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- MRN_complex abstract "The MRN complex (MRX complex in yeast) is a protein complex consisting of Mre11, Rad50 and Nbs1 (also known as Nibrin in humans and as Xrs2 in yeast). In eukaryotes, the MRN/X complex plays an important role in the initial processing of double-strand DNA breaks prior to repair by homologous recombination or non-homologous end joining. The MRN complex binds avidly to double-strand breaks both in vitro and in vivo and may serve to tether broken ends prior to repair by non-homologous end joining or to initiate resection prior to repair by homologous recombination. The MRN complex also participates in activating the checkpoint kinase ATM in response to DNA damage. Production of short single-strand oligonucleotides by Mre11 endonuclease activity has been implicated in ATM activation by the MRN complex.".
- MRN_complex wikiPageID "17269927".
- MRN_complex wikiPageLength "4062".
- MRN_complex wikiPageOutDegree "13".
- MRN_complex wikiPageRevisionID "619550531".
- MRN_complex wikiPageWikiLink Ataxia_telangiectasia_mutated.
- MRN_complex wikiPageWikiLink Category:Protein_complexes.
- MRN_complex wikiPageWikiLink DNA_repair.
- MRN_complex wikiPageWikiLink Homologous_recombination.
- MRN_complex wikiPageWikiLink MRE11A.
- MRN_complex wikiPageWikiLink Multiprotein_complex.
- MRN_complex wikiPageWikiLink Nibrin.
- MRN_complex wikiPageWikiLink Non-homologous_end_joining.
- MRN_complex wikiPageWikiLink Rad50.
- MRN_complex wikiPageWikiLinkText "MRN complex".
- MRN_complex wikiPageUsesTemplate Template:Reflist.
- MRN_complex subject Category:Protein_complexes.
- MRN_complex comment "The MRN complex (MRX complex in yeast) is a protein complex consisting of Mre11, Rad50 and Nbs1 (also known as Nibrin in humans and as Xrs2 in yeast). In eukaryotes, the MRN/X complex plays an important role in the initial processing of double-strand DNA breaks prior to repair by homologous recombination or non-homologous end joining.".
- MRN_complex label "MRN complex".
- MRN_complex sameAs Q6717521.
- MRN_complex sameAs m.043q7xq.
- MRN_complex sameAs Комплекс_MRN.
- MRN_complex sameAs Q6717521.
- MRN_complex wasDerivedFrom MRN_complex?oldid=619550531.
- MRN_complex isPrimaryTopicOf MRN_complex.