Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Microheteroplasmy> ?p ?o }
Showing triples 1 to 31 of
31
with 100 triples per page.
- Microheteroplasmy abstract "In biology, microheteroplasmy is a form of heteroplasmy, a type of mutational damage to mitochondrial DNA. While heteroplasmy in general includes mutations present in any fraction of mitochondrial DNA (from fractions of a percent to almost a hundred percent), microheteroplasmy is the presence of mutations levels of up to about 2−5% of mitochondrial genomes. In human mitochondrial DNA, microheteroplasmy constitutes hundreds of independent mutations in one organism, with each mutation usually found in 1–2% of all mitochondrial genomes.The distinction of microheteroplasmy and more gross heteroplasmy is dictated by technical considerations - classical DNA sequencing of mitochondrial DNA by the use of PCR is capable only of detecting mutations at levels of 10% or more, as a result of which mutations at lower levels were never systematically observed until the work of Lin et al.As it became apparent after the use of Lin's cloning and sequencing strategy, capable of detecting mutations at levels of 1% or less, such low-level heteroplasmy, or microheteroplasmy, is exceedingly common, and is in fact the most common form of mutational damage to human DNA found to date. In aged adults, each copy of mitochondrial DNA has on average 3.3 mutations changing protein structure. This exceeds previous estimates by more than three orders of magnitude.The discovery of microheteroplasmy lends support to the mitochondrial theory of aging, and has already been linked to the causation of Parkinson's disease.".
- Microheteroplasmy wikiPageID "1398111".
- Microheteroplasmy wikiPageLength "3201".
- Microheteroplasmy wikiPageOutDegree "12".
- Microheteroplasmy wikiPageRevisionID "702279783".
- Microheteroplasmy wikiPageWikiLink Category:Mutation.
- Microheteroplasmy wikiPageWikiLink Cloning.
- Microheteroplasmy wikiPageWikiLink DNA_sequencing.
- Microheteroplasmy wikiPageWikiLink Heteroplasmy.
- Microheteroplasmy wikiPageWikiLink Homoplasmy.
- Microheteroplasmy wikiPageWikiLink Human_mitochondrial_genetics.
- Microheteroplasmy wikiPageWikiLink Mitochondrial_DNA.
- Microheteroplasmy wikiPageWikiLink Mutation.
- Microheteroplasmy wikiPageWikiLink Parkinsons_disease.
- Microheteroplasmy wikiPageWikiLink Polymerase_chain_reaction.
- Microheteroplasmy wikiPageWikiLink Protein.
- Microheteroplasmy wikiPageWikiLinkText "Microheteroplasmy".
- Microheteroplasmy wikiPageWikiLinkText "microheteroplasmy".
- Microheteroplasmy wikiPageUsesTemplate Template:Cite_journal.
- Microheteroplasmy wikiPageUsesTemplate Template:Portal_bar.
- Microheteroplasmy wikiPageUsesTemplate Template:Reflist.
- Microheteroplasmy subject Category:Mutation.
- Microheteroplasmy hypernym Form.
- Microheteroplasmy comment "In biology, microheteroplasmy is a form of heteroplasmy, a type of mutational damage to mitochondrial DNA. While heteroplasmy in general includes mutations present in any fraction of mitochondrial DNA (from fractions of a percent to almost a hundred percent), microheteroplasmy is the presence of mutations levels of up to about 2−5% of mitochondrial genomes.".
- Microheteroplasmy label "Microheteroplasmy".
- Microheteroplasmy sameAs Q6839584.
- Microheteroplasmy sameAs Microheteroplasmia.
- Microheteroplasmy sameAs m.04zdsr.
- Microheteroplasmy sameAs Q6839584.
- Microheteroplasmy wasDerivedFrom Microheteroplasmy?oldid=702279783.
- Microheteroplasmy isPrimaryTopicOf Microheteroplasmy.