Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/MECP2> ?p ?o }
- MECP2 abstract "MECP2 (methyl CpG binding protein 2 (Rett syndrome)) is a gene that encodes the protein MECP2. MECP2 appears to be essential for the normal function of nerve cells. The protein seems to be particularly important for mature nerve cells, where it is present in high levels. The MECP2 protein is likely to be involved in turning off (\"repressing\" or \"silencing\") several other genes. This prevents the genes from making proteins when they are not needed. Recent work has shown that MECP2 can also activate other genes. The MECP2 gene is located on the long (q) arm of the X chromosome in band 28 (\"Xq28\"), from base pair 152,808,110 to base pair 152,878,611.DNA methylation is a major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2 (this protein), MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensable in stem cells. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.".
- MECP2 entrezgene "4204".
- MECP2 wikiPageExternalLink mecp2.chw.edu.au.
- MECP2 wikiPageExternalLink carddisp?MECP2.
- MECP2 wikiPageExternalLink www.mecp2.co.uk.
- MECP2 wikiPageExternalLink cms.
- MECP2 wikiPageExternalLink br.fcgi?book=gene&part=mecp2-dup.
- MECP2 wikiPageExternalLink br.fcgi?book=gene&part=rett.
- MECP2 wikiPageExternalLink rettuk.html.
- MECP2 wikiPageExternalLink www.rsrt.org.
- MECP2 wikiPageExternalLink www.rettsyndrome.org.
- MECP2 wikiPageID "3469185".
- MECP2 wikiPageLength "25663".
- MECP2 wikiPageOutDegree "65".
- MECP2 wikiPageRevisionID "701973144".
- MECP2 wikiPageWikiLink Amino_acid.
- MECP2 wikiPageWikiLink Amygdala.
- MECP2 wikiPageWikiLink Androgen_receptor.
- MECP2 wikiPageWikiLink Angelman_syndrome.
- MECP2 wikiPageWikiLink Autism.
- MECP2 wikiPageWikiLink Base_pair.
- MECP2 wikiPageWikiLink Brain.
- MECP2 wikiPageWikiLink CREB1.
- MECP2 wikiPageWikiLink Category:DNA-binding_proteins.
- MECP2 wikiPageWikiLink Category:Genes_on_human_chromosome_X.
- MECP2 wikiPageWikiLink Category:Human_genes.
- MECP2 wikiPageWikiLink Category:Transcription_factors.
- MECP2 wikiPageWikiLink Cell_(biology).
- MECP2 wikiPageWikiLink Central_nervous_system.
- MECP2 wikiPageWikiLink Cerebral_cortex.
- MECP2 wikiPageWikiLink Chemical_synapse.
- MECP2 wikiPageWikiLink Chromatin.
- MECP2 wikiPageWikiLink CpG_site.
- MECP2 wikiPageWikiLink Cytosine.
- MECP2 wikiPageWikiLink DLX_gene_family.
- MECP2 wikiPageWikiLink DNA.
- MECP2 wikiPageWikiLink DNA_methylation.
- MECP2 wikiPageWikiLink Dominance_(genetics).
- MECP2 wikiPageWikiLink Epileptic_seizure.
- MECP2 wikiPageWikiLink Gene.
- MECP2 wikiPageWikiLink Gene_expression.
- MECP2 wikiPageWikiLink Gene_silencing.
- MECP2 wikiPageWikiLink Genes,_Brain_and_Behavior.
- MECP2 wikiPageWikiLink Hippocampus.
- MECP2 wikiPageWikiLink Histone_deacetylase.
- MECP2 wikiPageWikiLink Hypothalamus.
- MECP2 wikiPageWikiLink Locus_coeruleus.
- MECP2 wikiPageWikiLink MBD1.
- MECP2 wikiPageWikiLink MBD3.
- MECP2 wikiPageWikiLink MBD4.
- MECP2 wikiPageWikiLink Methyl-CpG-binding_domain.
- MECP2 wikiPageWikiLink Methyl-CpG-binding_domain_protein_2.
- MECP2 wikiPageWikiLink Methylation.
- MECP2 wikiPageWikiLink MiR-132.
- MECP2 wikiPageWikiLink Neonatal_encephalopathy.
- MECP2 wikiPageWikiLink Neuron.
- MECP2 wikiPageWikiLink Nuclear_receptor_co-repressor_1.
- MECP2 wikiPageWikiLink Paraventricular_nucleus_of_hypothalamus.
- MECP2 wikiPageWikiLink Prevalence.
- MECP2 wikiPageWikiLink Protein.
- MECP2 wikiPageWikiLink Protein–protein_interaction.
- MECP2 wikiPageWikiLink RNA_splicing.
- MECP2 wikiPageWikiLink Rett_syndrome.
- MECP2 wikiPageWikiLink SKI_protein.
- MECP2 wikiPageWikiLink Sex_linkage.
- MECP2 wikiPageWikiLink Single-nucleotide_polymorphism.
- MECP2 wikiPageWikiLink Small_interfering_RNA.
- MECP2 wikiPageWikiLink Systemic_lupus_erythematosus.
- MECP2 wikiPageWikiLink Transcription_factor.
- MECP2 wikiPageWikiLink UBE3A.
- MECP2 wikiPageWikiLink Vasopressin.
- MECP2 wikiPageWikiLink X-inactivation.
- MECP2 wikiPageWikiLink X_chromosome.
- MECP2 wikiPageWikiLinkText "MECP2".
- MECP2 wikiPageWikiLinkText "MeCP2".
- MECP2 wikiPageWikiLinkText "Methyl-CpG-binding protein 2".
- MECP2 wikiPageWikiLinkText "methyl CpG binding protein MeCP2".
- MECP2 wikiPageUsesTemplate Template:Cite_journal.
- MECP2 wikiPageUsesTemplate Template:Ensembl.
- MECP2 wikiPageUsesTemplate Template:PBB.
- MECP2 wikiPageUsesTemplate Template:PDB_Gallery.
- MECP2 wikiPageUsesTemplate Template:Refbegin.
- MECP2 wikiPageUsesTemplate Template:Refend.
- MECP2 wikiPageUsesTemplate Template:Reflist.
- MECP2 subject Category:DNA-binding_proteins.
- MECP2 subject Category:Genes_on_human_chromosome_X.
- MECP2 subject Category:Human_genes.
- MECP2 subject Category:Transcription_factors.
- MECP2 hypernym Gene.
- MECP2 type Biomolecule.
- MECP2 type Protein.
- MECP2 type Factor.
- MECP2 type Redirect.
- MECP2 type Thing.
- MECP2 type Q206229.
- MECP2 type Q8054.
- MECP2 comment "MECP2 (methyl CpG binding protein 2 (Rett syndrome)) is a gene that encodes the protein MECP2. MECP2 appears to be essential for the normal function of nerve cells. The protein seems to be particularly important for mature nerve cells, where it is present in high levels. The MECP2 protein is likely to be involved in turning off (\"repressing\" or \"silencing\") several other genes. This prevents the genes from making proteins when they are not needed.".
- MECP2 label "MECP2".
- MECP2 sameAs Q18028997.
- MECP2 sameAs m.09f3nf.