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- Metaphase abstract "Metaphase (from the Greek μετά, \"adjacent\" and φάσις, \"stage\") is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase). These chromosomes, carrying genetic information, align in the equator of the cell before being separated into each of the two daughter cells. Metaphase accounts for approximately 4% of the cell cycle's duration.Preceded by events in prometaphase and followed by anaphase, microtubules formed in prophase have already found and attached themselves to kinetochores in metaphase.In metaphase, the centromeres of the chromosomes convene themselves on the metaphase plate (or equatorial plate), an imaginary line that is equidistant from the two centrosome poles. This even alignment is due to the counterbalance of the pulling powers generated by the opposing kinetochore microtubules, analogous to a tug-of-war between two people of equal strength, ending with the destruction of B cyclin. In certain types of cells, chromosomes do not line up at the metaphase plate and instead move back and forth between the poles randomly, only roughly lining up along the middleline. Early events of metaphase can coincide with the later events of prometaphase, as chromosomes with connected kinetochores will start the events of metaphase individually before other chromosomes with unconnected kinetochores that are still lingering in the events of prometaphase.One of the cell cycle checkpoints occurs during prometaphase and metaphase. Only after all chromosomes have become aligned at the metaphase plate, when every kinetochore is properly attached to a bundle of microtubules, does the cell enter anaphase. It is thought that unattached or improperly attached kinetochores generate a signal to prevent premature progression to anaphase, even if most of the kinetochores have been attached and most of the chromosomes have been aligned. Such a signal creates the mitotic spindle checkpoint. This would be accomplished by regulation of the anaphase-promoting complex, securin, and separase.".
- Metaphase thumbnail Metaphase_chromosomes.jpg?width=300.
- Metaphase wikiPageID "584504".
- Metaphase wikiPageLength "5185".
- Metaphase wikiPageOutDegree "46".
- Metaphase wikiPageRevisionID "706882707".
- Metaphase wikiPageWikiLink Anaphase.
- Metaphase wikiPageWikiLink Anaphase-promoting_complex.
- Metaphase wikiPageWikiLink Ancient_Greek.
- Metaphase wikiPageWikiLink Cancer.
- Metaphase wikiPageWikiLink Category:Cell_cycle.
- Metaphase wikiPageWikiLink Category:Mitosis.
- Metaphase wikiPageWikiLink Cell_(biology).
- Metaphase wikiPageWikiLink Cell_cycle.
- Metaphase wikiPageWikiLink Cell_cycle_checkpoint.
- Metaphase wikiPageWikiLink Centromere.
- Metaphase wikiPageWikiLink Centrosome.
- Metaphase wikiPageWikiLink Chromosomal_translocation.
- Metaphase wikiPageWikiLink Chromosome.
- Metaphase wikiPageWikiLink Chronic_myelogenous_leukemia.
- Metaphase wikiPageWikiLink Comparative_genomic_hybridization.
- Metaphase wikiPageWikiLink Cyclin.
- Metaphase wikiPageWikiLink Cytogenetics.
- Metaphase wikiPageWikiLink Eukaryote.
- Metaphase wikiPageWikiLink Fluorescence_in_situ_hybridization.
- Metaphase wikiPageWikiLink G_banding.
- Metaphase wikiPageWikiLink Giemsa_stain.
- Metaphase wikiPageWikiLink Karyotype.
- Metaphase wikiPageWikiLink Kinetochore.
- Metaphase wikiPageWikiLink Leukemia.
- Metaphase wikiPageWikiLink Malignancy.
- Metaphase wikiPageWikiLink Mepacrine.
- Metaphase wikiPageWikiLink Microtubule.
- Metaphase wikiPageWikiLink Mitosis.
- Metaphase wikiPageWikiLink Mitotic_inhibitor.
- Metaphase wikiPageWikiLink Neoplasm.
- Metaphase wikiPageWikiLink Nucleic_acid_sequence.
- Metaphase wikiPageWikiLink Oncogene.
- Metaphase wikiPageWikiLink Philadelphia_chromosome.
- Metaphase wikiPageWikiLink Prometaphase.
- Metaphase wikiPageWikiLink Prophase.
- Metaphase wikiPageWikiLink Securin.
- Metaphase wikiPageWikiLink Separase.
- Metaphase wikiPageWikiLink Spindle_checkpoint.
- Metaphase wikiPageWikiLink Staining.
- Metaphase wikiPageWikiLink File:Metaphase.svg.
- Metaphase wikiPageWikiLink File:Metaphase_chromosomes.jpg.
- Metaphase wikiPageWikiLink File:NHGRI_human_male_karyotype.png.
- Metaphase wikiPageWikiLinkText "M".
- Metaphase wikiPageWikiLinkText "M-phase".
- Metaphase wikiPageWikiLinkText "Metaphase".
- Metaphase wikiPageWikiLinkText "chromosomal misalignment".
- Metaphase wikiPageWikiLinkText "metaphase II".
- Metaphase wikiPageWikiLinkText "metaphase chromosomes".
- Metaphase wikiPageWikiLinkText "metaphase".
- Metaphase wikiPageUsesTemplate Template:Cell_cycle.
- Metaphase wikiPageUsesTemplate Template:Citation_needed.
- Metaphase wikiPageUsesTemplate Template:Commons_category_inline.
- Metaphase wikiPageUsesTemplate Template:Reflist.
- Metaphase subject Category:Cell_cycle.
- Metaphase subject Category:Mitosis.
- Metaphase hypernym Stage.
- Metaphase type Person.
- Metaphase comment "Metaphase (from the Greek μετά, \"adjacent\" and φάσις, \"stage\") is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase). These chromosomes, carrying genetic information, align in the equator of the cell before being separated into each of the two daughter cells.".
- Metaphase label "Metaphase".
- Metaphase sameAs Q574427.
- Metaphase sameAs Metafaza_(mitoza).
- Metaphase sameAs Metafase.
- Metaphase sameAs Metafáze.
- Metaphase sameAs Metafase.
- Metaphase sameAs متافاز.
- Metaphase sameAs Métaphase.
- Metaphase sameAs Metafaza.
- Metaphase sameAs Metafaz.
- Metaphase sameAs Մետաֆազ.
- Metaphase sameAs Metafase.
- Metaphase sameAs Метафаза.
- Metaphase sameAs Metafazė.
- Metaphase sameAs Метафаза.
- Metaphase sameAs Metafaza.
- Metaphase sameAs Metáfase.
- Metaphase sameAs m.02sj89.
- Metaphase sameAs Metafază.
- Metaphase sameAs Metafaza.
- Metaphase sameAs Метафаза.
- Metaphase sameAs Metafaz.
- Metaphase sameAs Метафаза.
- Metaphase sameAs Q574427.
- Metaphase wasDerivedFrom Metaphase?oldid=706882707.
- Metaphase depiction Metaphase_chromosomes.jpg.
- Metaphase isPrimaryTopicOf Metaphase.