Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Neuraminidase_inhibitor> ?p ?o }
Showing triples 1 to 63 of
63
with 100 triples per page.
- Neuraminidase_inhibitor abstract "Neuraminidase inhibitors (NAIs) are a class of drugs which block the neuraminidase enzyme. They are commonly used as antiviral drugs because they block the function of viral neuraminidases of the influenza virus, by preventing its reproduction by budding from the host cell. Oseltamivir (Tamiflu) a prodrug, Zanamivir (Relenza), Laninamivir (Inavir), and Peramivir belong to this class. Unlike the M2 inhibitors, which work only against the influenza A, neuraminidase inhibitors act against both influenza A and influenza B. The neuraminidase inhibitors oseltamivir and zanamivir were approved in the US and Europe for treatment and prevention of influenza A and B. Peramivir acts by strongly binding to the neuraminidase of the influenza viruses and inhibits activation of neuraminidase much longer than Oseltamivir or Zanamivir. However, Laninamivir in the cells is slowly released into the respiratory tract, resulting in long-lasting anti-influenza virus activity. Thus the mechanism of the long-lasting activity of laninamivir is basically different from that of Peramivir.The efficacy was highly debated in recent years. However, after the pandemic caused by H1N1 in 2009, the effectiveness of early treatment with neuraminidase inhibitors in reducing serious cases and deaths was reported in various countries. In countries where treatment of influenza like illness are done using neuraminidase inhibitors on a national level, statistical reports show a low fatality record for symptomatic illness because of the universal implementation of early treatment using NAIs. Although oseltamivir is widely used in these countries there has been no outbreaks caused by oseltamivir-resistant viruses and also no serious illness caused by oseltamivir-resistant viruse has ever been reported. The United States Centers for Disease Control continues to recommend the use of oseltamavir treatment for people at high risk for complications and the elderly and those at lower risk who present within 48 hours of first symptoms of infection.Common side effects include nausea and vomiting. The abnormal behaviours of children after taking oseltamivir that have been reported may be an extension of delirium or hallucinations caused by influenza. It occurs in the early stages of the illness, such as within 48 hours after onset of the illness. Therefore, children with influenza are advised to be observed by their parents until 48 hours after the onset of the influenza illness, regardless of whether the child is treated with NAIs.".
- Neuraminidase_inhibitor thumbnail Zanamivir_structure.svg?width=300.
- Neuraminidase_inhibitor wikiPageID "2853911".
- Neuraminidase_inhibitor wikiPageLength "11053".
- Neuraminidase_inhibitor wikiPageOutDegree "43".
- Neuraminidase_inhibitor wikiPageRevisionID "708291981".
- Neuraminidase_inhibitor wikiPageWikiLink Antiviral_drug.
- Neuraminidase_inhibitor wikiPageWikiLink Budding.
- Neuraminidase_inhibitor wikiPageWikiLink Category:Carbohydrate_chemistry.
- Neuraminidase_inhibitor wikiPageWikiLink Category:Neuraminidase_inhibitors.
- Neuraminidase_inhibitor wikiPageWikiLink Discovery_and_development_of_neuraminidase_inhibitors.
- Neuraminidase_inhibitor wikiPageWikiLink Drug.
- Neuraminidase_inhibitor wikiPageWikiLink Influenza_A_virus.
- Neuraminidase_inhibitor wikiPageWikiLink Influenza_A_virus_subtype_H1N1.
- Neuraminidase_inhibitor wikiPageWikiLink Influenzavirus_B.
- Neuraminidase_inhibitor wikiPageWikiLink Laninamivir.
- Neuraminidase_inhibitor wikiPageWikiLink M2_proton_channel.
- Neuraminidase_inhibitor wikiPageWikiLink Natural_product.
- Neuraminidase_inhibitor wikiPageWikiLink Nausea.
- Neuraminidase_inhibitor wikiPageWikiLink Neuraminidase.
