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Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Mitotane> ?p ?o }

• Mitotane abstract "Mitotane, also known as o,p'-DDD (Lysodren), is an antineoplastic medication used in the treatment of adrenocortical carcinoma. It is an isomer of DDD and is a derivative of DDT. Its main use is in those patients who have persistent disease despite surgical resection, those who are not surgical candidates, or those who have metastatic disease. It has been produced by Bristol Myers Squibb SpA but it is marketed as an orphan drug due to the small number of patients in need of it. A 2007 study of 177 patients shows a significant increase in the recurrence-free interval after radical surgery followed by mitotane when compared to surgery alone.Mitotane alters steroid peripheral metabolism, directly suppresses the adrenal cortex and alters cortisone metabolism leading to hypocortisolism. Side effects as reported by Schteinberg et al. include anorexia and nausea (88%), diarrhea (38%), vomiting (23%), decreased memory and ability to concentrate (50%), rash (23%), gynecomastia (50%), arthralgia (19%), and leukopenia (7%).Its trade name is Lysodren.".
• Mitotane atcPrefix "L01".
• Mitotane atcSuffix "XX23".
• Mitotane bioavailability "40.0".
• Mitotane casNumber "53-19-0".
• Mitotane drugbank "DB00648".
• Mitotane fdaUniiCode "78E4J5IB5J".
• Mitotane iupacName "(RS)-1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)-ethyl]-benzene".
• Mitotane pubchem "4211".
• Mitotane thumbnail Mitotane.svg?width=300.
• Mitotane wikiPageExternalLink 53-19-0-eng.php.
• Mitotane wikiPageExternalLink RM%20Scope_B12%20-%2053-19-0_EN.pdf.
• Mitotane wikiPageExternalLink wqjmv74186x57wx1.
• Mitotane wikiPageID "3818785".
• Mitotane wikiPageLength "5468".
• Mitotane wikiPageOutDegree "25".
• Mitotane wikiPageRevisionID "707072755".
• Mitotane wikiPageWikiLink Adrenal_insufficiency.
• Mitotane wikiPageWikiLink Adrenocortical_carcinoma.
• Mitotane wikiPageWikiLink Anorexia_(symptom).
• Mitotane wikiPageWikiLink Arthralgia.
• Mitotane wikiPageWikiLink Bristol-Myers_Squibb.
• Mitotane wikiPageWikiLink Category:Antiglucocorticoids.
• Mitotane wikiPageWikiLink Category:Antineoplastic_drugs.
• Mitotane wikiPageWikiLink Category:Organochlorides.
• Mitotane wikiPageWikiLink Category:Orphan_drugs.
• Mitotane wikiPageWikiLink Category:Steroid_11β-hydroxylase_inhibitors.
• Mitotane wikiPageWikiLink Cushings_disease.
• Mitotane wikiPageWikiLink Cushings_syndrome.
• Mitotane wikiPageWikiLink DDT.
• Mitotane wikiPageWikiLink Diarrhea.
• Mitotane wikiPageWikiLink Dichlorodiphenyldichloroethane.
• Mitotane wikiPageWikiLink Dog.
• Mitotane wikiPageWikiLink Gynecomastia.
• Mitotane wikiPageWikiLink Leukopenia.
• Mitotane wikiPageWikiLink Memory.
• Mitotane wikiPageWikiLink Nausea.
• Mitotane wikiPageWikiLink Orphan_drug.
• Mitotane wikiPageWikiLink Pituitary_gland.
• Mitotane wikiPageWikiLink Racemic_mixture.
• Mitotane wikiPageWikiLink Rash.
• Mitotane wikiPageWikiLink Vomiting.
• Mitotane wikiPageWikiLinkText "Mitotane".
• Mitotane wikiPageWikiLinkText "mitotane".
• Mitotane atcPrefix "L01".
• Mitotane atcSuffix "XX23".
• Mitotane bioavailability "40.0".
• Mitotane c "14".
• Mitotane casNumber "53".
• Mitotane chembl "1670".
• Mitotane chemspiderid "4066".
• Mitotane chirality Racemic_mixture.
• Mitotane cl "4".
• Mitotane drugbank "DB00648".
• Mitotane eliminationHalfLife "1.37376E7".
• Mitotane h "10".
• Mitotane inchi "1".
• Mitotane inchikey "JWBOIMRXGHLCPP-UHFFFAOYAD".
• Mitotane iupacName "-1".
• Mitotane iupharLigand "6957".
• Mitotane kegg "D00420".
• Mitotane legalStatus "Rx-only".
• Mitotane licenceUs "MITOTANE".
• Mitotane medlineplus "a608050".
• Mitotane molecularWeight "320.04".
• Mitotane pregnancyCategory "C".
• Mitotane proteinBound "6.0".
• Mitotane pubchem "4211".
• Mitotane routesOfAdministration "Oral".
• Mitotane smiles "Clc1ccccc1CCCl".
• Mitotane stdinchi "1".
• Mitotane stdinchikey "JWBOIMRXGHLCPP-UHFFFAOYSA-N".
• Mitotane tradename "Lysodren".
• Mitotane unii "780000".
• Mitotane verifiedrevid "462252859".
• Mitotane width "200".
• Mitotane wikiPageUsesTemplate Template:Antiglucocorticoids.
• Mitotane wikiPageUsesTemplate Template:Cascite.
• Mitotane wikiPageUsesTemplate Template:Chemotherapeutic_agents.
• Mitotane wikiPageUsesTemplate Template:Chemspidercite.
• Mitotane wikiPageUsesTemplate Template:Cite_journal.
• Mitotane wikiPageUsesTemplate Template:Drugbankcite.
• Mitotane wikiPageUsesTemplate Template:Drugbox.
• Mitotane wikiPageUsesTemplate Template:Drugs.com.
• Mitotane wikiPageUsesTemplate Template:Ebicite.
• Mitotane wikiPageUsesTemplate Template:Fdacite.
• Mitotane wikiPageUsesTemplate Template:Glucocorticoidics.
• Mitotane wikiPageUsesTemplate Template:Keggcite.
• Mitotane wikiPageUsesTemplate Template:Reflist.
• Mitotane wikiPageUsesTemplate Template:Stdinchicite.
• Mitotane wikiPageUsesTemplate Template:Steroid_hormone_metabolism_modulators.
• Mitotane subject Category:Antiglucocorticoids.
• Mitotane subject Category:Antineoplastic_drugs.
• Mitotane subject Category:Organochlorides.
• Mitotane subject Category:Orphan_drugs.
• Mitotane subject Category:Steroid_11β-hydroxylase_inhibitors.
• Mitotane hypernym Medication.
• Mitotane type ChemicalSubstance.
• Mitotane type Drug.
• Mitotane type Drug.

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