Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/MODY_3> ?p ?o }
Showing triples 1 to 29 of
29
with 100 triples per page.
- MODY_3 abstract "MODY 3 is a form of maturity onset diabetes of the young.MODY 3 (also known as HNF1A-MODY) is caused by mutations of the HNF1-alpha; gene, a homeobox gene on chromosome 12. This is the most common type of MODY in populations with European ancestry, accounting for about 70% of all cases in Europe. HNF1α is a transcription factor (also known as transcription factor 1, TCF1) that is thought to control a regulatory network (including, among other genes, HNF1α) important for differentiation of beta cells. Mutations of this gene lead to reduced beta cell mass or impaired function. MODY 1 and MODY 3 diabetes are clinically similar. About 70% of people develop this type of diabetes by age 25 years, but it occurs at much later ages in a few. This type of diabetes can often be treated with sulfonylureas with excellent results for decades. However, the loss of insulin secretory capacity is slowly progressive and most eventually need insulin. This is the form of MODY which can most resemble ordinary type 1 diabetes, and one of the incentives for diagnosing it is that insulin may be discontinued or deferred in favor of oral sulfonylureas. Some people treated with insulin for years due to a presumption of type 1 diabetes have been able to switch to pills and discontinue injections. Long-term diabetic complications can occur if the glucose is not adequately controlled.High-sensitivity measurements of CRP may help to distinguish between HNF1A-MODY and other forms of diabetes".
- MODY_3 wikiPageID "22575057".
- MODY_3 wikiPageLength "3027".
- MODY_3 wikiPageOutDegree "5".
- MODY_3 wikiPageRevisionID "678955153".
- MODY_3 wikiPageWikiLink Category:Diabetes.
- MODY_3 wikiPageWikiLink Chromosome_12_(human).
- MODY_3 wikiPageWikiLink HNF1A.
- MODY_3 wikiPageWikiLink Homeobox.
- MODY_3 wikiPageWikiLink Maturity_onset_diabetes_of_the_young.
- MODY_3 wikiPageWikiLinkText "MODY 3".
- MODY_3 wikiPageWikiLinkText "maturity onset diabetes of the young type 3".
- MODY_3 name "MODY 3".
- MODY_3 omim "600496".
- MODY_3 wikiPageUsesTemplate Template:Endocrine-disease-stub.
- MODY_3 wikiPageUsesTemplate Template:Endocrine_pathology.
- MODY_3 wikiPageUsesTemplate Template:Infobox_Disease.
- MODY_3 wikiPageUsesTemplate Template:Reflist.
- MODY_3 wikiPageUsesTemplate coregulator_deficiencies.
- MODY_3 subject Category:Diabetes.
- MODY_3 hypernym Form.
- MODY_3 type Diabete.
- MODY_3 comment "MODY 3 is a form of maturity onset diabetes of the young.MODY 3 (also known as HNF1A-MODY) is caused by mutations of the HNF1-alpha; gene, a homeobox gene on chromosome 12. This is the most common type of MODY in populations with European ancestry, accounting for about 70% of all cases in Europe.".
- MODY_3 label "MODY 3".
- MODY_3 sameAs Q6717003.
- MODY_3 sameAs m.05zk6gh.
- MODY_3 sameAs Q6717003.
- MODY_3 wasDerivedFrom MODY_3?oldid=678955153.
- MODY_3 isPrimaryTopicOf MODY_3.