Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Opioid> ?p ?o }
- Opioid abstract "Opioids are substances that act on opioid receptors to produce morphine-like effects. Opioids include opiates, an older term that refers to such drugs derived from opium, including morphine itself. Other opioids are semi-synthetic and synthetic drugs such as hydrocodone, oxycodone and fentanyl; antagonist drugs such as naloxone and endogenous peptides such as the endorphins. Opioid drugs are predominantly central nervous system agents, most often used medically to relieve pain. The terms opiate and narcotic are sometimes encountered as synonyms for opioid. Opiate is properly limited to the natural alkaloids found in the resin of the Papaver somniferum (opium poppy) although some authorities include semi-synthetic derivatives. Narcotic, derived from numbness or sleep, is now a legal term that refers to cocaine and opioids, and their source materials; it is also loosely applied to any illegal or controlled psychoactive drug. The term has pejorative connotations and its use is generally discouraged.The side effects of opioids may include itchiness, sedation, nausea, respiratory depression, constipation, and euphoria. Tolerance and dependence will develop with continuous use, requiring increasing doses and leading to a withdrawal syndrome upon abrupt discontinuation. The euphoria attracts recreational use; frequent and escalating recreational use of opioids typically results in addiction. Accidental overdose or concurrent use with other depressant drugs commonly results in death from respiratory depression. Because of opioid drugs' reputation for addiction and fatal overdose, most are highly controlled substances.Primarily used for pain relief, including anesthesia, opioids are also approved to suppress cough, suppress diarrhea, treat addiction, reverse opioid overdose, and suppress opioid induced constipation,. Extremely potent opioids are approved only for veterinary use such as immobilizing large mammals. Opioids act by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract. These receptors mediate both the psychoactive and the somatic effects of opioids. Opioid drugs include partial agonists and antagonists, which produce moderate or no effect (respectively) but displace other opioids from binding in those receptors.Opioids are among the world's oldest known drugs. The medical use of the opium poppy predates recorded history; recreational and religious use likewise precedes the common era. In the 19th century morphine was isolated and marketed, and the hypodermic needle invented, introducing rapid, metered administration of the primary active compound. Synthetic opioids were invented, and biological mechanisms discovered in the 20th century. Illicit production, smuggling, and addiction to opioids prompted treaties, laws and policing which have realized limited success. In 2013 between 28 and 38 million people used opioids illicitly (0.6% to 0.8% of the global population between the ages of 15 and 65). In 2011 an estimated 4 million people the United States used opioids recreationally or were dependent on them. Current increased rates of recreational use and addiction are attributed to over-prescription of opioid medications and inexpensive illicit heroin. Conversely, fears about over-prescribing, exaggerated side effects and addiction from opioids are similarly blamed for under-treatment of pain.".
- Opioid wikiPageExternalLink 46549874.
- Opioid wikiPageExternalLink WHO_EMP_MAR_2011.4_eng.pdf.
- Opioid wikiPageExternalLink www.painpillabuse.com.
- Opioid wikiPageExternalLink GLs_Ens_Balance_NOCP_Col_EN_sanend.pdf.
- Opioid wikiPageExternalLink index.html.
- Opioid wikiPageExternalLink watch?v=1IrJk4780gc.
- Opioid wikiPageID "511394".
- Opioid wikiPageLength "139747".
- Opioid wikiPageOutDegree "1066".
- Opioid wikiPageRevisionID "708222265".
- Opioid wikiPageWikiLink (+)-Naloxone.
- Opioid wikiPageWikiLink 1-Iodomorphine.
- Opioid wikiPageWikiLink 14-Cinnamoyloxycodeinone.
- Opioid wikiPageWikiLink 14-Ethoxymetopon.
- Opioid wikiPageWikiLink 14-Hydroxydihydrocodeine.
- Opioid wikiPageWikiLink 14-Methoxymetopon.
- Opioid wikiPageWikiLink 14-Phenylpropoxymetopon.
- Opioid wikiPageWikiLink 18-Methoxycoronaridine.
- Opioid wikiPageWikiLink 2,4-Dinitrophenylmorphine.
- Opioid wikiPageWikiLink 3-Allylfentanyl.
- Opioid wikiPageWikiLink 3-Methylfentanyl.
- Opioid wikiPageWikiLink 3-Methylthiofentanyl.
- Opioid wikiPageWikiLink 4-Fluoropethidine.
- Opioid wikiPageWikiLink 4-Phenylfentanyl.
- Opioid wikiPageWikiLink 5-Guanidinonaltrindole.
