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- Mavoglurant abstract "Mavoglurant (AFQ056) is an experimental drug candidate for the treatment of fragile X syndrome. It exerts its effect as an antagonist of the metabotropic glutamate receptor 5 (mGLU5).Mavoglurant is under development by Novartis and is currently in Phase II and Phase III clinical trials. Phase IIb/III dose finding and evaluation trials for fragile X-syndrome have been discontinued by the end of 2014. Otherwise, it would have been the first drug to treat the underlying disorder instead of the symptoms of fragile X syndrome.Mavoglurant is also in Phase II clinical trials for Levodopa-induced dyskinesia.In 2007, Norvartis had conducted a clinical study to assess its ability of reducing cigarette smoking, but no results had been published up till now. Currently Novartis is conducting a clinical trial with this drug on obsessive compulsive disorder.Novartis discontinued development of mavoglurant for fragile X syndrome in April 2014 following disappointing trial results.".
- Mavoglurant iupacName "Methyl (3aR,4S,7aR)-4-hydroxy-4-[(3-methylphenyl)ethynyl]octahydro-1H-indole-1-carboxylate".
- Mavoglurant thumbnail Mavoglurant.svg?width=300.
- Mavoglurant wikiPageID "34640421".
- Mavoglurant wikiPageLength "6134".
- Mavoglurant wikiPageOutDegree "15".
- Mavoglurant wikiPageRevisionID "670417742".
- Mavoglurant wikiPageWikiLink Basimglurant.
- Mavoglurant wikiPageWikiLink Category:Alcohol.
- Mavoglurant wikiPageWikiLink Category:Alkynes.
- Mavoglurant wikiPageWikiLink Category:Carbamates.
- Mavoglurant wikiPageWikiLink Category:MGlu5_receptor_antagonists.
- Mavoglurant wikiPageWikiLink Category:Methyl_esters.
- Mavoglurant wikiPageWikiLink Drug_development.
- Mavoglurant wikiPageWikiLink Fragile_X_syndrome.
- Mavoglurant wikiPageWikiLink Levodopa-induced_dyskinesia.
- Mavoglurant wikiPageWikiLink MTEP.
- Mavoglurant wikiPageWikiLink Metabotropic_glutamate_receptor_5.
- Mavoglurant wikiPageWikiLink Novartis.
- Mavoglurant wikiPageWikiLink Obsessive–compulsive_disorder.
- Mavoglurant wikiPageWikiLink Receptor_antagonist.
- Mavoglurant wikiPageWikiLinkText "Mavoglurant".
- Mavoglurant wikiPageWikiLinkText "mavoglurant".
- Mavoglurant imagefile "Mavoglurant.svg".
- Mavoglurant imagesize "180".
- Mavoglurant iupacname "Methyl -4-hydroxy-4-[ethynyl]octahydro-1H-indole-1-carboxylate".
- Mavoglurant othernames "AFQ056".
- Mavoglurant wikiPageUsesTemplate Template:Cascite.
- Mavoglurant wikiPageUsesTemplate Template:Chembox.
- Mavoglurant wikiPageUsesTemplate Template:Chembox_Hazards.
- Mavoglurant wikiPageUsesTemplate Template:Chembox_Identifiers.
- Mavoglurant wikiPageUsesTemplate Template:Chembox_Properties.
- Mavoglurant wikiPageUsesTemplate Template:Glutamatergics.
- Mavoglurant wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Mavoglurant wikiPageUsesTemplate Template:Reflist.
- Mavoglurant subject Category:Alcohol.
- Mavoglurant subject Category:Alkynes.
- Mavoglurant subject Category:Carbamates.
- Mavoglurant subject Category:MGlu5_receptor_antagonists.
- Mavoglurant subject Category:Methyl_esters.
- Mavoglurant hypernym Candidate.
- Mavoglurant type ChemicalCompound.
- Mavoglurant type ChemicalSubstance.
- Mavoglurant type Drug.
- Mavoglurant type Person.
- Mavoglurant type Alkyne.
- Mavoglurant type Amide.
- Mavoglurant type Carbamate.
- Mavoglurant type Chemical.
- Mavoglurant type Drug.
- Mavoglurant type Ester.
- Mavoglurant type Hydrocarbon.
- Mavoglurant type ChemicalObject.
- Mavoglurant type Thing.
- Mavoglurant type Q11173.
- Mavoglurant comment "Mavoglurant (AFQ056) is an experimental drug candidate for the treatment of fragile X syndrome. It exerts its effect as an antagonist of the metabotropic glutamate receptor 5 (mGLU5).Mavoglurant is under development by Novartis and is currently in Phase II and Phase III clinical trials. Phase IIb/III dose finding and evaluation trials for fragile X-syndrome have been discontinued by the end of 2014.".
- Mavoglurant label "Mavoglurant".
- Mavoglurant sameAs Q6589598.
- Mavoglurant sameAs ماووگلوران.
- Mavoglurant sameAs m.0j251p7.
- Mavoglurant sameAs Mavoglurant.
- Mavoglurant sameAs Mavoglurant.
- Mavoglurant sameAs Q6589598.
- Mavoglurant wasDerivedFrom Mavoglurant?oldid=670417742.
- Mavoglurant depiction Mavoglurant.svg.
- Mavoglurant isPrimaryTopicOf Mavoglurant.