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- Nesprin abstract "The Nesprins (nuclear envelope spectrin repeat proteins) are a family of proteins that are found primarily in the outer nuclear membrane, as well as other subcellular compartments. They contain a C-terminal KASH transmembrane domain and are part of the LINC complex (Linker of Nucleoskeleton and Cytoskeleton) which is a protein network that associates the nuclear envelope (the membrane surrounding the nucleus) to the cytoskeleton, outside the nucleus, and the nuclear lamina, inside the nucleus. Nesprin-1 and -2 bind to the actin filaments. Nesprin-3 binds to plectin, which is bound to the intermediate filaments, while nesprin-4 interacts with kinesin-1.Nesprin mediated connections to the cytoskeleton provides mechanosensory functions in cells, as the absence or disruption of Nesprin family members at the nuclear envelope interferes with the cell's ability to sense and respond to mechanical challenges.".
- Nesprin wikiPageID "16088989".
- Nesprin wikiPageLength "3888".
- Nesprin wikiPageOutDegree "10".
- Nesprin wikiPageRevisionID "705613259".
- Nesprin wikiPageWikiLink Category:Protein_families.
- Nesprin wikiPageWikiLink Enaptin.
- Nesprin wikiPageWikiLink Intermediate_filament.
- Nesprin wikiPageWikiLink KASH_domains.
- Nesprin wikiPageWikiLink Kinesin.
- Nesprin wikiPageWikiLink LINC_complex.
- Nesprin wikiPageWikiLink Microfilament.
- Nesprin wikiPageWikiLink Nuclear_membrane.
- Nesprin wikiPageWikiLink Plectin.
- Nesprin wikiPageWikiLink SYNE2.
- Nesprin wikiPageWikiLinkText "nesprin".
- Nesprin wikiPageUsesTemplate Template:Protein-stub.
- Nesprin wikiPageUsesTemplate Template:Reflist.
- Nesprin subject Category:Protein_families.
- Nesprin hypernym Family.
- Nesprin type Biomolecule.
- Nesprin type Biomolecule.
- Nesprin type Nutrient.
- Nesprin comment "The Nesprins (nuclear envelope spectrin repeat proteins) are a family of proteins that are found primarily in the outer nuclear membrane, as well as other subcellular compartments. They contain a C-terminal KASH transmembrane domain and are part of the LINC complex (Linker of Nucleoskeleton and Cytoskeleton) which is a protein network that associates the nuclear envelope (the membrane surrounding the nucleus) to the cytoskeleton, outside the nucleus, and the nuclear lamina, inside the nucleus.".
- Nesprin label "Nesprin".
- Nesprin sameAs Q17130642.
- Nesprin sameAs Nesprin.
- Nesprin sameAs Nesprine.
- Nesprin sameAs m.03qnvz4.
- Nesprin sameAs Q17130642.
- Nesprin wasDerivedFrom Nesprin?oldid=705613259.
- Nesprin isPrimaryTopicOf Nesprin.