- Neuraminidase_inhibitor wikiPageWikiLink Oseltamivir.
- Neuraminidase_inhibitor wikiPageWikiLink Peramivir.
- Neuraminidase_inhibitor wikiPageWikiLink Prodrug.
- Neuraminidase_inhibitor wikiPageWikiLink Sambucus_nigra.
- Neuraminidase_inhibitor wikiPageWikiLink Viral_neuraminidase.
- Neuraminidase_inhibitor wikiPageWikiLink Vomiting.
- Neuraminidase_inhibitor wikiPageWikiLink Zanamivir.
- Neuraminidase_inhibitor wikiPageWikiLink File:Laninamivir.svg.
- Neuraminidase_inhibitor wikiPageWikiLink File:Oseltamivir.svg.
- Neuraminidase_inhibitor wikiPageWikiLink File:Peramivir.svg.
- Neuraminidase_inhibitor wikiPageWikiLink File:Zanamivir_structure.svg.
- Neuraminidase_inhibitor wikiPageWikiLinkText "Neuraminidase Inhibitor".
- Neuraminidase_inhibitor wikiPageWikiLinkText "Neuraminidase inhibitor".
- Neuraminidase_inhibitor wikiPageWikiLinkText "neuraminidase inhibitor".
- Neuraminidase_inhibitor wikiPageUsesTemplate Template:Enzyme_inhibition.
- Neuraminidase_inhibitor wikiPageUsesTemplate Template:Merge_from.
- Neuraminidase_inhibitor wikiPageUsesTemplate Template:RNA_antivirals.
- Neuraminidase_inhibitor subject Category:Carbohydrate_chemistry.
- Neuraminidase_inhibitor subject Category:Neuraminidase_inhibitors.
- Neuraminidase_inhibitor hypernym Drugs.
- Neuraminidase_inhibitor type Agent.
- Neuraminidase_inhibitor type Drug.
- Neuraminidase_inhibitor type Agent.
- Neuraminidase_inhibitor type Carbohydrate.
- Neuraminidase_inhibitor type Inhibitor.
- Neuraminidase_inhibitor type Concept.
- Neuraminidase_inhibitor comment "Neuraminidase inhibitors (NAIs) are a class of drugs which block the neuraminidase enzyme. They are commonly used as antiviral drugs because they block the function of viral neuraminidases of the influenza virus, by preventing its reproduction by budding from the host cell. Oseltamivir (Tamiflu) a prodrug, Zanamivir (Relenza), Laninamivir (Inavir), and Peramivir belong to this class.".
- Neuraminidase_inhibitor label "Neuraminidase inhibitor".
- Neuraminidase_inhibitor sameAs Q425196.
- Neuraminidase_inhibitor sameAs مثبطات_نورامينيداز.
- Neuraminidase_inhibitor sameAs Inhibitor_neuraminidázy.
- Neuraminidase_inhibitor sameAs Neuraminidase-Hemmer.
- Neuraminidase_inhibitor sameAs Neŭraminidaso-inhibiciiloj.
- Neuraminidase_inhibitor sameAs Inhibiteur_de_la_neuraminidase.
- Neuraminidase_inhibitor sameAs ノイラミニダーゼ阻害薬.
- Neuraminidase_inhibitor sameAs Inibidor_de_neuraminidase.
- Neuraminidase_inhibitor sameAs m.086_7p.
- Neuraminidase_inhibitor sameAs Zaviralec_nevraminidaze.
- Neuraminidase_inhibitor sameAs Chất_ức_chế_neuraminidase.
- Neuraminidase_inhibitor sameAs Q425196.
- Neuraminidase_inhibitor wasDerivedFrom Neuraminidase_inhibitor?oldid=708291981.
- Neuraminidase_inhibitor depiction Zanamivir_structure.svg.
- Neuraminidase_inhibitor isPrimaryTopicOf Neuraminidase_inhibitor.