Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Mevastatin> ?p ?o }
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- Mevastatin abstract "Mevastatin (compactin, ML-236B) is a hypolipidemic agent that belongs to the statins class.It was isolated from the mold Penicillium citrinum by Akira Endo in the 1970s, and he identified it as a HMG-CoA reductase inhibitor, i.e., a statin. Mevastatin might be considered the first statin drug; clinical trials on mevastatin were performed in the late 1970s in Japan, but it was never marketed. The first statin drug available to the general public was lovastatin. In vitro, it has antiproliferative properties.A British group isolated the same compound from Penicillium brevicompactum, named it compactin, and published their results in 1976. The British group mentions antifungal properties with no mention of HMG-CoA reductase inhibition.High doses inhibit growth and proliferation of melanoma cells.".
- Mevastatin atcPrefix "none".
- Mevastatin casNumber "73573-88-3".
- Mevastatin chEBI "34848".
- Mevastatin drugbank "DB06693".
- Mevastatin fdaUniiCode "1UQM1K0W9X".
- Mevastatin iupacName "(1S,7R,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate".
- Mevastatin pubchem "64715".
- Mevastatin thumbnail Mevastatin2DCSD.svg?width=300.
- Mevastatin wikiPageID "3384841".
- Mevastatin wikiPageLength "5019".
- Mevastatin wikiPageOutDegree "12".
- Mevastatin wikiPageRevisionID "699713533".
- Mevastatin wikiPageWikiLink Akira_Endo_(biochemist).
- Mevastatin wikiPageWikiLink Category:Lactones.
- Mevastatin wikiPageWikiLink Category:Penicillium.
- Mevastatin wikiPageWikiLink Category:Statins.
- Mevastatin wikiPageWikiLink In_vitro.
- Mevastatin wikiPageWikiLink Lipid-lowering_agent.
- Mevastatin wikiPageWikiLink Lovastatin.
- Mevastatin wikiPageWikiLink Medicinal_fungi.
- Mevastatin wikiPageWikiLink Melanoma.
- Mevastatin wikiPageWikiLink Penicillium_citrinum.
- Mevastatin wikiPageWikiLink Statin.
- Mevastatin wikiPageWikiLinkText "ML236B".
- Mevastatin wikiPageWikiLinkText "Mevastatin".
- Mevastatin wikiPageWikiLinkText "compactin".
- Mevastatin wikiPageWikiLinkText "mevastatin".
- Mevastatin atcPrefix "none".
- Mevastatin c "23".
- Mevastatin casNumber "73573".
- Mevastatin chebi "34848".
- Mevastatin chembl "54440".
- Mevastatin chemspiderid "58262".
- Mevastatin drugbank "DB06693".
- Mevastatin h "34".
- Mevastatin inchi "1".
- Mevastatin inchikey "AJLFOPYRIVGYMJ-INTXDZFKBX".
- Mevastatin iupacName "-8".
- Mevastatin iupharLigand "3031".
- Mevastatin kegg "13963.0".
- Mevastatin molecularWeight "390.513".
- Mevastatin o "5".
- Mevastatin pubchem "64715".
- Mevastatin smiles "O=C[C@@H]CC".
- Mevastatin stdinchi "1".
- Mevastatin stdinchikey "AJLFOPYRIVGYMJ-INTXDZFKSA-N".
- Mevastatin unii "1".
- Mevastatin verifiedfields "changed".
- Mevastatin verifiedrevid "462252043".
- Mevastatin width "200".
- Mevastatin wikiPageUsesTemplate Template:Cascite.
- Mevastatin wikiPageUsesTemplate Template:Chemspidercite.
- Mevastatin wikiPageUsesTemplate Template:Drugbankcite.
- Mevastatin wikiPageUsesTemplate Template:Drugbox.
- Mevastatin wikiPageUsesTemplate Template:Ebicite.
- Mevastatin wikiPageUsesTemplate Template:Fdacite.
- Mevastatin wikiPageUsesTemplate Template:Keggcite.
- Mevastatin wikiPageUsesTemplate Template:Reflist.
- Mevastatin wikiPageUsesTemplate Template:Statins.
- Mevastatin wikiPageUsesTemplate Template:Stdinchicite.
- Mevastatin subject Category:Lactones.
- Mevastatin subject Category:Penicillium.
- Mevastatin subject Category:Statins.
- Mevastatin hypernym Agent.
- Mevastatin type Agent.
- Mevastatin type ChemicalSubstance.
- Mevastatin type Drug.
- Mevastatin type Acene.
- Mevastatin type Agent.
- Mevastatin type Chemical.
- Mevastatin type Drug.
- Mevastatin type Ester.
- Mevastatin type Heterocycle.
- Mevastatin type Inhibitor.
- Mevastatin type Lactone.
- Mevastatin type Teratogen.
- Mevastatin type ChemicalObject.
- Mevastatin type Thing.
- Mevastatin type Q8386.
- Mevastatin comment "Mevastatin (compactin, ML-236B) is a hypolipidemic agent that belongs to the statins class.It was isolated from the mold Penicillium citrinum by Akira Endo in the 1970s, and he identified it as a HMG-CoA reductase inhibitor, i.e., a statin. Mevastatin might be considered the first statin drug; clinical trials on mevastatin were performed in the late 1970s in Japan, but it was never marketed. The first statin drug available to the general public was lovastatin.".
- Mevastatin label "Mevastatin".
- Mevastatin sameAs Q414407.
- Mevastatin sameAs ميفاستاتين.
- Mevastatin sameAs Mevastatin.
- Mevastatin sameAs Mevastatina.
- Mevastatin sameAs Mewastatyna.
- Mevastatin sameAs Mevastatina.
- Mevastatin sameAs m.098tdw.
- Mevastatin sameAs Mevastatin.
- Mevastatin sameAs Mevastatin.
- Mevastatin sameAs เมวาสแตติน.
- Mevastatin sameAs Q414407.
- Mevastatin wasDerivedFrom Mevastatin?oldid=699713533.
- Mevastatin depiction Mevastatin2DCSD.svg.
- Mevastatin isPrimaryTopicOf Mevastatin.