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- Myotonin-protein_kinase abstract "Myotonin-protein kinase (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase (DMK) is an enzyme that in humans is encoded by the DMPK gene.The dmpk gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and the Rho family of kinases. Data obtained by using antibodies that detect specific isoforms of DMPK indicate that the most abundant isoform of DMPK is an 80-kDa protein expressed almost exclusively in smooth, skeletal, and cardiac muscles. This kinase exists both as a membrane-associated and as a soluble form in human left ventricular samples. The different C termini of DMPK that arise from alternative splicing determine its localization to the endoplasmic reticulum, mitochondria, or cytosol in transfected COS-1 cells. ). Among the substrates for DMPK proposed by in vitro studies are phospholemman, the dihydropyridine receptor, and the myosin phosphatase targeting subunit. However, an in vivo demonstration of the phosphorylation of these substrates by DMPK remains to be established, and a link between these substrates and the clinical manifestations of DM is unclear.".
- Myotonin-protein_kinase entrezgene "1760".
- Myotonin-protein_kinase wikiPageExternalLink br.fcgi?book=gene&part=myotonic-d.
- Myotonin-protein_kinase wikiPageID "14289143".
- Myotonin-protein_kinase wikiPageLength "18726".
- Myotonin-protein_kinase wikiPageOutDegree "16".
- Myotonin-protein_kinase wikiPageRevisionID "699094501".
- Myotonin-protein_kinase wikiPageWikiLink CACNB1.
- Myotonin-protein_kinase wikiPageWikiLink Category:EC_2.7.11.
- Myotonin-protein_kinase wikiPageWikiLink Category:Human_proteins.
- Myotonin-protein_kinase wikiPageWikiLink Enzyme.
- Myotonin-protein_kinase wikiPageWikiLink FXYD_family.
- Myotonin-protein_kinase wikiPageWikiLink GTPase.
- Myotonin-protein_kinase wikiPageWikiLink Gene.
- Myotonin-protein_kinase wikiPageWikiLink HSPB2.
- Myotonin-protein_kinase wikiPageWikiLink L-type_calcium_channel.
- Myotonin-protein_kinase wikiPageWikiLink Myogenin.
- Myotonin-protein_kinase wikiPageWikiLink Myotonic_dystrophy.
- Myotonin-protein_kinase wikiPageWikiLink Protein–protein_interaction.
- Myotonin-protein_kinase wikiPageWikiLink RAC1.
- Myotonin-protein_kinase wikiPageWikiLink Rho_family_of_GTPases.
- Myotonin-protein_kinase wikiPageWikiLink threonine-specific_protein_kinase.
- Myotonin-protein_kinase wikiPageWikiLink File:DMPK_CTG_Repeat.jpg.
- Myotonin-protein_kinase wikiPageWikiLinkText "DMPK gene".
- Myotonin-protein_kinase wikiPageWikiLinkText "DMPK".
- Myotonin-protein_kinase wikiPageWikiLinkText "Myotonin-protein kinase".
- Myotonin-protein_kinase wikiPageWikiLinkText "dystrophia myotonica protein kinase".
- Myotonin-protein_kinase wikiPageUsesTemplate Template:Cite_journal.
- Myotonin-protein_kinase wikiPageUsesTemplate Template:Enzymes.
- Myotonin-protein_kinase wikiPageUsesTemplate Template:PBB.
- Myotonin-protein_kinase wikiPageUsesTemplate Template:PDB_Gallery.
- Myotonin-protein_kinase wikiPageUsesTemplate Template:Portal_bar.
- Myotonin-protein_kinase wikiPageUsesTemplate Template:Refbegin.
- Myotonin-protein_kinase wikiPageUsesTemplate Template:Refend.
- Myotonin-protein_kinase wikiPageUsesTemplate Template:Reflist.
- Myotonin-protein_kinase wikiPageUsesTemplate threonine-specific_protein_kinases.
- Myotonin-protein_kinase subject Category:EC_2.7.11.
- Myotonin-protein_kinase subject Category:Human_proteins.
- Myotonin-protein_kinase hypernym Enzyme.
- Myotonin-protein_kinase type Biomolecule.
- Myotonin-protein_kinase type Protein.
- Myotonin-protein_kinase type Redirect.
- Myotonin-protein_kinase type Thing.
- Myotonin-protein_kinase type Q206229.
- Myotonin-protein_kinase type Q8054.
- Myotonin-protein_kinase comment "Myotonin-protein kinase (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase (DMK) is an enzyme that in humans is encoded by the DMPK gene.The dmpk gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and the Rho family of kinases.".
- Myotonin-protein_kinase label "Myotonin-protein kinase".
- Myotonin-protein_kinase sameAs Q17914023.
- Myotonin-protein_kinase sameAs Proteína_quinasa_de_distrofia_miotónica.
- Myotonin-protein_kinase sameAs m.03c_j0l.
- Myotonin-protein_kinase sameAs Q17914023.
- Myotonin-protein_kinase wasDerivedFrom Myotonin-protein_kinase?oldid=699094501.
- Myotonin-protein_kinase isPrimaryTopicOf Myotonin-protein_kinase.