersen.
- Organothiophosphate wikiPageWikiLink Organophosphorus_compound.
- Organothiophosphate wikiPageWikiLink Pesticide.
- Organothiophosphate wikiPageWikiLink Phosphorus_pentasulfide.
- Organothiophosphate wikiPageWikiLink ThioTEPA.
- Organothiophosphate wikiPageWikiLink Thiophosphate.
- Organothiophosphate wikiPageWikiLinkText "Organothiophosphate".
- Organothiophosphate wikiPageWikiLinkText "organothiophosphate".
- Organothiophosphate wikiPageUsesTemplate Template:Gallery.
- Organothiophosphate wikiPageUsesTemplate Template:MeshName.
- Organothiophosphate wikiPageUsesTemplate Template:Organic-compound-stub.
- Organothiophosphate subject Category:Phosphorothioates.
- Organothiophosphate hypernym Subclass.
- Organothiophosphate type Eukaryote.
- Organothiophosphate type Group.
- Organothiophosphate type Group.
- Organothiophosphate type Organophosphoru.
- Organothiophosphate type Oxoanion.
- Organothiophosphate type Organophosphoru.
- Organothiophosphate comment "Organothiophosphates are a subclass of organophosphorus compounds. Many of these compounds are used as pesticides, some have medical applications, and some are used as oil additives. They generally have the chemical formula (RO)3PS, [(RO)2P(S)O]-, R(RO)2PS, etc.Oligonucleotide phosphorothioates (OPS) are modified oligonucleotides where one of the oxygen atoms in the phosphate moiety is replaced by sulfur.".
- Organothiophosphate label "Organothiophosphate".
- Organothiophosphate sameAs Q7102101.
- Organothiophosphate sameAs m.0f2s43.
- Organothiophosphate sameAs Q7102101.
- Organothiophosphate wasDerivedFrom Organothiophosphate?oldid=698055746.
- Organothiophosphate depiction Echothiophate.svg.
- Organothiophosphate isPrimaryTopicOf Organothiophosphate.