Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/List_of_methylphenidate_analogues> ?p ?o }
- List_of_methylphenidate_analogues abstract "This is a list of methylphenidate (MPH or MPD) analogues. Regular methylphenidate can come in several varieties. Including: the racemate, the enantiopure (dextro or levo) of its stereoisomers; erythro or threo (either + or -) among its diastereoisomers & lastly the isomers S,S; S,R/R,S or R,R. The variant with optimized efficacy is not the usually attested generic or common pharmaceutical brands (e.g. Ritalin, Daytrana etc.) but the (R,R)-dextro-(+)-threo. Which has a binding profile on par with or better than that of cocaine. (Note however the measure of five fold (5×) discrepancy in the entropy of binding at their presumed shared target binding site, which may account for the higher abuse potential of cocaine over methylphenidate despite affinity for associating; i.e the latter dissociates more readily once bound despite efficacy for binding).Also of note is that methylphenidate in demethylated form is acidic; a conformation known as ritalinic acid. This gives the potential to yield a conjugate salt form effectively protonated by a salt nearly chemically duplicate/identical to its own structure; creating a \"methylphenidate ritalinate\".The carboxymethyl (methyl acetate) has sometimes been replaced with similar length ketones to increase duration. For instance, the methoxycarbonyl has had examples of having been replaced with an alkyl group (such as Kozikowski showed with RTI-31 n-propyl residue. c.f.)Desoxypipradrol (and thus Pipradrol, including such derivatives as AL-1095, Diphemethoxidine, SCH-5472 & D2PM), and even mefloquine, 2-benzylpiperidine & rimiterol could be considered vaguely related structurally, with the former ones also functionally so, as loosely analogous compounds.Enpiroline is one further example, loosely related by being based on the 2-benzylpiperidine skeleton, although in its case it is actually heteroaromatic; also of note are etoxadrol and dioxadrol.Pethidine (Meperidine) is a loose structural analog (being rather between methylphenidate and certain piperidine phenyltropanes) which, though considered functionally an opioid, is also shown to have dopaminergic reuptake qualities.".
- List_of_methylphenidate_analogues thumbnail Methylphenidate3Dan.gif?width=300.
- List_of_methylphenidate_analogues wikiPageExternalLink 527.full.
- List_of_methylphenidate_analogues wikiPageExternalLink abstract.
- List_of_methylphenidate_analogues wikiPageExternalLink US20060183773.
- List_of_methylphenidate_analogues wikiPageExternalLink PMC3469269.
- List_of_methylphenidate_analogues wikiPageExternalLink 15908207.
- List_of_methylphenidate_analogues wikiPageExternalLink 17228864.
- List_of_methylphenidate_analogues wikiPageExternalLink 21129986.
- List_of_methylphenidate_analogues wikiPageExternalLink 8786705.
- List_of_methylphenidate_analogues wikiPageExternalLink 0024320596000525.
- List_of_methylphenidate_analogues wikiPageExternalLink S0223523401012302.
- List_of_methylphenidate_analogues wikiPageExternalLink S0960894X04000630.
- List_of_methylphenidate_analogues wikiPageExternalLink quantitative-structure-activity-relationship-studies-of-threo-ZPaqENbXxH.
- List_of_methylphenidate_analogues wikiPageExternalLink 81.
- List_of_methylphenidate_analogues wikiPageExternalLink 82.
- List_of_methylphenidate_analogues wikiPageExternalLink 86.
- List_of_methylphenidate_analogues wikiPageExternalLink 87.
- List_of_methylphenidate_analogues wikiPageID "45690249".
- List_of_methylphenidate_analogues wikiPageLength "24065".
- List_of_methylphenidate_analogues wikiPageOutDegree "104".
- List_of_methylphenidate_analogues wikiPageRevisionID "707811772".
- List_of_methylphenidate_analogues wikiPageWikiLink 2-Benzylpiperidine.
- List_of_methylphenidate_analogues wikiPageWikiLink 3,4-Dichloromethylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink 4-Fluoromethylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink 4-Methylmethylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink AL-1095.
- List_of_methylphenidate_analogues wikiPageWikiLink Archibald_Hill.
- List_of_methylphenidate_analogues wikiPageWikiLink Aromaticity.
- List_of_methylphenidate_analogues wikiPageWikiLink Aryl.
- List_of_methylphenidate_analogues wikiPageWikiLink Carboxymethyl.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Carboxylate_esters.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Designer_drugs.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Dopamine_reuptake_inhibitors.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Euphoriants.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Methyl_esters.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Methylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Nootropics.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Norepinephrine-dopamine_reuptake_inhibitors.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Piperidines.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Sigma_agonists.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Stimulants.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Sympathomimetic_amines.
