Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Neuropeptide> ?p ?o }
- Neuropeptide abstract "Neuropeptides are small protein-like molecules (peptides) used by neurons to communicate with each other. They are neuronal signaling molecules that influence the activity of the brain in specific ways. Different neuropeptides are involved in a wide range of brain functions, including analgesia, reward, food intake, metabolism, reproduction, social behaviors, learning and memory.Neuropeptides are related to peptide hormones, and in some cases peptides that function in the periphery as hormones also have neuronal functions as neuropeptides. The distinction between neuropeptide and peptide hormone has to do with the cell types that release and respond to the molecule; neuropeptides are secreted from neuronal cells (primarily neurons but also glia for some peptides) and signal to neighboring cells (primarily neurons). In contrast, peptide hormones are secreted from neuroendocrine cells and travel through the blood to distant tissues where they evoke a response. Both neuropeptides and peptide hormones are synthesized by the same sets of enzymes, which include prohormone convertases and carboxypeptidases that selectively cleave the peptide precursor at specific processing sites to generate the bioactive peptides. Neuropeptides modulate neuronal communication by acting on cell surface receptors. Many neuropeptides are co-released with other small-molecule neurotransmitters. The human genome contains about 90 genes that encode precursors of neuropeptides. At present about 100 different peptides are known to be released by different populations of neurons in the mammalian brain. Neurons use many different chemical signals to communicate information, including neurotransmitters, peptides, and gasotransmitters. Peptides are unique among these cell-cell signaling molecules in several respects. One major difference is that peptides are not recycled back into the cell once secreted, unlike many conventional neurotransmitters (glutamate, dopamine, serotonin). Another difference is that after secretion, peptides are modified by extracellular peptidases; in some cases, these extracellular cleavages inactivate the biological activity, but in other cases the extracellular cleavages increase the affinity of a peptide for a particular receptor while decreasing its affinity for another receptor. These extracellular processing events add to the complexity of neuropeptides as cell-cell signaling molecules.Many populations of neurons have distinctive biochemical phenotypes. For example, in one subpopulation of about 3000 neurons in the arcuate nucleus of the hypothalamus, three anorectic peptides are co-expressed: α-melanocyte-stimulating hormone (α-MSH), galanin-like peptide, and cocaine-and-amphetamine-regulated transcript (CART), and in another subpopulation two orexigenic peptides are co-expressed, neuropeptide Y and agouti-related peptide (AGRP). These are not the only peptides in the arcuate nucleus; β-endorphin, dynorphin, enkephalin, galanin, ghrelin, growth-hormone releasing hormone, neurotensin, neuromedin U, and somatostatin are also expressed in subpopulations of arcuate neurons. These peptides are all released centrally and act on other neurons at specific receptors. The neuropeptide Y neurons also make the classical inhibitory neurotransmitter GABA.Invertebrates also have many neuropeptides. CCAP has several functions including regulating heart rate, allatostatin and proctolin regulate food intake and growth, bursicon controls tanning of the cuticle and corazonin has a role in cuticle pigmentation and moulting.Peptide signals play a role in information processing that is different from that of conventional neurotransmitters, and many appear to be particularly associated with specific behaviours. For example, oxytocin and vasopressin have striking and specific effects on social behaviours, including maternal behaviour and pair bonding.".
- Neuropeptide thumbnail Neuropeptide_Y.png?width=300.
- Neuropeptide wikiPageExternalLink npep.
- Neuropeptide wikiPageExternalLink 1.
- Neuropeptide wikiPageExternalLink www.neuropeptides.nl.
- Neuropeptide wikiPageID "984726".
- Neuropeptide wikiPageLength "9047".
- Neuropeptide wikiPageOutDegree "94".
- Neuropeptide wikiPageRevisionID "704054339".
- Neuropeptide wikiPageWikiLink Acetylcholine.
- Neuropeptide wikiPageWikiLink Agouti-related_peptide.
- Neuropeptide wikiPageWikiLink Allatostatin.
- Neuropeptide wikiPageWikiLink Alpha-Melanocyte-stimulating_hormone.
- Neuropeptide wikiPageWikiLink Anorectic.
- Neuropeptide wikiPageWikiLink Arcuate_nucleus.
- Neuropeptide wikiPageWikiLink Beta-Endorphin.
- Neuropeptide wikiPageWikiLink Brain.
- Neuropeptide wikiPageWikiLink Bursicon.
- Neuropeptide wikiPageWikiLink Capsaicin.
- Neuropeptide wikiPageWikiLink Category:Molecular_biology.
- Neuropeptide wikiPageWikiLink Category:Neuropeptides.
- Neuropeptide wikiPageWikiLink Cholecystokinin.
- Neuropeptide wikiPageWikiLink Cocaine_and_amphetamine_regulated_transcript.
- Neuropeptide wikiPageWikiLink Corazonin.
- Neuropeptide wikiPageWikiLink Corticotropin-releasing_hormone.
- Neuropeptide wikiPageWikiLink Crustacean_cardioactive_peptide.
- Neuropeptide wikiPageWikiLink Dendrite.
