Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Mitochondrial_ROS> ?p ?o }
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- Mitochondrial_ROS abstract "Mitochondrial ROS (mtROS or mROS) are reactive oxygen species (ROS) that are produced by mitochondria. Generation of mitochondrial ROS mainly takes place at the electron transport chain located on the inner mitochondrial membrane during the process of oxidative phosphorylation (OXPHOS). Leakage of electrons at complex I and complex III from electron transport chains leads to partial reduction of oxygen to form superoxide. Subsequently, superoxide is quickly dismutated to hydrogen peroxide by two dismutases including superoxide dismutase 2 (SOD2) in mitochondrial matrix and superoxide dismutase 1 (SOD1) in mitochondrial intermembrane space. Collectively, both superoxide and hydrogen peroxide generated in this process are considered as mitochondrial ROS.Once thought as merely the by-products of cellular metabolism, mitochondrial ROS are increasingly viewed as important signaling molecules. At low levels, mitochondrial ROS are considered to be important for metabolic adaptation as seen in hypoxia. Moderate levels of mitochondrial ROS, stimulated by danger signals such as Toll-like receptor 4 ligand bacterial endotoxin lipopolysaccharide (LPS), are involved in regulating inflammatory response. Finally, high levels of mitochondrial ROS activate apoptosis/autophagy pathways capable of inducing cell death.".
- Mitochondrial_ROS thumbnail Production_of_mitochondrial_ROS,_mitochondrial_ROS.png?width=300.
- Mitochondrial_ROS wikiPageID "38862372".
- Mitochondrial_ROS wikiPageLength "2253".
- Mitochondrial_ROS wikiPageOutDegree "16".
- Mitochondrial_ROS wikiPageRevisionID "678972836".
- Mitochondrial_ROS wikiPageWikiLink Apoptosis.
- Mitochondrial_ROS wikiPageWikiLink Autophagy.
- Mitochondrial_ROS wikiPageWikiLink Category:Free_radicals.
- Mitochondrial_ROS wikiPageWikiLink Category:Mitochondria.
- Mitochondrial_ROS wikiPageWikiLink Category:Oxygen.
- Mitochondrial_ROS wikiPageWikiLink Electron_transport_chain.
- Mitochondrial_ROS wikiPageWikiLink Hydrogen_peroxide.
- Mitochondrial_ROS wikiPageWikiLink Inner_mitochondrial_membrane.
- Mitochondrial_ROS wikiPageWikiLink Lipopolysaccharide.
- Mitochondrial_ROS wikiPageWikiLink Mitochondrial_matrix.
- Mitochondrial_ROS wikiPageWikiLink Oxidative_phosphorylation.
- Mitochondrial_ROS wikiPageWikiLink Reactive_oxygen_species.
- Mitochondrial_ROS wikiPageWikiLink SOD2.
- Mitochondrial_ROS wikiPageWikiLink Superoxide.
- Mitochondrial_ROS wikiPageWikiLink TLR4.
- Mitochondrial_ROS wikiPageWikiLink File:Production_of_mitochondrial_ROS,_mitochondrial_ROS.png.
- Mitochondrial_ROS wikiPageUsesTemplate Template:Genetics-stub.
- Mitochondrial_ROS wikiPageUsesTemplate Template:Orphan.
- Mitochondrial_ROS wikiPageUsesTemplate Template:Reflist.
- Mitochondrial_ROS subject Category:Free_radicals.
- Mitochondrial_ROS subject Category:Mitochondria.
- Mitochondrial_ROS subject Category:Oxygen.
- Mitochondrial_ROS hypernym Species.
- Mitochondrial_ROS type Eukaryote.
- Mitochondrial_ROS type Element.
- Mitochondrial_ROS type Substance.
- Mitochondrial_ROS comment "Mitochondrial ROS (mtROS or mROS) are reactive oxygen species (ROS) that are produced by mitochondria. Generation of mitochondrial ROS mainly takes place at the electron transport chain located on the inner mitochondrial membrane during the process of oxidative phosphorylation (OXPHOS). Leakage of electrons at complex I and complex III from electron transport chains leads to partial reduction of oxygen to form superoxide.".
- Mitochondrial_ROS label "Mitochondrial ROS".
- Mitochondrial_ROS sameAs Q17125553.
- Mitochondrial_ROS sameAs m.0ryv5sr.
- Mitochondrial_ROS sameAs Q17125553.
- Mitochondrial_ROS wasDerivedFrom Mitochondrial_ROS?oldid=678972836.
- Mitochondrial_ROS depiction Production_of_mitochondrial_ROS,_mitochondrial_ROS.png.
- Mitochondrial_ROS isPrimaryTopicOf Mitochondrial_ROS.