- List_of_methylphenidate_analogues wikiPageWikiLink Category:Vasoconstrictors.
- List_of_methylphenidate_analogues wikiPageWikiLink Chirality_(chemistry).
- List_of_methylphenidate_analogues wikiPageWikiLink Cocaine.
- List_of_methylphenidate_analogues wikiPageWikiLink Congener_(chemistry).
- List_of_methylphenidate_analogues wikiPageWikiLink Conjugate_acid.
- List_of_methylphenidate_analogues wikiPageWikiLink Cycloalkane.
- List_of_methylphenidate_analogues wikiPageWikiLink Daytrana.
- List_of_methylphenidate_analogues wikiPageWikiLink Demethylation.
- List_of_methylphenidate_analogues wikiPageWikiLink Desipramine.
- List_of_methylphenidate_analogues wikiPageWikiLink Desoxypipradrol.
- List_of_methylphenidate_analogues wikiPageWikiLink Dexmethylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink Dexoxadrol.
- List_of_methylphenidate_analogues wikiPageWikiLink Dextrorotation_and_levorotation.
- List_of_methylphenidate_analogues wikiPageWikiLink Diastereomer.
- List_of_methylphenidate_analogues wikiPageWikiLink Difemetorex.
- List_of_methylphenidate_analogues wikiPageWikiLink Diphenylprolinol.
- List_of_methylphenidate_analogues wikiPageWikiLink Enantiomer.
- List_of_methylphenidate_analogues wikiPageWikiLink Enpiroline.
- List_of_methylphenidate_analogues wikiPageWikiLink Ethylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink Etoxadrol.
- List_of_methylphenidate_analogues wikiPageWikiLink Eudysmic_ratio.
- List_of_methylphenidate_analogues wikiPageWikiLink Fluoxetine.
- List_of_methylphenidate_analogues wikiPageWikiLink G-force.
- List_of_methylphenidate_analogues wikiPageWikiLink Grey_market.
- List_of_methylphenidate_analogues wikiPageWikiLink HDMP-28.
- List_of_methylphenidate_analogues wikiPageWikiLink Isopropylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink List_of_Latin_phrases_(V).
- List_of_methylphenidate_analogues wikiPageWikiLink List_of_cocaine_analogues.
- List_of_methylphenidate_analogues wikiPageWikiLink List_of_phenyltropanes.
- List_of_methylphenidate_analogues wikiPageWikiLink Mazindol.
- List_of_methylphenidate_analogues wikiPageWikiLink Mean.
- List_of_methylphenidate_analogues wikiPageWikiLink Mefloquine.
- List_of_methylphenidate_analogues wikiPageWikiLink Methylmorphenate.
- List_of_methylphenidate_analogues wikiPageWikiLink Methylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink Nomifensine.
- List_of_methylphenidate_analogues wikiPageWikiLink O-2172.
- List_of_methylphenidate_analogues wikiPageWikiLink PH.
- List_of_methylphenidate_analogues wikiPageWikiLink Pethidine.
- List_of_methylphenidate_analogues wikiPageWikiLink Pipradrol.
- List_of_methylphenidate_analogues wikiPageWikiLink Propylphenidate.
- List_of_methylphenidate_analogues wikiPageWikiLink RTI-31.
- List_of_methylphenidate_analogues wikiPageWikiLink Racemic_mixture.
- List_of_methylphenidate_analogues wikiPageWikiLink Rimiterol.
- List_of_methylphenidate_analogues wikiPageWikiLink Ritalinic_acid.
- List_of_methylphenidate_analogues wikiPageWikiLink SCH-5472.
- List_of_methylphenidate_analogues wikiPageWikiLink Salt_(chemistry).
- List_of_methylphenidate_analogues wikiPageWikiLink Standard_deviation.
- List_of_methylphenidate_analogues wikiPageWikiLink Stereochemistry.
- List_of_methylphenidate_analogues wikiPageWikiLink Structural_analog.
- List_of_methylphenidate_analogues wikiPageWikiLink Substituted_phenylmorpholine.
- List_of_methylphenidate_analogues wikiPageWikiLink Vabicaserin.
- List_of_methylphenidate_analogues wikiPageWikiLink WIN_35428.
- List_of_methylphenidate_analogues wikiPageWikiLink File:CocaineHCl.svg.
- List_of_methylphenidate_analogues wikiPageWikiLink File:Cyclo-Methiodrone.png.
- List_of_methylphenidate_analogues wikiPageWikiLink File:Dexmethylphenidate_structure.svg.
- List_of_methylphenidate_analogues wikiPageWikiLink File:Ethylphenidate_3d_spin.gif.
- List_of_methylphenidate_analogues wikiPageWikiLink File:FlexedRingD-Threo-Methylphenidate.svg.