Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Oncolytic_virus> ?p ?o }
- Oncolytic_virus abstract "An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by lysis, they release new infectious virus particles to help destroy the remaining tumour. Oncolytic viruses are thought not only to cause direct destruction of the tumour cells, but also to stimulate host anti-tumour immune responses.The potential of viruses as anti-cancer agents was first realised in the early twentieth century, although coordinated research efforts did not begin until the 1960s. A number of viruses including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus and vaccinia have now been clinically tested as oncolytic agents. Most current oncolytic viruses are engineered for tumour selectivity, although there are naturally occurring examples such as reovirus and the SVV-001 Seneca Valley virus, resulting in clinical trials.As of 2011, only limited human trials had been performed.Nevertheless, the drug talimogene laherparepvec (OncoVex, T-VEC) recently (Jan 2012) reported the first positive interim Phase III clinical trial results for an oncolytic virus, making it likely that it will also be the first one approved for use (for the treatment of advanced melanoma). However, skeptics have questioned the clinical relevance of this interim data citing that the awaited overall survival data will be the final judgement and that it is likely that patient benefit will be maximised in combination with other therapies, which this trial did not test. 2015 update: In a combined decision, members of the FDA's Oncologic Drugs Advisory Committee (ODAC) and Cellular, Tissue and Gene Therapies Advisory Committee (CTGTAC) voted 22-1 to recommend approval of the oncolytic immunotherapy talimogene laherparepvec (T-VEC) as a treatment for patients with advanced melanoma. A final approval decision from the FDA is scheduled by October 27, 2015. Approved in Latvia oncolytic virus RIGVIR was registered in Georgia in February 2015. Melanoma Research published new data on RIGVIR efficacy, showing that early stage melanoma patients treated with oncolytic virus RIGVIR had 4.39–6.57-fold lower mortality than those, who according to melanoma treatment guidelines did not receive virotherapy and were only observed.".
- Oncolytic_virus wikiPageExternalLink twiv-124-viruses-that-make-you-better.
- Oncolytic_virus wikiPageExternalLink twiv-131-a-reostat-for-cancer.
- Oncolytic_virus wikiPageExternalLink twiv-142-viral-oinkotherapy.
- Oncolytic_virus wikiPageExternalLink twiv-156-armed-and-targeted-killer-meta-analysis.
- Oncolytic_virus wikiPageExternalLink twiv-298.
- Oncolytic_virus wikiPageID "1723667".
- Oncolytic_virus wikiPageLength "76229".
- Oncolytic_virus wikiPageOutDegree "164".
- Oncolytic_virus wikiPageRevisionID "706505488".
- Oncolytic_virus wikiPageWikiLink 3.
- Oncolytic_virus wikiPageWikiLink Adenoviridae.
- Oncolytic_virus wikiPageWikiLink Aina_Muceniece.
- Oncolytic_virus wikiPageWikiLink Amgen.
- Oncolytic_virus wikiPageWikiLink Angiogenesis.
- Oncolytic_virus wikiPageWikiLink Antibody.
- Oncolytic_virus wikiPageWikiLink Antigen.
- Oncolytic_virus wikiPageWikiLink Bacteriophage.
- Oncolytic_virus wikiPageWikiLink Beta-galactosidase.
- Oncolytic_virus wikiPageWikiLink Beta-glucuronidase.
- Oncolytic_virus wikiPageWikiLink Bevacizumab.
- Oncolytic_virus wikiPageWikiLink Brain_tumor.
- Oncolytic_virus wikiPageWikiLink Burkitts_lymphoma.
- Oncolytic_virus wikiPageWikiLink CGTG-102.
- Oncolytic_virus wikiPageWikiLink Cancer_cell.
- Oncolytic_virus wikiPageWikiLink Cancer_vaccine.
- Oncolytic_virus wikiPageWikiLink Category:Biotechnology.
- Oncolytic_virus wikiPageWikiLink Category:Emerging_technologies.
- Oncolytic_virus wikiPageWikiLink Category:Experimental_cancer_treatments.
- Oncolytic_virus wikiPageWikiLink Category:Virotherapy.
- Oncolytic_virus wikiPageWikiLink Category:Viruses.
- Oncolytic_virus wikiPageWikiLink Cell_cycle.
- Oncolytic_virus wikiPageWikiLink Cell_division.
- Oncolytic_virus wikiPageWikiLink Cellular_differentiation.
- Oncolytic_virus wikiPageWikiLink Cervical_cancer.
- Oncolytic_virus wikiPageWikiLink Cisplatin.
- Oncolytic_virus wikiPageWikiLink Clinical_trial.
- Oncolytic_virus wikiPageWikiLink Complement_system.
