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- MYO1A abstract "Myosin-Ia is a protein that in humans is encoded by the MYO1A gene.The protein encoded by this gene belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The myosin-1a protein is expressed by enterocytes, the epithelial cells that line the luminal surface of the small intestine. In these cells the myosin-1a protein localizes specifically to the brush border. Experiments indicate that the brush border population of the encoded protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the myosin-1a protein binds to the actin core bundle, which turns over on a much slower timescale.".
- MYO1A entrezgene "4640".
- MYO1A wikiPageID "14880582".
- MYO1A wikiPageLength "6652".
- MYO1A wikiPageOutDegree "11".
- MYO1A wikiPageRevisionID "678956664".
- MYO1A wikiPageWikiLink ATP_hydrolysis.
- MYO1A wikiPageWikiLink Actin.
- MYO1A wikiPageWikiLink Brush_border.
- MYO1A wikiPageWikiLink C-terminus.
- MYO1A wikiPageWikiLink Calmodulin.
- MYO1A wikiPageWikiLink EF_hand.
- MYO1A wikiPageWikiLink Enterocyte.
- MYO1A wikiPageWikiLink Gene.
- MYO1A wikiPageWikiLink Myosin.
- MYO1A wikiPageWikiLink Protein.
- MYO1A wikiPageWikiLinkText "MYO1A".
- MYO1A wikiPageWikiLinkText "myosin 1a".
- MYO1A requireManualInspection "no".
- MYO1A updateCitations "yes".
- MYO1A updatePage "yes".
- MYO1A updateProteinBox "yes".
- MYO1A updateSummary "no".
- MYO1A wikiPageUsesTemplate Template:Cite_journal.
- MYO1A wikiPageUsesTemplate Template:Cytoskeletal_Proteins.
- MYO1A wikiPageUsesTemplate Template:Gene-12-stub.
- MYO1A wikiPageUsesTemplate Template:PBB.
- MYO1A wikiPageUsesTemplate Template:PBB_Controls.
- MYO1A wikiPageUsesTemplate Template:PBB_Further_reading.
- MYO1A wikiPageUsesTemplate Template:Refbegin.
- MYO1A wikiPageUsesTemplate Template:Refend.
- MYO1A wikiPageUsesTemplate Template:Reflist.
- MYO1A hypernym Protein.
- MYO1A type Biomolecule.
- MYO1A type Protein.
- MYO1A type Thing.
- MYO1A type Q206229.
- MYO1A type Q8054.
- MYO1A comment "Myosin-Ia is a protein that in humans is encoded by the MYO1A gene.The protein encoded by this gene belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences.".
- MYO1A label "MYO1A".
- MYO1A sameAs Q18029779.
- MYO1A sameAs m.03h05sn.
- MYO1A sameAs Q18029779.
- MYO1A wasDerivedFrom MYO1A?oldid=678956664.
- MYO1A isPrimaryTopicOf MYO1A.