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- Neurohypophysial_hormone abstract "The neurohypophysial hormones form a family of structurally and functionally related peptide hormones. Their main representatives are oxytocin and vasopressin. They are named for being secreted by the neurohypophysis, i.e. the posterior pituitary gland (hypophysis refers to the pituitary gland), itself a neuronal projection from the hypothalamus.Most of the circulating oxytocin and vasopressin hormones are synthesized in magnocellular neurosecretory cells of the supraoptic nucleus and paraventricular nucleus of the hypothalamus. They are then transported in neurosecretory granules along axons within the hypothalamo-neurohypophysial tract by axoplasmic flow to axon terminals forming the pars nervosa of the posterior pituitary. There, they are stored in Herring bodies and can be released into the circulation on the basis of hormonal and synaptic signals with assistance from pituicytes.Vasopressin and oxytocin are also synthesized in the parvocellular neurosecretory cells of the paraventricular nucleus of the hypothalamus, which project to the median eminence, where they are transported and secreted into the hypophyseal portal system to stimulate the anterior pituitary. Thus they can also be considered as hypophysiotropic hormones.Oxytocin mediates contraction of the smooth muscle of the uterus and mammary gland, while vasopressin has antidiuretic action on the kidney, and mediates vasoconstriction of the peripheral vessels. Due to the similarity of the two hormones, there is cross-reaction: oxytocin has a slight antidiuretic function, and high levels of AVP can cause uterine contractions. In common with most active peptides, both hormones are synthesised as larger protein precursors that are enzymatically converted to their mature forms.Members of this family are found in birds, fish, reptiles and amphibians (mesotocin, isotocin, valitocin, glumitocin, aspargtocin, vasotocin, seritocin, asvatocin, phasvatocin), in worms (annetocin, nematocin), octopuses (cephalotocin), Locusta migratoria (Migratory locust) (locupressin or neuropeptide F1/F2) and in molluscs (conopressins G and S).".
- Neurohypophysial_hormone symbol "Hormone_4".
- Neurohypophysial_hormone symbol "Hormone_5".
- Neurohypophysial_hormone thumbnail PDB_1xy1_EBI.jpg?width=300.
- Neurohypophysial_hormone wikiPageID "29126466".
- Neurohypophysial_hormone wikiPageLength "6443".
- Neurohypophysial_hormone wikiPageOutDegree "28".
- Neurohypophysial_hormone wikiPageRevisionID "687588353".
- Neurohypophysial_hormone wikiPageWikiLink Anterior_pituitary.
- Neurohypophysial_hormone wikiPageWikiLink Antidiuretic.
- Neurohypophysial_hormone wikiPageWikiLink Axon_terminal.
- Neurohypophysial_hormone wikiPageWikiLink Axoplasmic_transport.
- Neurohypophysial_hormone wikiPageWikiLink Category:Hormones.
- Neurohypophysial_hormone wikiPageWikiLink Category:Peptides.
- Neurohypophysial_hormone wikiPageWikiLink Category:Protein_families.
- Neurohypophysial_hormone wikiPageWikiLink Herring_bodies.
- Neurohypophysial_hormone wikiPageWikiLink Hypophyseal_portal_system.
- Neurohypophysial_hormone wikiPageWikiLink Hypophysiotropic_hormone.
- Neurohypophysial_hormone wikiPageWikiLink Hypothalamus.
- Neurohypophysial_hormone wikiPageWikiLink Isotocin.
- Neurohypophysial_hormone wikiPageWikiLink Magnocellular_neurosecretory_cell.
- Neurohypophysial_hormone wikiPageWikiLink Median_eminence.
- Neurohypophysial_hormone wikiPageWikiLink Mesotocin.
- Neurohypophysial_hormone wikiPageWikiLink Migratory_locust.
- Neurohypophysial_hormone wikiPageWikiLink Oxytocin.
