Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Lumacaftor/ivacaftor> ?p ?o }
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- ivacaftor abstract "Lumacaftor/ivacaftor (brand name Orkambi) is a drug used for the treatment of cystic fibrosis. It is a combination drug that consists of lumacaftor and ivacaftor. In July 2015, the Food and Drug Administration (FDA) approved the drug for people with cystic fibrosis with the F508del mutation and an age of 12 years or older. The approval of the drug was based on clinical trial data.Ivacaftor is considered a CFTR potentiator (increases activity of CFTR protein at the surface of epithelial cell), while lumacaftor is a CFTR corrector (increases trafficking of CFTR protein to the cell surface). The drug has received breakthrough therapy designation from the FDA.In Denmark, it is estimated that if the drug is introduced in the treatment the cost will amount to 2 million Danish krones (approximately 270,000 euro) each year per person. The cost in the United States is approximately $259,000 per person per year. It is sold by Vertex Pharmaceuticals Incorporated.".
- ivacaftor thumbnail Ivacaftor_and_lumacaftor.svg?width=300.
- ivacaftor wikiPageID "47400657".
- ivacaftor wikiPageLength "3524".
- ivacaftor wikiPageOutDegree "16".
- ivacaftor wikiPageRevisionID "704156242".
- ivacaftor wikiPageWikiLink Breakthrough_therapy.
- ivacaftor wikiPageWikiLink Category:Breakthrough_therapy.
- ivacaftor wikiPageWikiLink Category:Combination_drugs.
- ivacaftor wikiPageWikiLink Category:Cystic_fibrosis.
- ivacaftor wikiPageWikiLink Clinical_trial.
- ivacaftor wikiPageWikiLink Combination_drug.
- ivacaftor wikiPageWikiLink Cystic_fibrosis.
- ivacaftor wikiPageWikiLink Cystic_fibrosis_transmembrane_conductance_regulator.
- ivacaftor wikiPageWikiLink Danish_krone.
- ivacaftor wikiPageWikiLink Euro.
- ivacaftor wikiPageWikiLink Food_and_Drug_Administration.
- ivacaftor wikiPageWikiLink Ivacaftor.
- ivacaftor wikiPageWikiLink Lumacaftor.
- ivacaftor wikiPageWikiLink Vertex_Pharmaceuticals.
- ivacaftor wikiPageWikiLink ΔF508.
- ivacaftor wikiPageWikiLinkText "Ivacaftor and lumacaftor".
- ivacaftor wikiPageWikiLinkText "Lumacaftor/ivacaftor".
- ivacaftor wikiPageWikiLinkText "lumacaftor/ivacaftor".
- ivacaftor atcPrefix "R07".
- ivacaftor atcSuffix "AX30".
- ivacaftor class "CFTR potentiator".
- ivacaftor component "Ivacaftor".
- ivacaftor component "Lumacaftor".
- ivacaftor legalUs "Rx-only".
- ivacaftor pregnancyUs "B".
- ivacaftor routesOfAdministration "Oral".
- ivacaftor tradename "Orkambi".
- ivacaftor type "combo".
- ivacaftor width "240".
- ivacaftor wikiPageUsesTemplate Template:Drugs.com.
- ivacaftor wikiPageUsesTemplate Template:Infobox_drug.
- ivacaftor wikiPageUsesTemplate Template:Other_respiratory_system_products.
- ivacaftor wikiPageUsesTemplate Template:Reflist.
- ivacaftor subject Category:Breakthrough_therapy.
- ivacaftor subject Category:Combination_drugs.
- ivacaftor subject Category:Cystic_fibrosis.
- ivacaftor hypernym Drug.
- ivacaftor type ChemicalSubstance.
- ivacaftor type Drug.
- ivacaftor type ChemicalObject.
- ivacaftor type Thing.
- ivacaftor type Q8386.
- ivacaftor comment "Lumacaftor/ivacaftor (brand name Orkambi) is a drug used for the treatment of cystic fibrosis. It is a combination drug that consists of lumacaftor and ivacaftor. In July 2015, the Food and Drug Administration (FDA) approved the drug for people with cystic fibrosis with the F508del mutation and an age of 12 years or older.".
- ivacaftor label "Lumacaftor/ivacaftor".
- ivacaftor wasDerivedFrom ivacaftor?oldid=704156242.
- ivacaftor depiction Ivacaftor_and_lumacaftor.svg.
- ivacaftor isPrimaryTopicOf ivacaftor.