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- NuRD_complex abstract "In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent chromatin remodeling and histone deacetylase activities. As of 2007, Mi-2/NuRD was the only known protein complex coupling chromatin remodeling ATPase and chromatin deacetylation enzymatic functions.The NuRD complex contains seven subunits: the histone deacetylase core proteins HDAC1 and HDAC2, the histone-binding proteins RbAp46 and RbAp48, the metastasis-associated proteins MTA1 (or MTA2 / MTA3), the methyl-CpG-binding domain protein MBD3 (or MBD2) and the chromodomain-helicase-DNA-binding protein CHD3 (aka Mi-2alpha) or CHD4 (aka Mi-2beta).The histone deacetylases HDAC1 and HDAC2 and the histone binding proteins RbAp48 and RbAp46 form a core complex shared between NuRD and Sin3-histone deacetylase complexes.Overexpression of Mbd3, a subunit of NuRD, inhibits induction of iPSCs. Depletion of Mbd3, on the other hand, improves reprogramming efficiency, that results in deterministic and synchronized iPS cell reprogramming (near 100% efficiency within seven days from mouse and human cells).".
- NuRD_complex wikiPageID "32752424".
- NuRD_complex wikiPageLength "3413".
- NuRD_complex wikiPageOutDegree "20".
- NuRD_complex wikiPageRevisionID "615340256".
- NuRD_complex wikiPageWikiLink Adenosine_triphosphate.
- NuRD_complex wikiPageWikiLink CHD3.
- NuRD_complex wikiPageWikiLink CHD4.
- NuRD_complex wikiPageWikiLink Category:Protein_complexes.
- NuRD_complex wikiPageWikiLink Chromatin_remodeling.
- NuRD_complex wikiPageWikiLink HDAC1.
- NuRD_complex wikiPageWikiLink Histone_deacetylase.
- NuRD_complex wikiPageWikiLink Histone_deacetylase_2.
- NuRD_complex wikiPageWikiLink Induced_pluripotent_stem_cell.
- NuRD_complex wikiPageWikiLink MBD3.
- NuRD_complex wikiPageWikiLink MTA1.
- NuRD_complex wikiPageWikiLink MTA2.
- NuRD_complex wikiPageWikiLink MTA3.
- NuRD_complex wikiPageWikiLink Methyl-CpG-binding_domain_protein_2.
- NuRD_complex wikiPageWikiLink Molecular_biology.
- NuRD_complex wikiPageWikiLink Multiprotein_complex.
- NuRD_complex wikiPageWikiLink RBBP4.
- NuRD_complex wikiPageWikiLink RBBP7.
- NuRD_complex wikiPageWikiLinkText "Mi-2/NuRD complex".
- NuRD_complex wikiPageWikiLinkText "NuRD".
- NuRD_complex wikiPageWikiLinkText "Nucleosome Remodelling and Deacetylating complex (NuRD)".
- NuRD_complex wikiPageUsesTemplate Template:As_of.
- NuRD_complex wikiPageUsesTemplate Template:Dubious.
- NuRD_complex wikiPageUsesTemplate Template:Reflist.
- NuRD_complex subject Category:Protein_complexes.
- NuRD_complex hypernym Group.
- NuRD_complex type Band.
- NuRD_complex type Domain.
- NuRD_complex comment "In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent chromatin remodeling and histone deacetylase activities.".
- NuRD_complex label "Mi-2/NuRD complex".
- NuRD_complex sameAs Q7067708.
- NuRD_complex sameAs m.0h3lq06.
- NuRD_complex sameAs Q7067708.
- NuRD_complex wasDerivedFrom NuRD_complex?oldid=615340256.
- NuRD_complex isPrimaryTopicOf NuRD_complex.