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- Linamarin abstract "Linamarin is a cyanogenic glucoside found in the leaves and roots of plants such as cassava, lima beans, and flax. It is a glucoside of acetone cyanohydrin. Upon exposure to enzymes and gut flora in the human intestine, linamarin and its methylated relative lotaustralin can decompose to the toxic chemical hydrogen cyanide; hence food uses of plants that contain significant quantities of linamarin require extensive preparation and detoxification. Ingested and absorbed linamarin is rapidly excreted in the urine and the glucoside itself does not appear to be acutely toxic. Consumption of cassava products with low levels of linamarin is widespread in the low-land tropics. Ingestion of food prepared from insufficiently processed cassava roots with high linamarin levels has been associated with dietary toxicity, particularly with the upper motor neuron disease known as konzo to the African populations in which it was first described by Trolli and later through the research network initiated by Hans Rosling. However, the toxicity is believed to be induced by ingestion of acetone cyanohydrin, the breakdown product of linamarin. Dietary exposure to linamarin has also been reported as a risk factor in developing glucose intolerance and diabetes, although studies in experimental animals have been inconsistent in reproducing this effect and may indicate that the primary effect is in aggravating existing conditions rather than inducing diabetes on its own.The generation of cyanide from linamarin is usually enzymatic and occurs when linamarin is exposed to linamarase, an enzyme normally expressed in the cell walls of cassava plants. Because the resulting cyanide derivatives are volatile, processing methods that induce such exposure are common traditional means of cassava preparation; foodstuffs are usually made from cassava after extended blanching, boiling, or fermentation. Food products made from cassava plants include garri (toasted cassava tubers), porridge-like fufu, the dough agbelima, and cassava flour.Recent research efforts have developed a transgenic cassava plant that stably downregulates linamarin production via RNA interference.".
- Linamarin iupacName "(hydroxymethyl)oxan-2-yl]oxy-propanenitrile".
- Linamarin iupacName "2-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-".
- Linamarin thumbnail Linamarin.svg?width=300.
- Linamarin wikiPageID "9435679".
- Linamarin wikiPageLength "5611".
- Linamarin wikiPageOutDegree "36".
- Linamarin wikiPageRevisionID "688605648".
- Linamarin wikiPageWikiLink Acetone_cyanohydrin.
- Linamarin wikiPageWikiLink Agbelima.
- Linamarin wikiPageWikiLink Animal_testing.
- Linamarin wikiPageWikiLink Blanching_(cooking).
- Linamarin wikiPageWikiLink Boiling.
- Linamarin wikiPageWikiLink Cassava.
- Linamarin wikiPageWikiLink Category:Cyanogenic_glycosides.
- Linamarin wikiPageWikiLink Category:Nitriles.
- Linamarin wikiPageWikiLink Category:Plant_toxins.
- Linamarin wikiPageWikiLink Cell_wall.
- Linamarin wikiPageWikiLink Cyanide.
- Linamarin wikiPageWikiLink Diabetes_mellitus.
- Linamarin wikiPageWikiLink Enzyme.
- Linamarin wikiPageWikiLink Fermentation_in_food_processing.
- Linamarin wikiPageWikiLink Flax.
- Linamarin wikiPageWikiLink Flour.
- Linamarin wikiPageWikiLink Fufu.
- Linamarin wikiPageWikiLink Garri.
- Linamarin wikiPageWikiLink Gastrointestinal_tract.
- Linamarin wikiPageWikiLink Glucoside.
- Linamarin wikiPageWikiLink Gut_flora.
- Linamarin wikiPageWikiLink Hans_Rosling.
- Linamarin wikiPageWikiLink Hydrogen_cyanide.
- Linamarin wikiPageWikiLink Impaired_glucose_tolerance.
- Linamarin wikiPageWikiLink Konzo.
- Linamarin wikiPageWikiLink Linamarase.
- Linamarin wikiPageWikiLink List_of_ethnic_groups_of_Africa.
- Linamarin wikiPageWikiLink Lotaustralin.
- Linamarin wikiPageWikiLink Methyl_group.
- Linamarin wikiPageWikiLink Phaseolus_lunatus.
- Linamarin wikiPageWikiLink RNA_interference.
- Linamarin wikiPageWikiLink Tuber.
- Linamarin wikiPageWikiLink Upper_motor_neuron.
- Linamarin wikiPageWikiLinkText "Linamarin".
- Linamarin wikiPageWikiLinkText "cyanide precursors".
- Linamarin wikiPageWikiLinkText "linamarin".
- Linamarin imagefile "Linamarin 3D sticks.png".
- Linamarin imagefile "Linamarin.svg".
- Linamarin imagefile "Linamarin3d.png".
- Linamarin iupacname "2".
- Linamarin iupacname "oxan-2-yl]oxy-propanenitrile".
- Linamarin othernames "Phaseolunatin".
- Linamarin verifiedfields "changed".
- Linamarin verifiedrevid "442096935".
- Linamarin watchedfields "changed".
- Linamarin wikiPageUsesTemplate Template:Cascite.
- Linamarin wikiPageUsesTemplate Template:Chembox.
- Linamarin wikiPageUsesTemplate Template:Chembox_Hazards.
- Linamarin wikiPageUsesTemplate Template:Chembox_Identifiers.
- Linamarin wikiPageUsesTemplate Template:Chembox_Properties.
- Linamarin wikiPageUsesTemplate Template:Chemspidercite.
- Linamarin wikiPageUsesTemplate Template:Ebicite.
- Linamarin wikiPageUsesTemplate Template:Glycosides.
- Linamarin wikiPageUsesTemplate Template:Keggcite.
- Linamarin wikiPageUsesTemplate Template:Stdinchicite.
- Linamarin subject Category:Cyanogenic_glycosides.
- Linamarin subject Category:Nitriles.
- Linamarin subject Category:Plant_toxins.
- Linamarin hypernym Glucoside.
- Linamarin type ChemicalCompound.
- Linamarin type ChemicalSubstance.
- Linamarin type Group.
- Linamarin type Chemical.
- Linamarin type Glycoside.
- Linamarin type Group.
- Linamarin type Nitrile.
- Linamarin type Toxin.
- Linamarin type ChemicalObject.
- Linamarin type Thing.
- Linamarin type Q11173.
- Linamarin comment "Linamarin is a cyanogenic glucoside found in the leaves and roots of plants such as cassava, lima beans, and flax. It is a glucoside of acetone cyanohydrin. Upon exposure to enzymes and gut flora in the human intestine, linamarin and its methylated relative lotaustralin can decompose to the toxic chemical hydrogen cyanide; hence food uses of plants that contain significant quantities of linamarin require extensive preparation and detoxification.".
- Linamarin label "Linamarin".
- Linamarin sameAs Q425157.
- Linamarin sameAs Linamarina.
- Linamarin sameAs Linamarin.
- Linamarin sameAs Linamarina.
- Linamarin sameAs لینامارین.
- Linamarin sameAs Linamarina.
- Linamarin sameAs リナマリン.
- Linamarin sameAs Linamarine.
- Linamarin sameAs m.0288vmh.
- Linamarin sameAs Линамарин.
- Linamarin sameAs Linamarin.
- Linamarin sameAs Linamarin.
- Linamarin sameAs Linamarin.
- Linamarin sameAs Q425157.
- Linamarin wasDerivedFrom Linamarin?oldid=688605648.
- Linamarin depiction Linamarin.svg.
- Linamarin isPrimaryTopicOf Linamarin.