- Neuropeptide wikiPageWikiLink Dense-core_vesicles.
- Neuropeptide wikiPageWikiLink Dopamine.
- Neuropeptide wikiPageWikiLink Dynorphin.
- Neuropeptide wikiPageWikiLink Enkephalin.
- Neuropeptide wikiPageWikiLink Epinephrine.
- Neuropeptide wikiPageWikiLink G_protein.
- Neuropeptide wikiPageWikiLink Galanin.
- Neuropeptide wikiPageWikiLink Galanin-like_peptide.
- Neuropeptide wikiPageWikiLink Gamma-Aminobutyric_acid.
- Neuropeptide wikiPageWikiLink Gaseous_signaling_molecules.
- Neuropeptide wikiPageWikiLink Genome.
- Neuropeptide wikiPageWikiLink Ghrelin.
- Neuropeptide wikiPageWikiLink Glucagon-like_peptide-1.
- Neuropeptide wikiPageWikiLink Glutamic_acid.
- Neuropeptide wikiPageWikiLink Growth_hormone–releasing_hormone.
- Neuropeptide wikiPageWikiLink Hippocampus.
- Neuropeptide wikiPageWikiLink Hormone.
- Neuropeptide wikiPageWikiLink Hypothalamus.
- Neuropeptide wikiPageWikiLink Metabotropic_receptor.
- Neuropeptide wikiPageWikiLink NOD_mice.
- Neuropeptide wikiPageWikiLink Neuroendocrine_cell.
- Neuropeptide wikiPageWikiLink Neuroglia.
- Neuropeptide wikiPageWikiLink Neuromedin_U.
- Neuropeptide wikiPageWikiLink Neuron.
- Neuropeptide wikiPageWikiLink Neuropeptide_Y.
- Neuropeptide wikiPageWikiLink Neurotensin.
- Neuropeptide wikiPageWikiLink Neurotransmitter.
- Neuropeptide wikiPageWikiLink Norepinephrine.
- Neuropeptide wikiPageWikiLink Nucleus_accumbens.
- Neuropeptide wikiPageWikiLink Orexigenic.
- Neuropeptide wikiPageWikiLink Oxytocin.
- Neuropeptide wikiPageWikiLink Paraventricular_nucleus_of_hypothalamus.
- Neuropeptide wikiPageWikiLink Peptide.
- Neuropeptide wikiPageWikiLink Proctolin.
- Neuropeptide wikiPageWikiLink Sensory_nerve.
- Neuropeptide wikiPageWikiLink Serotonin.
- Neuropeptide wikiPageWikiLink Solitary_nucleus.
- Neuropeptide wikiPageWikiLink Soma.
- Neuropeptide wikiPageWikiLink Somatostatin.
- Neuropeptide wikiPageWikiLink Substance_P.
- Neuropeptide wikiPageWikiLink Supraoptic_nucleus.
- Neuropeptide wikiPageWikiLink Synaptogenesis.
- Neuropeptide wikiPageWikiLink The_Hospital_for_Sick_Children.
- Neuropeptide wikiPageWikiLink Thyrotropin-releasing_hormone.
- Neuropeptide wikiPageWikiLink Vasoactive_intestinal_peptide.
- Neuropeptide wikiPageWikiLink Vasopressin.
- Neuropeptide wikiPageWikiLink Vesicle_(biology_and_chemistry).
- Neuropeptide wikiPageWikiLink File:Neuropeptide_Y.png.
- Neuropeptide wikiPageWikiLinkText "Neuropeptide".
- Neuropeptide wikiPageWikiLinkText "neuropeptide".
- Neuropeptide wikiPageWikiLinkText "non-peptide".
- Neuropeptide wikiPageWikiLinkText "peptide neurotransmitters".
- Neuropeptide wikiPageUsesTemplate Template:Citation_needed.
- Neuropeptide wikiPageUsesTemplate Template:Commons.
- Neuropeptide wikiPageUsesTemplate Template:Neuropeptides.
- Neuropeptide wikiPageUsesTemplate Template:Reflist.
- Neuropeptide wikiPageUsesTemplate Template:Signal_transduction.
- Neuropeptide wikiPageUsesTemplate Template:Unreferenced_section.
- Neuropeptide wikiPageUsesTemplate Template:Use_dmy_dates.
- Neuropeptide wikiPageUsesTemplate Template:Wiktionary.
- Neuropeptide subject Category:Molecular_biology.
- Neuropeptide subject Category:Neuropeptides.
- Neuropeptide hypernym Molecules.
- Neuropeptide type Protein.
- Neuropeptide type Hormone.
- Neuropeptide type Neuropeptide.
- Neuropeptide type Concept.
- Neuropeptide comment "Neuropeptides are small protein-like molecules (peptides) used by neurons to communicate with each other. They are neuronal signaling molecules that influence the activity of the brain in specific ways.".
- Neuropeptide label "Neuropeptide".
- Neuropeptide sameAs Q419968.
- Neuropeptide sameAs Neuropèptid.
- Neuropeptide sameAs دەمارەپێپتاید.
- Neuropeptide sameAs Neuropeptide.