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- NACHT_domain abstract "NACHT is an acronym standing for NAIP (neuronal apoptosis inhibitor protein), C2TA (MHC class 2 transcription activator), HET-E (incompatibility locus protein from Podospora anserina) and TP1 (telomerase-associated protein). The NACHT domain is an evolutionarily conserved protein domain.This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription.The NACHT domain contains 300 to 400 amino acids. It is a predicted nucleoside-triphosphatase (NTPase) domain, which is found in animal, fungal and bacterial proteins. The NACHT domain has been named after NAIP, CIITA, HET-E and TP1. It is found in association with other domains, such as the CARD domain (IPR001315), the pyrin domain (IPR004020), the HEAT repeat domain (IPR004155), the WD40 repeat (IPR001680), the leucine-rich repeat (LRR) or the BIR repeat (IPR001370).The NACHT domain consists of seven distinct conserved motifs, including the ATP/GTPase specific P-loop, the Mg2+-binding site (Walker A and B motifs, respectively) and five more specific motifs. The unique features of the NACHT domain include the prevalence of 'tiny' residues (glycine, alanine or serine) directly C-terminal of the Mg2+-coordinating aspartate in the Walker B motif, in place of a second acidic residue prevalent in other NTPases. A second acidic residue is typically found in the NACHT-containing proteins two positions downstream. Furthermore, the distal motif VII contains a conserved pattern of polar, aromatic and hydrophobic residues that is not seen in any other NTPase family.".
- NACHT_domain symbol "NACHT".
- NACHT_domain wikiPageID "27701317".
- NACHT_domain wikiPageLength "2925".
- NACHT_domain wikiPageOutDegree "41".
- NACHT_domain wikiPageRevisionID "647751438".
- NACHT_domain wikiPageWikiLink Amino_acid.
- NACHT_domain wikiPageWikiLink Apoptosis.
- NACHT_domain wikiPageWikiLink Bacteria.
- NACHT_domain wikiPageWikiLink CARD_domain.
- NACHT_domain wikiPageWikiLink CIITA.
- NACHT_domain wikiPageWikiLink Category:Protein_domains.
- NACHT_domain wikiPageWikiLink Fungus.
- NACHT_domain wikiPageWikiLink HEAT_repeat_domain.
- NACHT_domain wikiPageWikiLink Inhibitor_of_apoptosis_domain.
- NACHT_domain wikiPageWikiLink Leucine-rich_repeat.
- NACHT_domain wikiPageWikiLink Major_histocompatibility_complex.
- NACHT_domain wikiPageWikiLink NAIP_(gene).
- NACHT_domain wikiPageWikiLink NALP3.
- NACHT_domain wikiPageWikiLink NLRC3.
- NACHT_domain wikiPageWikiLink NLRC4.
- NACHT_domain wikiPageWikiLink NLRC5.
- NACHT_domain wikiPageWikiLink NLRP1.
- NACHT_domain wikiPageWikiLink NLRP10.
- NACHT_domain wikiPageWikiLink NLRP11.
- NACHT_domain wikiPageWikiLink NLRP12.
- NACHT_domain wikiPageWikiLink NLRP13.
- NACHT_domain wikiPageWikiLink NLRP14.
- NACHT_domain wikiPageWikiLink NLRP2.
- NACHT_domain wikiPageWikiLink NLRP4.
- NACHT_domain wikiPageWikiLink NLRP5.
- NACHT_domain wikiPageWikiLink NLRP6.
- NACHT_domain wikiPageWikiLink NLRP7.
- NACHT_domain wikiPageWikiLink NLRP8.
- NACHT_domain wikiPageWikiLink NLRP9.
- NACHT_domain wikiPageWikiLink NLRX1.
- NACHT_domain wikiPageWikiLink NOD1.
- NACHT_domain wikiPageWikiLink NOD2.
- NACHT_domain wikiPageWikiLink NWD1.
- NACHT_domain wikiPageWikiLink Nucleoside-triphosphatase.
- NACHT_domain wikiPageWikiLink Protein.
- NACHT_domain wikiPageWikiLink Protein_domain.
- NACHT_domain wikiPageWikiLink Pyrin_domain.
- NACHT_domain wikiPageWikiLink TEP1.
- NACHT_domain wikiPageWikiLink Transcription_(genetics).
- NACHT_domain wikiPageWikiLink WD40_repeat.
- NACHT_domain wikiPageWikiLink Walker_motifs.
- NACHT_domain wikiPageWikiLinkText "NACHT domain".
- NACHT_domain wikiPageWikiLinkText "NACHT".
- NACHT_domain interpro "IPR007111".
- NACHT_domain name "NACHT domain".
- NACHT_domain pfam "PF05729".
- NACHT_domain prosite "PS50837".
- NACHT_domain symbol "NACHT".
- NACHT_domain wikiPageUsesTemplate Template:InterPro.
- NACHT_domain wikiPageUsesTemplate Template:InterPro_content.
- NACHT_domain wikiPageUsesTemplate Template:Pfam_box.
- NACHT_domain wikiPageUsesTemplate Template:Protein-stub.
- NACHT_domain wikiPageUsesTemplate Template:Protein_domains.
- NACHT_domain wikiPageUsesTemplate Template:Reflist.
- NACHT_domain subject Category:Protein_domains.
- NACHT_domain hypernym Standing.
- NACHT_domain type Biomolecule.
- NACHT_domain type Place.
- NACHT_domain type Protein.
- NACHT_domain type Domain.
- NACHT_domain type Thing.
- NACHT_domain type Q206229.
- NACHT_domain type Q8054.
- NACHT_domain comment "NACHT is an acronym standing for NAIP (neuronal apoptosis inhibitor protein), C2TA (MHC class 2 transcription activator), HET-E (incompatibility locus protein from Podospora anserina) and TP1 (telomerase-associated protein). The NACHT domain is an evolutionarily conserved protein domain.This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription.The NACHT domain contains 300 to 400 amino acids.".
- NACHT_domain label "NACHT domain".
- NACHT_domain sameAs Q6952162.
- NACHT_domain sameAs m.0c3y0dz.
- NACHT_domain sameAs NACHT_domen.
- NACHT_domain sameAs NACHT_domen.
- NACHT_domain sameAs Q6952162.
- NACHT_domain wasDerivedFrom NACHT_domain?oldid=647751438.
- NACHT_domain isPrimaryTopicOf NACHT_domain.