Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Martin_J._Lohse> ?p ?o }
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- Martin_J._Lohse abstract "Martin J. Lohse, M.D. born 26 August 1956, is a German physician and pharmacologist doing research on G protein-coupled receptors. Since 1993, he is a Professor of Pharmacology at the University of Würzburg, Germany, as well as Chairman of the Rudolf Virchow Center (since 2001). He received his exam in medicine as well as his M.D. from the University of Göttingen, and did research in pharmacology at the University of Heidelberg, Duke University and the GeneCenter in Munich. His research focusses on the role of receptors in heart failure and on the mechanisms of their activation and inactivation. While working with Robert Lefkowitz at Duke University he discovered beta-arrestins, proteins that regulate the function of certain cell surface receptors. He discovered that beta-1 adrenergic receptors and their regulatory G protein-coupled receptor kinases are dysregulated in heart failure. The observation that increased β1-adrenergic receptor levels and signaling cause long-term cardiac damage contributed to the use of beta-blockers in heart failure patients. Further studies by his lab showed that heart failure is accompanied by a specific type of activation of so-called ERK protein kinases (Extracellular signal-regulated kinases). Another regulatory protein, Raf kinase inhibitor protein (RKIP), was shown to exert beneficial effects on cardiac structure and function. Lohse pioneered the use of optical techniques to determine, where and how fast receptors become activated by hormones and neurotransmitters.He was awarded the Leibniz Award in 1999, the Ernst Jung Award for Medicine in 2000, and the Research Achievement Award of the International Society of Heart Research in 2007. From 2003 until 2008 he was a member of the German National Ethics Council. From 2009 to 2015 he was Vice President for Research of the University of Würzburg. Since 2009 he is Vice President of the German Academy of Sciences Leopoldina.".
- Martin_J._Lohse birthDate "1956".
- Martin_J._Lohse birthYear "1956".
- Martin_J._Lohse wikiPageExternalLink html.
- Martin_J._Lohse wikiPageExternalLink www.virchow-zentrum.uni-wuerzburg.de.
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- Martin_J._Lohse wikiPageWikiLink Academy_of_Sciences_Leopoldina.
- Martin_J._Lohse wikiPageWikiLink Arrestin.
- Martin_J._Lohse wikiPageWikiLink Beta-1_adrenergic_receptor.
- Martin_J._Lohse wikiPageWikiLink Beta_blocker.
- Martin_J._Lohse wikiPageWikiLink Category:1956_births.
- Martin_J._Lohse wikiPageWikiLink Category:Duke_University_alumni.
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- Martin_J._Lohse wikiPageWikiLink Category:German_pharmacologists.
- Martin_J._Lohse wikiPageWikiLink Category:German_physicians.
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- Martin_J._Lohse wikiPageWikiLink Category:Living_people.
- Martin_J._Lohse wikiPageWikiLink Category:Officers_Crosses_of_the_Order_of_Merit_of_the_Federal_Republic_of_Germany.
- Martin_J._Lohse wikiPageWikiLink Category:University_of_Göttingen_alumni.
- Martin_J._Lohse wikiPageWikiLink Category:University_of_Würzburg_faculty.
- Martin_J._Lohse wikiPageWikiLink Duke_University.
- Martin_J._Lohse wikiPageWikiLink Extracellular_signal-regulated_kinases.
- Martin_J._Lohse wikiPageWikiLink G_protein-coupled_receptor_kinase.
- Martin_J._Lohse wikiPageWikiLink G_protein–coupled_receptor.
- Martin_J._Lohse wikiPageWikiLink German_Ethics_Council.
- Martin_J._Lohse wikiPageWikiLink Germany.
- Martin_J._Lohse wikiPageWikiLink Gottfried_Wilhelm_Leibniz_Prize.
- Martin_J._Lohse wikiPageWikiLink Göttingen.
- Martin_J._Lohse wikiPageWikiLink Heidelberg.
- Martin_J._Lohse wikiPageWikiLink Munich.
- Martin_J._Lohse wikiPageWikiLink Raf_kinase_inhibitor_protein.
- Martin_J._Lohse wikiPageWikiLink Robert_Lefkowitz.
- Martin_J._Lohse wikiPageWikiLink Rudolf_Virchow_Center.
- Martin_J._Lohse wikiPageWikiLink Würzburg.
- Martin_J._Lohse wikiPageWikiLinkText "Martin J. Lohse".
- Martin_J._Lohse dateOfBirth "1956".
- Martin_J._Lohse name "Lohse, Martin J.".
- Martin_J._Lohse shortDescription "German physician and phamacologist".
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- Martin_J._Lohse description "German physician and phamacologist".
- Martin_J._Lohse description "German physician and phamacologist".
- Martin_J._Lohse subject Category:1956_births.
- Martin_J._Lohse subject Category:Duke_University_alumni.
- Martin_J._Lohse subject Category:Fellows_of_the_German_Academy_of_Sciences_Leopoldina.
- Martin_J._Lohse subject Category:German_pharmacologists.
- Martin_J._Lohse subject Category:German_physicians.
- Martin_J._Lohse subject Category:Heidelberg_University_alumni.
- Martin_J._Lohse subject Category:Living_people.
- Martin_J._Lohse subject Category:Officers_Crosses_of_the_Order_of_Merit_of_the_Federal_Republic_of_Germany.
- Martin_J._Lohse subject Category:University_of_Göttingen_alumni.
- Martin_J._Lohse subject Category:University_of_Würzburg_faculty.
- Martin_J._Lohse hypernym Physician.
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- Martin_J._Lohse type Pharmacologist.
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- Martin_J._Lohse comment "Martin J. Lohse, M.D. born 26 August 1956, is a German physician and pharmacologist doing research on G protein-coupled receptors. Since 1993, he is a Professor of Pharmacology at the University of Würzburg, Germany, as well as Chairman of the Rudolf Virchow Center (since 2001). He received his exam in medicine as well as his M.D. from the University of Göttingen, and did research in pharmacology at the University of Heidelberg, Duke University and the GeneCenter in Munich.".
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- Martin_J._Lohse givenName "Martin J.".
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- Martin_J._Lohse name "Lohse, Martin J.".
- Martin_J._Lohse name "Martin J. Lohse".
- Martin_J._Lohse surname "Lohse".