- Neurohypophysial_hormone wikiPageWikiLink Paraventricular_nucleus_of_hypothalamus.
- Neurohypophysial_hormone wikiPageWikiLink Parvocellular_neurosecretory_cell.
- Neurohypophysial_hormone wikiPageWikiLink Peptide_hormone.
- Neurohypophysial_hormone wikiPageWikiLink Pituicyte.
- Neurohypophysial_hormone wikiPageWikiLink Pituitary_gland.
- Neurohypophysial_hormone wikiPageWikiLink Pituitary_stalk.
- Neurohypophysial_hormone wikiPageWikiLink Posterior_pituitary.
- Neurohypophysial_hormone wikiPageWikiLink Protein_family.
- Neurohypophysial_hormone wikiPageWikiLink Smooth_muscle_tissue.
- Neurohypophysial_hormone wikiPageWikiLink Supraoptic_nucleus.
- Neurohypophysial_hormone wikiPageWikiLink Vasopressin.
- Neurohypophysial_hormone wikiPageWikiLinkText "Neurohypophysial hormone".
- Neurohypophysial_hormone wikiPageWikiLinkText "hormones of the posterior pituitary".
- Neurohypophysial_hormone wikiPageWikiLinkText "neurohypophysial hormone".
- Neurohypophysial_hormone caption "crystal structure analysis of deamino-oxytocin. conformational flexibility and receptor binding".
- Neurohypophysial_hormone caption "solution structure of the monomeric form of a mutant unliganded bovine neurophysin, minimized average structure".
- Neurohypophysial_hormone interpro "IPR000981".
- Neurohypophysial_hormone interpro "IPR022423".
- Neurohypophysial_hormone name "Neurohypophysial hormones, C-terminal Domain".
- Neurohypophysial_hormone name "Neurohypophysial hormones, N-terminal Domain".
- Neurohypophysial_hormone pfam "PF00184".
- Neurohypophysial_hormone pfam "PF00220".
- Neurohypophysial_hormone prosite "PDOC00237".
- Neurohypophysial_hormone scop "1".
- Neurohypophysial_hormone symbol "Hormone_4".
- Neurohypophysial_hormone symbol "Hormone_5".
- Neurohypophysial_hormone wikiPageUsesTemplate Template:Infobox_protein_family.
- Neurohypophysial_hormone wikiPageUsesTemplate Template:InterPro_content.
- Neurohypophysial_hormone wikiPageUsesTemplate Template:Reflist.
- Neurohypophysial_hormone subject Category:Hormones.
- Neurohypophysial_hormone subject Category:Peptides.
- Neurohypophysial_hormone subject Category:Protein_families.
- Neurohypophysial_hormone type Biomolecule.
- Neurohypophysial_hormone type Protein.
- Neurohypophysial_hormone type Biomolecule.
- Neurohypophysial_hormone type Chemical.
- Neurohypophysial_hormone type Peptide.
- Neurohypophysial_hormone type Thing.
- Neurohypophysial_hormone type Q206229.
- Neurohypophysial_hormone type Q8054.
- Neurohypophysial_hormone comment "The neurohypophysial hormones form a family of structurally and functionally related peptide hormones. Their main representatives are oxytocin and vasopressin. They are named for being secreted by the neurohypophysis, i.e.".
- Neurohypophysial_hormone label "Neurohypophysial hormone".
- Neurohypophysial_hormone sameAs Q7002289.
- Neurohypophysial_hormone sameAs هرمونات_نخامية_عصبية.
- Neurohypophysial_hormone sameAs m.0dlkfn9.
- Neurohypophysial_hormone sameAs Q7002289.
- Neurohypophysial_hormone wasDerivedFrom Neurohypophysial_hormone?oldid=687588353.
- Neurohypophysial_hormone depiction PDB_1xy1_EBI.jpg.
- Neurohypophysial_hormone isPrimaryTopicOf Neurohypophysial_hormone.