- Oncolytic_virus wikiPageWikiLink Coxsackievirus.
- Oncolytic_virus wikiPageWikiLink Cytokine.
- Oncolytic_virus wikiPageWikiLink Cytotoxicity.
- Oncolytic_virus wikiPageWikiLink DNA.
- Oncolytic_virus wikiPageWikiLink DNA_replication.
- Oncolytic_virus wikiPageWikiLink Directed_evolution.
- Oncolytic_virus wikiPageWikiLink Enadenotucirev.
- Oncolytic_virus wikiPageWikiLink Enzyme.
- Oncolytic_virus wikiPageWikiLink Escherichia_coli.
- Oncolytic_virus wikiPageWikiLink Food_and_Drug_Administration.
- Oncolytic_virus wikiPageWikiLink G0_phase.
- Oncolytic_virus wikiPageWikiLink GL-ONC1.
- Oncolytic_virus wikiPageWikiLink Gamma_camera.
- Oncolytic_virus wikiPageWikiLink Genetic_engineering.
- Oncolytic_virus wikiPageWikiLink Glioblastoma_multiforme.
- Oncolytic_virus wikiPageWikiLink Glioma.
- Oncolytic_virus wikiPageWikiLink Granulocyte_macrophage_colony-stimulating_factor.
- Oncolytic_virus wikiPageWikiLink Green_fluorescent_protein.
- Oncolytic_virus wikiPageWikiLink Head_and_neck_cancer.
- Oncolytic_virus wikiPageWikiLink Hepatocellular_carcinoma.
- Oncolytic_virus wikiPageWikiLink Herpes_labialis.
- Oncolytic_virus wikiPageWikiLink Herpes_simplex_virus.
- Oncolytic_virus wikiPageWikiLink Hodgkins_lymphoma.
- Oncolytic_virus wikiPageWikiLink Homologous_recombination.
- Oncolytic_virus wikiPageWikiLink I_Am_Legend_(film).
- Oncolytic_virus wikiPageWikiLink Immunization.
- Oncolytic_virus wikiPageWikiLink Immunosuppression.
- Oncolytic_virus wikiPageWikiLink In_vivo.
- Oncolytic_virus wikiPageWikiLink Internal_ribosome_entry_site.
- Oncolytic_virus wikiPageWikiLink Intraperitoneal_injection.
- Oncolytic_virus wikiPageWikiLink Intravenous_therapy.
- Oncolytic_virus wikiPageWikiLink Iodine-131.
- Oncolytic_virus wikiPageWikiLink Isotopes_of_iodine.
- Oncolytic_virus wikiPageWikiLink JX-594.
- Oncolytic_virus wikiPageWikiLink Jack_Williamson.
- Oncolytic_virus wikiPageWikiLink Jennerex.
- Oncolytic_virus wikiPageWikiLink Kupffer_cell.
- Oncolytic_virus wikiPageWikiLink Latvia.
- Oncolytic_virus wikiPageWikiLink Liver.
- Oncolytic_virus wikiPageWikiLink Luciferase.
- Oncolytic_virus wikiPageWikiLink Luciferin.
- Oncolytic_virus wikiPageWikiLink Lysis.
- Oncolytic_virus wikiPageWikiLink Macrophage.
- Oncolytic_virus wikiPageWikiLink Malignancy.
- Oncolytic_virus wikiPageWikiLink Maraba_virus.
- Oncolytic_virus wikiPageWikiLink Matthias_Gromeier.
- Oncolytic_virus wikiPageWikiLink Measles_virus_encoding_the_human_thyroidal_sodium_iodide_symporter_(MV-NIS).
- Oncolytic_virus wikiPageWikiLink Melanoma.
- Oncolytic_virus wikiPageWikiLink Mesothelioma.
- Oncolytic_virus wikiPageWikiLink Metastasis.
- Oncolytic_virus wikiPageWikiLink MicroRNA.
- Oncolytic_virus wikiPageWikiLink Neoplasm.
- Oncolytic_virus wikiPageWikiLink Neuroblastoma.
- Oncolytic_virus wikiPageWikiLink Oncolytic_adenovirus.
- Oncolytic_virus wikiPageWikiLink Oncolytic_herpes_virus.
- Oncolytic_virus wikiPageWikiLink Oncolytic_virus.
- Oncolytic_virus wikiPageWikiLink Oncolytics_Biotech.
- Oncolytic_virus wikiPageWikiLink Oncovirus.
- Oncolytic_virus wikiPageWikiLink P53.
- Oncolytic_virus wikiPageWikiLink Pancreatic_cancer.
- Oncolytic_virus wikiPageWikiLink Phagocytosis.
- Oncolytic_virus wikiPageWikiLink Picornavirus.