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- Nocodazole abstract "Nocodazole is an antineoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules. Microtubules are one type of fibre which constitutes the cytoskeleton, and the dynamic microtubule network has several important roles in the cell, including vesicular transport, forming the mitotic spindle and in cytokinesis. Several drugs including vincristine and colcemid are similar to nocodazole in that they interfere with microtubule polymerization.Interestingly, Nocodazole has been shown to decrease the oncogenic potential of cancer cells via another microtubules-independent mechanisms. Nocodazole stimulates the expression of LATS2 which potently inhibits the Wnt signaling pathway by abrogating the interaction between the Wnt-dependent transcriptional co-factors beta-catenin and BCL9.".
- Nocodazole iupacName "Methyl (5-[2-thienylcarbonyl]-1H-benzimidazol-2-yl".
- Nocodazole thumbnail Nocodazole.png?width=300.
- Nocodazole wikiPageID "501210".
- Nocodazole wikiPageLength "4891".
- Nocodazole wikiPageOutDegree "31".
- Nocodazole wikiPageRevisionID "704592150".
- Nocodazole wikiPageWikiLink Apoptosis.
- Nocodazole wikiPageWikiLink BCL9.
- Nocodazole wikiPageWikiLink Beta-catenin.
- Nocodazole wikiPageWikiLink Category:Benzimidazoles.
- Nocodazole wikiPageWikiLink Category:Carbamates.
- Nocodazole wikiPageWikiLink Category:Cell_biology.
- Nocodazole wikiPageWikiLink Category:Microtubule_inhibitors.
- Nocodazole wikiPageWikiLink Category:Thiophenes.
- Nocodazole wikiPageWikiLink Cell_biology.
- Nocodazole wikiPageWikiLink Cell_cycle.
- Nocodazole wikiPageWikiLink Chemotherapy.
- Nocodazole wikiPageWikiLink Colcemid.
- Nocodazole wikiPageWikiLink Cytokinesis.
- Nocodazole wikiPageWikiLink Cytoskeleton.
- Nocodazole wikiPageWikiLink Eukaryote.
- Nocodazole wikiPageWikiLink Flow_cytometry.
- Nocodazole wikiPageWikiLink G2_phase.
- Nocodazole wikiPageWikiLink Golgi_apparatus.
- Nocodazole wikiPageWikiLink Kinetochore.
- Nocodazole wikiPageWikiLink Metaphase.
- Nocodazole wikiPageWikiLink Microtubule.
- Nocodazole wikiPageWikiLink Mitosis.
- Nocodazole wikiPageWikiLink Polymer.
- Nocodazole wikiPageWikiLink Prometaphase.
- Nocodazole wikiPageWikiLink Rho.
- Nocodazole wikiPageWikiLink Small_GTPase.
- Nocodazole wikiPageWikiLink Spindle_apparatus.
- Nocodazole wikiPageWikiLink Spindle_checkpoint.
- Nocodazole wikiPageWikiLink Vincristine.
- Nocodazole wikiPageWikiLinkText "Nocodazole".
- Nocodazole wikiPageWikiLinkText "nocodazole".
- Nocodazole imagefile "Nocodazole.png".
- Nocodazole iupacname "Methyl".
- Nocodazole name "Nocodazole".
- Nocodazole verifiedfields "changed".
- Nocodazole verifiedrevid "405910037".
- Nocodazole watchedfields "changed".
- Nocodazole wikiPageUsesTemplate Template:Cascite.
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- Nocodazole wikiPageUsesTemplate Template:Chembox_Identifiers.
- Nocodazole wikiPageUsesTemplate Template:Chembox_Properties.
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- Nocodazole wikiPageUsesTemplate Template:Ebicite.
- Nocodazole wikiPageUsesTemplate Template:Fdacite.
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- Nocodazole wikiPageUsesTemplate Template:Reflist.
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- Nocodazole wikiPageUsesTemplate Template:Unreferenced.
- Nocodazole subject Category:Benzimidazoles.
- Nocodazole subject Category:Carbamates.
- Nocodazole subject Category:Cell_biology.
- Nocodazole subject Category:Microtubule_inhibitors.
- Nocodazole subject Category:Thiophenes.
- Nocodazole hypernym Agent.
- Nocodazole type ChemicalCompound.
- Nocodazole type ChemicalSubstance.
- Nocodazole type Amide.
- Nocodazole type Carbamate.
- Nocodazole type Chemical.
- Nocodazole type Ester.
- Nocodazole type Heterocycle.
- Nocodazole type Inhibitor.
- Nocodazole type Toxin.
- Nocodazole type ChemicalObject.
- Nocodazole type Thing.
- Nocodazole type Q11173.
- Nocodazole comment "Nocodazole is an antineoplastic agent which exerts its effect in cells by interfering with the polymerization of microtubules. Microtubules are one type of fibre which constitutes the cytoskeleton, and the dynamic microtubule network has several important roles in the cell, including vesicular transport, forming the mitotic spindle and in cytokinesis.".
- Nocodazole label "Nocodazole".
- Nocodazole sameAs Q2506092.
- Nocodazole sameAs نوکودازول.
- Nocodazole sameAs Nocodazole.
- Nocodazole sameAs m.02hx6_.
- Nocodazole sameAs Нокодазол.
- Nocodazole sameAs Nokodazol.
- Nocodazole sameAs Nokodazol.
- Nocodazole sameAs Q2506092.
- Nocodazole sameAs 诺考达唑.
- Nocodazole wasDerivedFrom Nocodazole?oldid=704592150.
- Nocodazole depiction Nocodazole.png.
- Nocodazole isPrimaryTopicOf Nocodazole.
- Nocodazole name "Nocodazole".