- Opioid wikiPageWikiLink 6,14-Endoethenotetrahydrooripavine.
- Opioid wikiPageWikiLink 6-Methylenedihydrodesoxymorphine.
- Opioid wikiPageWikiLink 6-Monoacetylcodeine.
- Opioid wikiPageWikiLink 6-Monoacetylmorphine.
- Opioid wikiPageWikiLink 6β-Naltrexol-d4.
- Opioid wikiPageWikiLink 7-Hydroxymitragynine.
- Opioid wikiPageWikiLink 7-PET.
- Opioid wikiPageWikiLink 7-Spiroindanyloxymorphone.
- Opioid wikiPageWikiLink 8-Carboxamidocyclazocine.
- Opioid wikiPageWikiLink 8-OH-DPAT.
- Opioid wikiPageWikiLink AD-1211.
- Opioid wikiPageWikiLink AH-7921.
- Opioid wikiPageWikiLink AM404.
- Opioid wikiPageWikiLink Accident-proneness.
- Opioid wikiPageWikiLink Acetorphine.
- Opioid wikiPageWikiLink Acetoxyketobemidone.
- Opioid wikiPageWikiLink Acetyldihydrocodeine.
- Opioid wikiPageWikiLink Acetylmorphone.
- Opioid wikiPageWikiLink Acetylpropionylmorphine.
- Opioid wikiPageWikiLink Addiction.
- Opioid wikiPageWikiLink Adrenorphin.
- Opioid wikiPageWikiLink Afghan_morphine.
- Opioid wikiPageWikiLink Afghanistan.
- Opioid wikiPageWikiLink Agonist.
- Opioid wikiPageWikiLink Akuammine.
- Opioid wikiPageWikiLink Alazocine.
- Opioid wikiPageWikiLink Alfentanil.
- Opioid wikiPageWikiLink Alkaloid.
- Opioid wikiPageWikiLink Allodynia.
- Opioid wikiPageWikiLink Allosteric_modulator.
- Opioid wikiPageWikiLink Allylnorpethidine.
- Opioid wikiPageWikiLink Allylprodine.
- Opioid wikiPageWikiLink Alpha-Neoendorphin.
- Opioid wikiPageWikiLink Alphamethylthiofentanyl.
- Opioid wikiPageWikiLink Alvimopan.
- Opioid wikiPageWikiLink Amidorphin.
- Opioid wikiPageWikiLink Amphetamine.
- Opioid wikiPageWikiLink Analgesic.
- Opioid wikiPageWikiLink Anandamide.
- Opioid wikiPageWikiLink Anesthesia.
- Opioid wikiPageWikiLink Anileridine.
- Opioid wikiPageWikiLink Anticonvulsant.
- Opioid wikiPageWikiLink Antihistamine.
- Opioid wikiPageWikiLink Apomorphine.
- Opioid wikiPageWikiLink Appetite.
- Opioid wikiPageWikiLink Arcuate_nucleus.
- Opioid wikiPageWikiLink Area_postrema.
- Opioid wikiPageWikiLink Arthritis.
- Opioid wikiPageWikiLink Azaprocin.
- Opioid wikiPageWikiLink BD-1047.
- Opioid wikiPageWikiLink BDPC.
- Opioid wikiPageWikiLink BIMU8.
- Opioid wikiPageWikiLink BRL-52537.
- Opioid wikiPageWikiLink BU-48.
- Opioid wikiPageWikiLink BW373U86.
- Opioid wikiPageWikiLink Back_pain.
- Opioid wikiPageWikiLink Barbiturate.
- Opioid wikiPageWikiLink Benzethidine.
- Opioid wikiPageWikiLink Benzodiazepine.
- Opioid wikiPageWikiLink Benzylmorphine.
- Opioid wikiPageWikiLink Beta-Endorphin.
- Opioid wikiPageWikiLink Beta-Methylfentanyl.
- Opioid wikiPageWikiLink Betahydroxyfentanyl.
- Opioid wikiPageWikiLink Betahydroxythiofentanyl.
- Opioid wikiPageWikiLink Bezitramide.
- Opioid wikiPageWikiLink Biological_half-life.
- Opioid wikiPageWikiLink Bisacodyl.
- Opioid wikiPageWikiLink Blood–brain_barrier.
- Opioid wikiPageWikiLink Bone_fracture.
- Opioid wikiPageWikiLink Bradycardia.
- Opioid wikiPageWikiLink Brainstem.
- Opioid wikiPageWikiLink Bremazocine.
- Opioid wikiPageWikiLink Brifentanil.
- Opioid wikiPageWikiLink Bromadoline.